[POCKETOME]
 

Search Results

3313 entries [expand]
Show only: ⁠Human; ⁠Other mammals; ⁠Gram-positive bacteria; ⁠Gram-negative bacteria; ⁠Archaea; ⁠Virus; ⁠Other.
[<<] entries 101–200 [>>]

ACTP2_STIHL_1_175 DELTA-stichotoxin-She4b [Actinoporin family. Sea anemone subfamily]

volume: 108. Å3; shape: 0.54; buriedness: 0.88

negative: 0.; positive: 0.15; polar: 0.54; backbone: 0.31; hydrophobic: 0.

Domains/regions: [R] N-terminal region

PDB: 1gwy, 1o71, 1o72

HET: pc

ACTPC_ACTFR_1_179 DELTA-actitoxin-Afr1a [Actinoporin family. Sea anemone subfamily]

volume: 1532. Å3; shape: 0.96; buriedness: 0.5

negative: 0.03; positive: 0.07; polar: 0.36; backbone: 0.36; hydrophobic: 0.18

Domains/regions: [R] Trp-rich region

PDB: 3lim, 3vwi, 3w9p, 3zwg, 3zwj, 4tsl, 4tsn, 4tso, 4tsp, 4tsq, 4tsy, 4wdc, 5bpg, 5gwf

HET: hxg, hxj, lda, pc

ACVR1_HUMAN_199_499 Activin receptor type-1 [Protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily]

volume: 348. Å3; shape: 0.5; buriedness: 0.79

negative: 0.05; positive: 0.09; polar: 0.15; backbone: 0.38; hydrophobic: 0.33

Domains/regions: [D] Protein kinase

PDB: 3h9r, 3mtf, 3oom, 3q4u, 4bgg, 4c02, 4dym, 5oxg, 5oy6, 6eix

HET: 507, 844, a3f, b4b, b4e, iyz, ldn, tak

ADA17_HUMAN_215_479 Disintegrin and metalloproteinase domain-containing protein 17

volume: 662. Å3; shape: 0.55; buriedness: 0.75

negative: 0.07; positive: 0.11; polar: 0.07; backbone: 0.55; hydrophobic: 0.2

Domains/regions: [D] Peptidase M12B

PDB: 1bkc, 1zxc, 2a8h, 2ddf, 2fv5, 2fv9, 2i47, 2oi0, 3b92, 3cki, 3e8r, 3edz, 3ewj, 3g42, 3kmc, 3kme, 3l0t, 3l0v, 3le9, 3lea, 3lgp, 3o64

HET: 002, 283, 403, 440, 4nh, 50x, 541, 550, 615, 642, 724, 727, 786, 792, ih6, inn, kgy, z59, z93, z94

ADA2_HUMAN_28_511 Adenosine deaminase 2 [Metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily]

volume: 174. Å3; shape: 0.54; buriedness: 0.98

negative: 0.32; positive: 0.32; polar: 0.; backbone: 0.07; hydrophobic: 0.29

Domains/regions: [R] Substrate binding

PDB: 3lgd, 3lgg

HET: cfe

ADA33_HUMAN_204_410 Disintegrin and metalloproteinase domain-containing protein 33

volume: 209. Å3; shape: 0.66; buriedness: 0.73

negative: 0.08; positive: 0.19; polar: 0.15; backbone: 0.46; hydrophobic: 0.12

Domains/regions: [D] Peptidase M12B

PDB: 1r54, 1r55

HET: 097

ADA_HUMAN_2_358 Adenosine deaminase [Metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family]

volume: 385. Å3; shape: 0.7; buriedness: 0.9

negative: 0.2; positive: 0.1; polar: 0.05; backbone: 0.27; hydrophobic: 0.38

PDB: 1krm, 1ndv, 1ndw, 1ndy, 1ndz, 1o5r, 1qxl, 1uml, 1v79, 1v7a, 1vfl, 1w1i, 1wxy, 1wxz, 2bgn, 2e1w, 2z7g, 3iar

HET: 3d1, eh9, fr0, fr2, fr3, fr4, fr5, fr6, fr7, fr8, fr9, frc, frk, frl, prh

ADA_MOUSE_4_352 Adenosine deaminase [Metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family]

volume: 163. Å3; shape: 0.52; buriedness: 0.97

negative: 0.26; positive: 0.14; polar: 0.01; backbone: 0.17; hydrophobic: 0.42

PDB: 1a4l, 1a4m, 1add, 1fkw, 1fkx, 1uio, 1uip, 2ada, 3km8, 3mvi, 3mvt, 3t1g

HET: 1da, 9di, dcf, hpr, prh, pur

ADAS_CAVPO_15_658 Alkyldihydroxyacetonephosphate synthase, peroxisomal [FAD-binding oxidoreductase/transferase type 4 family]

volume: 1306. Å3; shape: 0.37; buriedness: 0.94

negative: 0.02; positive: 0.05; polar: 0.19; backbone: 0.48; hydrophobic: 0.25

Domains/regions: [D] FAD-binding PCMH-type, [R] Important for enzyme activity

PDB: 4bby, 4bc7, 4bc9, 4bca, 5adz, 5ae1, 5ae2, 5ae3

HET: 1do, awb, b2z, cnv, fad, fyc, kqs

ADCY2_RAT_870_1082 Adenylate cyclase type 2 [Adenylyl cyclase class-4/guanylyl cyclase family]

volume: 698. Å3; shape: 0.92; buriedness: 0.37

negative: 0.1; positive: 0.16; polar: 0.19; backbone: 0.32; hydrophobic: 0.23

PDB: 1ab8, 1azs, 1cjk, 1cjt, 1cju, 1cjv, 1cs4, 1cul, 1tl7, 1u0h, 2gvd, 2gvz, 3c14, 3c15, 3c16, 3g82, 3maa

HET: 101, 103, 128, 3po, atp, dad, fok, mi3, ona, onm, tat

ADCYA_HUMAN_1_469 Adenylate cyclase type 10 [Adenylyl cyclase class-4/guanylyl cyclase family]

volume: 256. Å3; shape: 0.5; buriedness: 0.8

negative: 0.07; positive: 0.07; polar: 0.25; backbone: 0.39; hydrophobic: 0.23

Domains/regions: [D] Guanylate cyclase 2

PDB: 4clf, 4clk, 4cll, 4clp, 4cls, 4clt, 4clu, 4clw, 4cly, 4clz, 4cm0, 4cm2, 4oya, 4oyb, 4oyi, 4oym, 4oyo, 4oyp, 4oyw, 4oyx, 4oyz, 4oz2, 4oz3, 4ust, 4usu, 4usv, 4usw, 5d0r, 5iv3, 5iv4

HET: 4ds

ADE_PSEAE_1_316 Adenine deaminase [Metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily]

volume: 77. Å3; shape: 0.87; buriedness: 1.

negative: 0.34; positive: 0.26; polar: 0.09; backbone: 0.09; hydrophobic: 0.23

PDB: 3ou8, 3pan, 3pao, 3pbm

HET: ade, es4, hpa

ADH1A_HUMAN_2_375 Alcohol dehydrogenase 1A [Zinc-containing alcohol dehydrogenase family]

volume: 124. Å3; shape: 0.72; buriedness: 0.92

negative: 0.; positive: 0.09; polar: 0.09; backbone: 0.04; hydrophobic: 0.78

PDB: 1hso, 1u3t

HET: ccb, pyz

ADH1E_HORSE_2_375 Alcohol dehydrogenase E chain [Zinc-containing alcohol dehydrogenase family. Class-I subfamily]

volume: 796. Å3; shape: 0.41; buriedness: 0.91

negative: 0.02; positive: 0.13; polar: 0.06; backbone: 0.43; hydrophobic: 0.35

PDB: 1a71, 1a72, 1adb, 1adc, 1adf, 1adg, 1axe, 1axg, 1bto, 1het, 1heu, 1hf3, 1hld, 1ju9, 1lde, 1ldy, 1mg0, 1mgo, 1n8k, 1n92, 1p1r, 1qlh, 1qlj, 1qv6, 1qv7, 1ye3, 2jhf, 2jhg, 2ohx, 2oxi, 3bto, 3oq6, 4dwv, 4dxh, 4nfh, 4nfs, 4ng5, 4xd2, 5adh, 5cdg, 5cds, 5cdt, 5cdu, 5kcp, 5kcz, 5kj1, 5kj6, 5kjc, 5kje, 5kjf, 5vj5, 5vjg, 5vkr, 5vl0, 5vn1, 6adh, 7adh, 8adh

HET: 0bp, 24b, apr, bnf, brb, cnd, cxf, dfb, etf, fpi, ibo, mrd, nad, nai, naj, nmh, ntn, nwh, pad, pfb, phn, pyz, pzo, sad, ssb, tad

ADH1G_HUMAN_2_375 Alcohol dehydrogenase 1C [Zinc-containing alcohol dehydrogenase family]

volume: 139. Å3; shape: 0.43; buriedness: 0.95

negative: 0.; positive: 0.08; polar: 0.12; backbone: 0.08; hydrophobic: 0.72

PDB: 1ht0, 1u3w

HET: fxy

ADHX_HUMAN_2_374 Alcohol dehydrogenase class-3 [Zinc-containing alcohol dehydrogenase family. Class-III subfamily]

volume: 340. Å3; shape: 0.65; buriedness: 0.79

negative: 0.; positive: 0.21; polar: 0.28; backbone: 0.; hydrophobic: 0.51

PDB: 1m6h, 1m6w, 1ma0, 1mc5, 1mp0, 1teh, 2fze, 2fzw, 3qj5

HET: 022, 12h, ahe, dao, zn

ADK_HUMAN_15_362 Adenosine kinase [Carbohydrate kinase PfkB family]

volume: 290. Å3; shape: 0.49; buriedness: 0.96

negative: 0.08; positive: 0.; polar: 0.2; backbone: 0.41; hydrophobic: 0.31

PDB: 1bx4, 2i6a, 2i6b, 4o1l

HET: 5i5, 89i, adn, ho4

ADRB1_MELGA_31_367_TM Beta-1 adrenergic receptor [G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily]

volume: 295. Å3; shape: 0.56; buriedness: 0.92

negative: 0.06; positive: 0.; polar: 0.35; backbone: 0.16; hydrophobic: 0.42

Domains/regions: [R] Agonist and antagonist binding

PDB: 2vt4, 2y00, 2y01, 2y02, 2y03, 2y04, 2ycw, 2ycx, 2ycy, 2ycz, 3zpq, 3zpr, 4ami, 4amj, 4bvn, 4gpo, 5a8e, 5f8u

HET: 3wc, 5fw, 68h, cau, cvd, g90, i32, p32, whj, xf5, xtk, y00

ADRB2_HUMAN_26_357_EH234 Beta-2 adrenergic receptor [G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily]

volume: 530. Å3; shape: 0.6; buriedness: 0.54

negative: 0.; positive: 0.; polar: 0.24; backbone: 0.; hydrophobic: 0.76

PDB: 2r4r, 2r4s, 2rh1, 3d4s, 3kj6, 3ny8, 3ny9, 3nya, 3p0g, 3pds, 3sn6, 4gbr, 4lde, 4ldl, 4ldo, 4qkx, 5d5a, 5d5b, 5d6l, 5jqh, 5x7d

HET: clr

ADRB2_HUMAN_26_357_Galpha Beta-2 adrenergic receptor [G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily]

volume: 2096. Å3; shape: 0.65; buriedness: 0.64

negative: 0.05; positive: 0.13; polar: 0.14; backbone: 0.49; hydrophobic: 0.2

PDB: 2r4r, 2r4s, 2rh1, 3d4s, 3kj6, 3ny8, 3ny9, 3nya, 3p0g, 3pds, 3sn6, 4gbr, 4lde, 4ldl, 4ldo, 4qkx, 5d5a, 5d5b, 5d6l, 5jqh, 5x7d

HET: 8vs, bu1

ADRB2_HUMAN_26_357_TM Beta-2 adrenergic receptor [G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily]

volume: 307. Å3; shape: 0.53; buriedness: 0.93

negative: 0.07; positive: 0.04; polar: 0.37; backbone: 0.1; hydrophobic: 0.42

Domains/regions: [R] Agonist and antagonist binding

PDB: 2r4r, 2r4s, 2rh1, 3d4s, 3kj6, 3ny8, 3ny9, 3nya, 3p0g, 3pds, 3sn6, 4gbr, 4lde, 4ldl, 4ldo, 4qkx, 5d5a, 5d5b, 5d6l, 5jqh, 5x7d

HET: 35v, ale, cau, erc, jrz, jsz, jtz, p0g, tim, xqc

ADT1_BOVIN_2_298_cxt ADP/ATP translocase 1 [Mitochondrial carrier (TC 2.A.29) family]

volume: 466. Å3; shape: 0.59; buriedness: 0.72

negative: 0.06; positive: 0.24; polar: 0.21; backbone: 0.33; hydrophobic: 0.15

Domains/regions: [R] Important for transport activity

PDB: 1okc, 2c3e

HET: cxt

AEQ2_AEQVI_8_196 Aequorin-2 [Aequorin family]

volume: 359. Å3; shape: 0.7; buriedness: 1.

negative: 0.; positive: 0.14; polar: 0.14; backbone: 0.18; hydrophobic: 0.55

Domains/regions: [D] EF-hand 1, [D] EF-hand 2, [D] EF-hand 3, [D] EF-hand 4, [R] May interact with the chromophore

PDB: 1ej3, 1uhh, 1uhi, 1uhj, 1uhk

HET: czb, czh, czi, czn, czp

AER_ARATH_1_345 NADPH-dependent oxidoreductase 2-alkenal reductase [NADP-dependent oxidoreductase L4BD family]

volume: 137. Å3; shape: 0.53; buriedness: 0.81

negative: 0.; positive: 0.; polar: 0.64; backbone: 0.; hydrophobic: 0.36

PDB: 2j3h, 2j3i, 2j3j, 2j3k

HET: hc4, hne

AFLC_ASPPU_1305_1660 Norsolorinic acid synthase

volume: 604. Å3; shape: 0.3; buriedness: 0.86

negative: 0.; positive: 0.06; polar: 0.11; backbone: 0.41; hydrophobic: 0.43

Domains/regions: [R] Product template (PT) domain

PDB: 3hrq, 3hrr, 5kbz

HET: 3b2, hc8, plm

AGAA_GEOSE_1_729 Alpha-galactosidase AgaA [Glycosyl hydrolase 36 family]

volume: 298. Å3; shape: 0.48; buriedness: 0.97

negative: 0.3; positive: 0.19; polar: 0.08; backbone: 0.13; hydrophobic: 0.3

Domains/regions: [R] Substrate binding

PDB: 4fnp, 4fnq, 4fnr, 4fns, 4fnt

HET: dgj, raf

AGAL_HUMAN_32_429 Alpha-galactosidase A [Glycosyl hydrolase 27 family]

volume: 186. Å3; shape: 0.78; buriedness: 0.93

negative: 0.44; positive: 0.19; polar: 0.18; backbone: 0.; hydrophobic: 0.19

Domains/regions: [R] Substrate binding

PDB: 1r46, 1r47, 3gxn, 3gxp, 3gxt, 3hg2, 3hg3, 3hg4, 3hg5, 3lx9, 3lxa, 3lxb, 3lxc, 3s5y, 3s5z, 3tv8, 4nxs

HET: 2oz, 7jz, dgj, gla, glc, noj

AGAL_THEMA_1_552 Alpha-galactosidase [Glycosyl hydrolase 36 family]

volume: 151. Å3; shape: 0.76; buriedness: 0.91

negative: 0.33; positive: 0.17; polar: 0.08; backbone: 0.; hydrophobic: 0.42

Domains/regions: [R] Substrate binding

PDB: 1zy9, 5m0x, 5m12, 5m16, 5m1i

HET: 7d0, 7d2, 7d8

AGI1_WHEAT_27_201_glycopep Agglutinin isolectin 1

volume: 992. Å3; shape: 0.53; buriedness: 0.56

negative: 0.19; positive: 0.04; polar: 0.39; backbone: 0.13; hydrophobic: 0.26

Domains/regions: [D] Chitin-binding type-1 1, [D] Chitin-binding type-1 2, [D] Chitin-binding type-1 3, [R] Substrate binding

PDB: 1wgc, 2cwg, 2uvo, 2x3t, 4aml, 7wga

HET: dbb, gal, gyu, gyv, ndg, sia

AGM1_CANAX_1_544 Phosphoacetylglucosamine mutase [Phosphohexose mutase family]

volume: 208. Å3; shape: 0.57; buriedness: 0.81

negative: 0.11; positive: 0.18; polar: 0.3; backbone: 0.32; hydrophobic: 0.11

Domains/regions: [R] Substrate binding

PDB: 2dka, 2dkc, 2dkd

HET: 16g, ng1

AGO2_HUMAN_438_575 Protein argonaute-2 [Argonaute family. Ago subfamily]

volume: 1531. Å3; shape: 0.54; buriedness: 0.66

negative: 0.; positive: 0.16; polar: 0.28; backbone: 0.47; hydrophobic: 0.08

Domains/regions: [D] Piwi, [R] Interaction with guide RNA

PDB: 3luc, 3lud, 3lug, 3luh, 3luj, 3luk, 3qx8, 3qx9, 4f3t, 4ola, 4olb, 4w5n, 4w5o, 4w5q, 4w5r, 4w5t, 4z4c, 4z4d, 4z4e, 4z4f, 4z4g, 4z4h, 4z4i, 5js1, 5js2, 5ki6, 5t7b, 5wea

HET: 5gp, 6nw, 6oo, 6op, 6u0, amp, atp, c5p, f2t, gtg, u5p, uft, uvp

AGOG_PYRAE_1_256 N-glycosylase/DNA lyase [Archaeal N-glycosylase/DNA lyase (AGOG) family]

volume: 166. Å3; shape: 0.76; buriedness: 0.94

negative: 0.17; positive: 0.13; polar: 0.09; backbone: 0.3; hydrophobic: 0.3

Domains/regions: [R] Helix-hairpin-helix

PDB: 1xqo, 1xqp

HET: 8hg

AGTR1_HUMAN_14_317 Type-1 angiotensin II receptor [G-protein coupled receptor 1 family]

volume: 338. Å3; shape: 0.55; buriedness: 0.81

negative: 0.; positive: 0.08; polar: 0.31; backbone: 0.15; hydrophobic: 0.46

PDB: 4yay, 4zud

HET: olm, zd7

AGTR2_HUMAN_35_335 Type-2 angiotensin II receptor [G-protein coupled receptor 1 family]

volume: 492. Å3; shape: 0.63; buriedness: 0.95

negative: 0.; positive: 0.08; polar: 0.28; backbone: 0.14; hydrophobic: 0.49

PDB: 5unf, 5ung, 5unh

HET: 8em, 8es

AHK4_ARATH_149_418 Histidine kinase 4

volume: 167. Å3; shape: 0.49; buriedness: 0.99

negative: 0.07; positive: 0.; polar: 0.07; backbone: 0.34; hydrophobic: 0.53

Domains/regions: [D] CHASE

PDB: 3t4j, 3t4k, 3t4l, 3t4o, 3t4q, 3t4s, 3t4t

HET: emu, h35, wa1, wa2, zea, zip

AHLLA_BACTK_1_250 N-acyl homoserine lactonase AiiA [Metallo-beta-lactamase superfamily]

volume: 333. Å3; shape: 0.53; buriedness: 0.87

negative: 0.15; positive: 0.21; polar: 0.11; backbone: 0.2; hydrophobic: 0.33

PDB: 2a7m, 2br6, 2btn, 3dha, 3dhb, 3dhc, 4j5f, 4j5h, 5eh9, 5eht

HET: 1k4, c6l, cyk, hed, hsl

AIPL1_HUMAN_1_161 Aryl-hydrocarbon-interacting protein-like 1

volume: 296. Å3; shape: 0.54; buriedness: 0.81

negative: 0.; positive: 0.05; polar: 0.; backbone: 0.15; hydrophobic: 0.79

Domains/regions: [D] PPIase FKBP-type

PDB: 5u9a, 5u9i, 5u9j, 5u9k, 5v35

HET: far, ger

AK1A1_HUMAN_1_325 Alcohol dehydrogenase [NADP(+)] [Aldo/keto reductase family]

volume: 220. Å3; shape: 0.92; buriedness: 0.79

negative: 0.; positive: 0.1; polar: 0.08; backbone: 0.21; hydrophobic: 0.62

PDB: 1ae4, 1cwn, 1hqt, 2alr, 3cv7, 3fx4, 3h4g, 4gac

HET: c2u, fid, fx4

AK1BA_HUMAN_1_316 Aldo-keto reductase family 1 member B10 [Aldo/keto reductase family]

volume: 409. Å3; shape: 0.69; buriedness: 0.81

negative: 0.; positive: 0.15; polar: 0.09; backbone: 0.08; hydrophobic: 0.67

PDB: 1zua, 4ga8, 4gab, 4gq0, 4gqg, 4i5x, 4icc, 4jih, 4jii, 4wev, 4xzl, 4xzm, 4xzn, 5lik, 5liu, 5liw, 5lix, 5liy, 5m2f

HET: 1wx, 388, 64i, dqp, epr, f49, fid, flf, mk4, qap, sbi, suz, tol, uv8, w8x, zst

AK1C1_HUMAN_1_323 Aldo-keto reductase family 1 member C1 [Aldo/keto reductase family]

volume: 338. Å3; shape: 0.58; buriedness: 0.83

negative: 0.05; positive: 0.16; polar: 0.16; backbone: 0.; hydrophobic: 0.62

PDB: 1mrq, 3c3u, 3gug, 3nty, 4yvp

HET: 5p3, c2u, gbm, str

AK1C2_HUMAN_1_323 Aldo-keto reductase family 1 member C2 [Aldo/keto reductase family]

volume: 277. Å3; shape: 0.51; buriedness: 0.76

negative: 0.; positive: 0.1; polar: 0.2; backbone: 0.1; hydrophobic: 0.59

PDB: 1ihi, 1j96, 1xjb, 2hdj, 2ipj, 4jq1, 4jq2, 4jq3, 4jq4, 4jqa, 4jtq, 4jtr, 4l1w, 4l1x, 4xo6, 4xo7

HET: 5sd, aox, asd, ffa, flp, ibp, id8, imn, iu5, izp, nps, str, suz, tes, zom

AK1C3_HUMAN_1_323 Aldo-keto reductase family 1 member C3 [Aldo/keto reductase family]

volume: 482. Å3; shape: 0.82; buriedness: 0.86

negative: 0.; positive: 0.07; polar: 0.44; backbone: 0.; hydrophobic: 0.48

PDB: 1ry0, 1ry8, 1s1p, 1s1r, 1s2a, 1s2c, 1xf0, 1zq5, 2f38, 2fgb, 3r43, 3r58, 3r6i, 3r7m, 3r8g, 3r8h, 3r94, 3ufy, 3ug8, 3ugr, 3uwe, 4dbs, 4dbu, 4dbw, 4dz5, 4fa3, 4fal, 4fam, 4h7c, 4hmn, 4wdt, 4wdu, 4wdw, 4wdx, 4wrh, 4xvd, 4xve, 4yvv, 4yvx, 4zfc, 5hnt, 5hnu, 5jm5

HET: 0hv, 0sl, 0sz, 0t0, 10h, 15m, 16j, 511, 65d, 6lg, asd, bt9, e04, flf, flr, gbm, gcz, gmr, id8, imn, izp, jms, nps, npx, p6g, pg2, pg4, qap, rut, suz, vjj, wds, wdt, wdu, wdv, wdw, wdx, yy1, yy2, zom

AK1CL_MOUSE_2_323 Aldo-keto reductase family 1 member C21 [Aldo/keto reductase family]

volume: 228. Å3; shape: 0.6; buriedness: 0.86

negative: 0.; positive: 0.17; polar: 0.42; backbone: 0.17; hydrophobic: 0.24

PDB: 2he5, 2he8, 2hej, 2ipf, 2ipg, 2p5n, 3cv6, 3fjn

HET: ffa, hxs

AK1D1_HUMAN_2_326 3-oxo-5-beta-steroid 4-dehydrogenase [Aldo/keto reductase family]

volume: 295. Å3; shape: 0.68; buriedness: 0.79

negative: 0.09; positive: 0.04; polar: 0.38; backbone: 0.; hydrophobic: 0.5

PDB: 3bur, 3buv, 3bv7, 3caq, 3cas, 3cav, 3cmf, 3cot, 3dop, 3g1r, 3uzw, 3uzx, 3uzy, 3uzz

HET: aom, aox, asd, bdt, ci2, fit, pdn, str, tes

AKT1_HUMAN_1_137 RAC-alpha serine/threonine-protein kinase [Protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily]

volume: 554. Å3; shape: 0.74; buriedness: 0.83

negative: 0.; positive: 0.11; polar: 0.25; backbone: 0.31; hydrophobic: 0.33

Domains/regions: [D] PH

PDB: 1h10, 1unp, 1unq, 1unr, 2uvm, 2uzr, 2uzs, 3o96, 4ejn, 5kcv

HET: 0r4, 6s1, iqo

AKT1_HUMAN_137_445_pep RAC-alpha serine/threonine-protein kinase [Protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily]

volume: 732. Å3; shape: 0.72; buriedness: 0.59

negative: 0.09; positive: 0.03; polar: 0.14; backbone: 0.43; hydrophobic: 0.3

Domains/regions: [D] AGC-kinase C-terminal, [D] Protein kinase, [R] Inhibitor binding

PDB: 3cqu, 3cqw, 3mv5, 3mvh, 3o96, 3ocb, 3ow4, 3qkk, 3qkl, 3qkm, 4ejn, 4ekk, 4ekl, 4gv1, 5kcv

HET: 0rf, 0xz, anp, cqu, cqw, mn, sm9, smh, smr, smy, wfe, xfe, xm1

AKT2_HUMAN_145_478_pep RAC-beta serine/threonine-protein kinase [Protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily]

volume: 896. Å3; shape: 0.8; buriedness: 0.62

negative: 0.11; positive: 0.04; polar: 0.12; backbone: 0.43; hydrophobic: 0.3

Domains/regions: [D] Protein kinase, [R] Inhibitor binding

PDB: 1gzk, 1gzn, 1gzo, 1mrv, 1mry, 1o6k, 1o6l, 2jdo, 2jdr, 2uw9, 2x39, 2xh5, 3d0e, 3e87, 3e88, 3e8d

HET: anp, g93, g95, g96, g98, gvp, i5s, l20, mn, x37, x39

AL1A1_HUMAN_4_501 Retinal dehydrogenase 1 [Aldehyde dehydrogenase family]

volume: 380. Å3; shape: 0.71; buriedness: 0.82

negative: 0.; positive: 0.03; polar: 0.14; backbone: 0.29; hydrophobic: 0.54

PDB: 1bxs, 4wb9, 4wj9, 4wp7, 4wpn, 4x4l, 5abm, 5ac0, 5ac1, 5ac2, 5l2m, 5l2n, 5l2o, 5tei

HET: 3sr, 3st, 3xg, 6zu, 6zy, k9p, m39

AL1A2_HUMAN_24_518 Retinal dehydrogenase 2 [Aldehyde dehydrogenase family]

volume: 425. Å3; shape: 0.74; buriedness: 0.84

negative: 0.; positive: 0.; polar: 0.16; backbone: 0.38; hydrophobic: 0.46

PDB: 1bi9, 4x2q, 6alj, 6b5g, 6b5h, 6b5i

HET: cqy, cu4, cw2

AL1L1_HUMAN_1_307 Cytosolic 10-formyltetrahydrofolate dehydrogenase

volume: 110. Å3; shape: 0.66; buriedness: 0.96

negative: 0.06; positive: 0.; polar: 0.; backbone: 0.55; hydrophobic: 0.39

Domains/regions: [R] GART, [R] Substrate binding

PDB: 1s3i, 2bw0, 2cfi

HET: zzz

AL3A1_HUMAN_2_453 Aldehyde dehydrogenase, dimeric NADP-preferring [Aldehyde dehydrogenase family]

volume: 266. Å3; shape: 0.49; buriedness: 0.96

negative: 0.04; positive: 0.06; polar: 0.39; backbone: 0.13; hydrophobic: 0.38

PDB: 3sza, 3szb, 4h80, 4l1o, 4l2o

HET: 04t, 1dd, 1vl, i1e

AL7A1_HUMAN_27_537 Alpha-aminoadipic semialdehyde dehydrogenase [Aldehyde dehydrogenase family]

volume: 185. Å3; shape: 0.85; buriedness: 0.92

negative: 0.07; positive: 0.; polar: 0.19; backbone: 0.25; hydrophobic: 0.5

PDB: 2j6l, 4x0t, 4x0u, 4zuk, 4zul, 4zvw, 4zvx, 4zvy

HET: 3w9, un1

ALBU_BOVIN_25_607 Serum albumin [ALB/AFP/VDB family]

volume: 196. Å3; shape: 0.57; buriedness: 0.97

negative: 0.; positive: 0.22; polar: 0.19; backbone: 0.15; hydrophobic: 0.43

Domains/regions: [D] Albumin 1, [D] Albumin 2

PDB: 3v03, 4f5s, 4jk4, 4luf, 4luh, 4or0, 5orf, 5ori, 5osw, 5otb

HET: 2q5, diu

ALBU_HORSE_25_607 Serum albumin [ALB/AFP/VDB family]

volume: 476. Å3; shape: 0.46; buriedness: 0.81

negative: 0.04; positive: 0.11; polar: 0.12; backbone: 0.33; hydrophobic: 0.4

Domains/regions: [D] Albumin 2, [D] Albumin 3

PDB: 3v08, 4f5t, 4f5u, 4j2v, 4ot2, 4zbq, 4zbr, 5dby, 5dqf, 5hoz, 5id9, 5iih, 5iiu, 5iix, 5ij5, 5ije, 5v0v, 6ci6

HET: 6a4, 8qp, 8qs, cze, kna, mli, nps

ALBU_HUMAN_25_609_diazepamSite Serum albumin [ALB/AFP/VDB family]

volume: 645. Å3; shape: 0.79; buriedness: 0.95

negative: 0.02; positive: 0.11; polar: 0.12; backbone: 0.28; hydrophobic: 0.46

Domains/regions: [D] Albumin 2, [D] Albumin 3

PDB: 1ao6, 1bj5, 1bke, 1bm0, 1e78, 1e7a, 1e7b, 1e7c, 1e7e, 1e7f, 1e7g, 1e7h, 1e7i, 1gni, 1gnj, 1h9z, 1ha2, 1hk1, 1hk2, 1hk3, 1hk4, 1hk5, 1n5u, 1o9x, 1tf0, 1uor, 2bx8, 2bxa, 2bxb, 2bxc, 2bxd, 2bxe, 2bxf, 2bxg, 2bxh, 2bxi, 2bxk, 2bxl, 2bxm, 2bxn, 2bxo, 2bxp, 2bxq, 2i2z, 2i30, 2vdb, 2vue, 2vuf, 2xsi, 2xvq, 2xvu, 2xvv, 2xvw, 2xw0, 2xw1, 2ydf, 3a73, 3b9l, 3b9m, 3cx9, 3jqz, 3jry, 3lu6, 3lu7, 3lu8, 3sqj, 3tdl, 3uiv, 4bke, 4e99, 4emx, 4g03, 4g04, 4hgk, 4hgm, 4iw1, 4iw2, 4k2c, 4k71, 4l8u, 4l9k, 4l9q, 4la0, 4lb2, 4lb9, 4n0f, 4s1y, 4z69, 5gix, 5giy, 5id7, 5ifo, 5ijf, 5ujb, 5vnw, 5x52, 5yoq, 6ezq

HET: 1fl, 6a4, 9dn, 9ds, 9nf, 9nv, acd, c1f, c7k, clt, dao, dka, dzp, f15, hlt, ibp, ios, myr, oca, ola, p8s, pfl, plm, ste, t44

ALBU_HUMAN_25_609_halothaneSite Serum albumin [ALB/AFP/VDB family]

volume: 1204. Å3; shape: 0.74; buriedness: 0.84

negative: 0.03; positive: 0.15; polar: 0.08; backbone: 0.39; hydrophobic: 0.36

Domains/regions: [D] Albumin 2, [D] Albumin 3

PDB: 1ao6, 1bj5, 1bke, 1bm0, 1e78, 1e7a, 1e7b, 1e7c, 1e7e, 1e7f, 1e7g, 1e7h, 1e7i, 1gni, 1gnj, 1h9z, 1ha2, 1hk1, 1hk2, 1hk3, 1hk4, 1hk5, 1n5u, 1o9x, 1tf0, 1uor, 2bx8, 2bxa, 2bxb, 2bxc, 2bxd, 2bxe, 2bxf, 2bxg, 2bxh, 2bxi, 2bxk, 2bxl, 2bxm, 2bxn, 2bxo, 2bxp, 2bxq, 2i2z, 2i30, 2vdb, 2vue, 2vuf, 2xsi, 2xvq, 2xvu, 2xvv, 2xvw, 2xw0, 2xw1, 2ydf, 3a73, 3b9l, 3b9m, 3cx9, 3jqz, 3jry, 3lu6, 3lu7, 3lu8, 3sqj, 3tdl, 3uiv, 4bke, 4e99, 4emx, 4g03, 4g04, 4hgk, 4hgm, 4iw1, 4iw2, 4k2c, 4k71, 4l8u, 4l9k, 4l9q, 4la0, 4lb2, 4lb9, 4n0f, 4s1y, 4z69, 5gix, 5giy, 5id7, 5ifo, 5ijf, 5ujb, 5vnw, 5x52, 5yoq, 6ezq

HET: 11d, 1fl, 6a4, 9nf, acd, c7k, dao, dif, dka, hlt, ibp, idb, imn, imx, ipx, myr, ola, p8s, plm, rwf, ste, swf

ALBU_HUMAN_25_609_naproxenSite Serum albumin [ALB/AFP/VDB family]

volume: 952. Å3; shape: 0.69; buriedness: 0.88

negative: 0.02; positive: 0.17; polar: 0.1; backbone: 0.38; hydrophobic: 0.32

Domains/regions: [D] Albumin 1, [D] Albumin 2

PDB: 1ao6, 1bj5, 1bke, 1bm0, 1e78, 1e7a, 1e7b, 1e7c, 1e7e, 1e7f, 1e7g, 1e7h, 1e7i, 1gni, 1gnj, 1h9z, 1ha2, 1hk1, 1hk2, 1hk3, 1hk4, 1hk5, 1n5u, 1o9x, 1tf0, 1uor, 2bx8, 2bxa, 2bxb, 2bxc, 2bxd, 2bxe, 2bxf, 2bxg, 2bxh, 2bxi, 2bxk, 2bxl, 2bxm, 2bxn, 2bxo, 2bxp, 2bxq, 2i2z, 2i30, 2vdb, 2vue, 2vuf, 2xsi, 2xvq, 2xvu, 2xvv, 2xvw, 2xw0, 2xw1, 2ydf, 3a73, 3b9l, 3b9m, 3cx9, 3jqz, 3jry, 3lu6, 3lu7, 3lu8, 3sqj, 3tdl, 3uiv, 4bke, 4e99, 4emx, 4g03, 4g04, 4hgk, 4hgm, 4iw1, 4iw2, 4k2c, 4k71, 4l8u, 4l9k, 4l9q, 4la0, 4lb2, 4lb9, 4n0f, 4s1y, 4z69, 5gix, 5giy, 5id7, 5ifo, 5ijf, 5ujb, 5vnw, 5x52, 5yoq, 6ezq

HET: 198, 6ak, 9az, 9dn, 9ne, 9nr, 9tp, acd, azq, azz, b3i, bla, dao, dif, dka, dm5, ehf, f15, fe, fua, hem, imn, iqx, myr, nps, ola, pj2, plm, sal, ste

ALBU_HUMAN_25_609_warfarinSite Serum albumin [ALB/AFP/VDB family]

volume: 1070. Å3; shape: 0.54; buriedness: 0.87

negative: 0.04; positive: 0.17; polar: 0.12; backbone: 0.27; hydrophobic: 0.4

Domains/regions: [D] Albumin 1, [D] Albumin 2, [D] Albumin 3

PDB: 1ao6, 1bj5, 1bke, 1bm0, 1e78, 1e7a, 1e7b, 1e7c, 1e7e, 1e7f, 1e7g, 1e7h, 1e7i, 1gni, 1gnj, 1h9z, 1ha2, 1hk1, 1hk2, 1hk3, 1hk4, 1hk5, 1n5u, 1o9x, 1tf0, 1uor, 2bx8, 2bxa, 2bxb, 2bxc, 2bxd, 2bxe, 2bxf, 2bxg, 2bxh, 2bxi, 2bxk, 2bxl, 2bxm, 2bxn, 2bxo, 2bxp, 2bxq, 2i2z, 2i30, 2vdb, 2vue, 2vuf, 2xsi, 2xvq, 2xvu, 2xvv, 2xvw, 2xw0, 2xw1, 2ydf, 3a73, 3b9l, 3b9m, 3cx9, 3jqz, 3jry, 3lu6, 3lu7, 3lu8, 3sqj, 3tdl, 3uiv, 4bke, 4e99, 4emx, 4g03, 4g04, 4hgk, 4hgm, 4iw1, 4iw2, 4k2c, 4k71, 4l8u, 4l9k, 4l9q, 4la0, 4lb2, 4lb9, 4n0f, 4s1y, 4z69, 5gix, 5giy, 5id7, 5ifo, 5ijf, 5ujb, 5vnw, 5x52, 5yoq, 6ezq

HET: 11d, 1fl, 308, 6a4, 9dn, 9ne, 9nf, 9nr, acd, azq, azz, b3i, c1f, c7k, dao, dif, diu, dka, fru, fud, glc, glo, hlt, ibp, idb, imn, imx, ios, ipx, lpx, myr, oca, ola, opb, p1z, p8s, pge, plm, rwf, sal, ste, swf, t44

ALBU_RABIT_25_608 Serum albumin [ALB/AFP/VDB family]

volume: 162. Å3; shape: 0.48; buriedness: 0.96

negative: 0.; positive: 0.18; polar: 0.27; backbone: 0.15; hydrophobic: 0.39

Domains/regions: [D] Albumin 3

PDB: 3v09, 4f5v, 4po0

HET: nps, pge

ALD2_MOUSE_2_316 Aldose reductase-related protein 2 [Aldo/keto reductase family]

volume: 231. Å3; shape: 0.49; buriedness: 0.87

negative: 0.; positive: 0.11; polar: 0.21; backbone: 0.05; hydrophobic: 0.63

PDB: 1c9w, 1frb

HET: zst

ALDA_ECOLI_1_479 Lactaldehyde dehydrogenase [Aldehyde dehydrogenase family]

volume: 255. Å3; shape: 0.45; buriedness: 0.6

negative: 0.15; positive: 0.; polar: 0.15; backbone: 0.12; hydrophobic: 0.58

PDB: 2hg2, 2ilu, 2imp, 2opx

HET: dxc

ALDEC_SYNE7_10_230 Aldehyde decarbonylase [Aldehyde decarbonylase family]

volume: 258. Å3; shape: 0.6; buriedness: 0.99

negative: 0.16; positive: 0.; polar: 0.2; backbone: 0.15; hydrophobic: 0.5

PDB: 4quw, 4rc5, 4rc6, 4rc7, 4rc8

HET: pl3, ste

ALDH2_HUMAN_18_517 Aldehyde dehydrogenase, mitochondrial [Aldehyde dehydrogenase family]

volume: 986. Å3; shape: 0.32; buriedness: 0.87

negative: 0.07; positive: 0.04; polar: 0.09; backbone: 0.34; hydrophobic: 0.46

PDB: 1a4z, 1ag8, 1cw3, 1nzw, 1nzx, 1nzz, 1o00, 1o01, 1o02, 1o04, 1o05, 2onn, 2ono, 2onp, 2vle, 3inj, 3inl, 3n80, 3n81, 3n82, 3n83, 3sz9, 4fqf, 4fr8, 4kwf, 4kwg, 5l13

HET: 2ak, 3ak, 6ze, adp, bxb, dzn, i3e, mg, mn, nad, nai, sm, tng

ALDOA_HUMAN_2_364 Fructose-bisphosphate aldolase A [Class I fructose-bisphosphate aldolase family]

volume: 1017. Å3; shape: 0.89; buriedness: 0.82

negative: 0.13; positive: 0.26; polar: 0.14; backbone: 0.34; hydrophobic: 0.13

PDB: 1ado, 1ald, 1ewd, 1ewe, 1ex5, 1j4e, 1zah, 1zai, 1zaj, 1zal, 2ald, 2ot0, 2ot1, 2qut, 2quu, 2quv, 3b8d, 3bv4, 3dfn, 3dfo, 3dfp, 3dfq, 3dfs, 3dft, 3lge, 3tu9, 4ald, 5f4x, 5ky6, 5tle, 5tlh, 5tlw, 5tlz, 5vy5, 6ald

HET: 13p, 2fp, 5mm, m2p, mdn, n26, n3p, rd1, rd2, rd3

ALDOB_HUMAN_2_364 Fructose-bisphosphate aldolase B [Class I fructose-bisphosphate aldolase family]

volume: 264. Å3; shape: 0.65; buriedness: 0.78

negative: 0.09; positive: 0.28; polar: 0.07; backbone: 0.48; hydrophobic: 0.07

PDB: 1fdj, 1xdl, 1xdm

HET: 13p, 2fp, g3p

ALDR_HUMAN_1_316 Aldose reductase [Aldo/keto reductase family]

volume: 400. Å3; shape: 0.74; buriedness: 0.88

negative: 0.; positive: 0.06; polar: 0.17; backbone: 0.17; hydrophobic: 0.59

PDB: 1abn, 1ads, 1az1, 1az2, 1ef3, 1el3, 1iei, 1mar, 1pwl, 1pwm, 1t40, 1t41, 1us0, 1x96, 1x97, 1x98, 1xgd, 1z3n, 1z89, 1z8a, 2acq, 2acr, 2acs, 2acu, 2agt, 2dux, 2duz, 2dv0, 2f2k, 2fz8, 2fz9, 2fzb, 2fzd, 2hv5, 2hvn, 2hvo, 2i16, 2i17, 2ikg, 2ikh, 2iki, 2ikj, 2ine, 2inz, 2ipw, 2iq0, 2iqd, 2is7, 2isf, 2j8t, 2nvc, 2nvd, 2pd5, 2pd9, 2pdb, 2pdc, 2pdf, 2pdg, 2pdh, 2pdi, 2pdj, 2pdk, 2pdl, 2pdm, 2pdn, 2pdp, 2pdq, 2pdu, 2pdw, 2pdx, 2pdy, 2pev, 2pf8, 2pfh, 2pzn, 2qxw, 2r24, 3bcj, 3dn5, 3g5e, 3ghr, 3ghs, 3ght, 3ghu, 3lbo, 3ld5, 3len, 3lep, 3lqg, 3lql, 3lz3, 3lz5, 3m0i, 3m4h, 3m64, 3mb9, 3mc5, 3onb, 3onc, 3p2v, 3q65, 3q67, 3rx2, 3rx3, 3rx4, 3s3g, 3t42, 3u2c, 3v35, 3v36, 4gca, 4igs, 4jir, 4lau, 4laz, 4lb3, 4lb4, 4lbr, 4lbs, 4nkc, 4pr4, 4prr, 4prt, 4puu, 4puw, 4q7b, 4qbx, 4qr6, 4qx4, 4qxi, 4rpq, 4xzh, 4xzi, 4ys1, 4yu1, 5ha7

HET: 1wx, 2cl, 2hz, 2w8, 2w9, 2wb, 2wq, 2wr, 2x9, 2yz, 30l, 37v, 388, 393, 3e2, 3na, 3t4, 3uh, 47d, 48i, 4g7, 4o8, 53n, 62p, 64i, alr, bfi, br, bto, doy, epr, f49, fid, fir, i84, i98, id5, ita, itb, ldt, lit, lpa, nti, ohp, pac, q74, sbi, sfi, slo, suz, tgg, tlt, tol, w8x, wy1, zes, zst

ALDR_PIG_2_316 Aldose reductase [Aldo/keto reductase family]

volume: 355. Å3; shape: 0.67; buriedness: 0.83

negative: 0.; positive: 0.08; polar: 0.15; backbone: 0.; hydrophobic: 0.77

PDB: 1ah0, 1ah3, 1ah4, 1dla, 1eko

HET: i84, sbi, tol

ALF1_THETK_1_263 Fructose-bisphosphate aldolase class 1 [DeoC/FbaB aldolase family]

volume: 190. Å3; shape: 0.68; buriedness: 0.92

negative: 0.06; positive: 0.35; polar: 0.1; backbone: 0.37; hydrophobic: 0.12

Domains/regions: [R] Substrate binding

PDB: 1ojx, 1ok4, 1ok6, 1w8s, 2yce

HET: 13p, fbp, m2p

ALF_ECOLI_1_359 Fructose-bisphosphate aldolase class 2 [Class II fructose-bisphosphate aldolase family]

volume: 102. Å3; shape: 0.54; buriedness: 0.96

negative: 0.16; positive: 0.14; polar: 0.24; backbone: 0.46; hydrophobic: 0.

Domains/regions: [R] Dihydroxyacetone phosphate binding

PDB: 1b57, 1dos, 1gyn, 1zen, 5gk3, 5gk4, 5gk5, 5gk6, 5gk7, 5gk8

HET: pgh

ALF_ENCCU_1_338 Fructose-bisphosphate aldolase [Class I fructose-bisphosphate aldolase family]

volume: 191. Å3; shape: 0.56; buriedness: 0.91

negative: 0.1; positive: 0.2; polar: 0.15; backbone: 0.41; hydrophobic: 0.15

PDB: 3mbd, 3mbf, 3qrh

HET: 2fp, g3h

ALF_HELPY_1_307 Fructose-bisphosphate aldolase [Class II fructose-bisphosphate aldolase family]

volume: 230. Å3; shape: 0.6; buriedness: 0.84

negative: 0.09; positive: 0.22; polar: 0.26; backbone: 0.43; hydrophobic: 0.

Domains/regions: [R] Dihydroxyacetone phosphate binding

PDB: 3c4u, 3c52, 3c56, 3n9r, 3n9s

HET: pgh, ph4, td3, td4

ALF_MYCTU_1_344 Fructose-bisphosphate aldolase [Class II fructose-bisphosphate aldolase family]

volume: 246. Å3; shape: 0.55; buriedness: 0.85

negative: 0.1; positive: 0.18; polar: 0.3; backbone: 0.43; hydrophobic: 0.

Domains/regions: [R] Dihydroxyacetone phosphate binding

PDB: 3ekl, 3ekz, 3elf, 4a21, 4a22, 4def, 4del, 4lv4

HET: 13p, 2fp, g3p, pgh, so4, td4

ALF_PLAF7_1_369 Fructose-bisphosphate aldolase [Class I fructose-bisphosphate aldolase family]

volume: 652. Å3; shape: 0.83; buriedness: 0.7

negative: 0.17; positive: 0.27; polar: 0.14; backbone: 0.33; hydrophobic: 0.1

PDB: 1a5c, 2eph, 2pc4, 4tr9

HET: 38d

ALF_THECA_1_305 Fructose-bisphosphate aldolase [Class II fructose-bisphosphate aldolase family]

volume: 120. Å3; shape: 0.52; buriedness: 0.96

negative: 0.13; positive: 0.14; polar: 0.25; backbone: 0.48; hydrophobic: 0.

Domains/regions: [R] Dihydroxyacetone phosphate binding

PDB: 1rv8, 1rvg, 2fjk

HET: 13p, co

ALKB5_HUMAN_68_293 RNA demethylase ALKBH5 [AlkB family]

volume: 138. Å3; shape: 0.45; buriedness: 0.58

negative: 0.; positive: 0.16; polar: 0.15; backbone: 0.29; hydrophobic: 0.4

PDB: 4nj4, 4nrm, 4nro, 4nrp, 4nrq, 4o61, 4o7x, 4oct

HET: un9

ALKB_ECOLI_10_215 Alpha-ketoglutarate-dependent dioxygenase AlkB [AlkB family]

volume: 355. Å3; shape: 0.66; buriedness: 0.97

negative: 0.06; positive: 0.24; polar: 0.3; backbone: 0.; hydrophobic: 0.4

Domains/regions: [D] Fe2OG dioxygenase, [R] Alpha-ketoglutarate binding, [R] Substrate binding

PDB: 2fd8, 2fdf, 2fdg, 2fdh, 2fdi, 2fdj, 2fdk, 3bi3, 3bie, 3bkz, 3i2o, 3i3m, 3i3q, 3i49, 3khb, 3khc, 3o1m, 3o1o, 3o1p, 3o1r, 3o1s, 3o1t, 3o1u, 3o1v, 3t3y, 3t4h, 3t4v, 4jht, 4nid, 4nig, 4nih, 4nii, 4rfr, 4zhn

HET: 8xq, md3, md5, md6, mdv, rhn

ALK_HUMAN_1090_1410 ALK tyrosine kinase receptor [Protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily]

volume: 622. Å3; shape: 0.51; buriedness: 0.77

negative: 0.07; positive: 0.03; polar: 0.; backbone: 0.51; hydrophobic: 0.38

Domains/regions: [D] Protein kinase, [R] Inhibitor binding

PDB: 2xb7, 2xba, 2xp2, 2yfx, 2yhv, 2yjr, 2yjs, 3aox, 3l9p, 3lcs, 3lct, 4anl, 4anq, 4ans, 4ccb, 4ccu, 4cd0, 4cli, 4clj, 4cmo, 4cmt, 4cmu, 4cnh, 4ctb, 4ctc, 4dce, 4fnw, 4fnx, 4fny, 4fnz, 4fob, 4foc, 4fod, 4joa, 4mkc, 4tt7, 4z55, 5a9u, 5aa8, 5aa9, 5aaa, 5aab, 5aac, 5fto, 5ftq, 5imx, 5iug, 5iuh, 5iui, 5j7h, 5kz0

HET: 0jf, 0us, 0uu, 0uv, 34y, 3dk, 3u9, 45q, 4lo, 4mk, 53p, 571, 5p8, 6gy, 6yl, 729, adp, awf, awj, cz4, emh, gui, gwh, i3k, iv7, j99, kvc, nzf, ofg, qb4, stu, u4w, vgh, ymx, ypw

ALL2_AEDAE_19_321_lipid 37 kDa salivary gland allergen Aed a 2

volume: 311. Å3; shape: 0.44; buriedness: 0.92

negative: 0.; positive: 0.11; polar: 0.26; backbone: 0.26; hydrophobic: 0.37

PDB: 3dxl, 3dy9, 3dye, 3dzt

HET: eah

ALL2_AEDAE_19_321_norepinephrine 37 kDa salivary gland allergen Aed a 2

volume: 111. Å3; shape: 0.63; buriedness: 0.99

negative: 0.2; positive: 0.1; polar: 0.2; backbone: 0.2; hydrophobic: 0.3

PDB: 3dxl, 3dy9, 3dye, 3dzt

HET: lnr

ALLC_ECOLI_1_411 Allantoate amidohydrolase [Peptidase M20 family]

volume: 102. Å3; shape: 0.69; buriedness: 0.36

negative: 0.; positive: 1.; polar: 0.; backbone: 0.; hydrophobic: 0.

PDB: 1z2l, 2imo, 4pxd

HET: 1al

ALLN1_ALLSA_39_471 Alliin lyase 1 [Alliinase family]

volume: 203. Å3; shape: 0.78; buriedness: 0.96

negative: 0.05; positive: 0.16; polar: 0.47; backbone: 0.21; hydrophobic: 0.11

PDB: 1lk9, 2hor, 2hox

HET: dha, p1t, plp

ALR1_ECOLI_2_359 Alanine racemase, biosynthetic [Alanine racemase family]

volume: 203. Å3; shape: 0.98; buriedness: 0.94

negative: 0.; positive: 0.2; polar: 0.24; backbone: 0.26; hydrophobic: 0.29

PDB: 2rjg, 2rjh, 3b8t, 3b8u, 3b8v, 3b8w, 4wr3, 4xbj

HET: dcs, in5, plp

ALR_GEOSE_1_388 Alanine racemase [Alanine racemase family]

volume: 228. Å3; shape: 0.96; buriedness: 0.96

negative: 0.; positive: 0.17; polar: 0.29; backbone: 0.29; hydrophobic: 0.25

PDB: 1bd0, 1epv, 1ftx, 1l6f, 1l6g, 1niu, 1sft, 1xqk, 1xql, 2sfp, 3uw6, 4ils

HET: 4ax, dcs, epc, in5, pdd, plp, pmh, pmp, pp3

ALR_STRCO_2_391 Alanine racemase [Alanine racemase family]

volume: 205. Å3; shape: 0.88; buriedness: 0.96

negative: 0.; positive: 0.14; polar: 0.29; backbone: 0.33; hydrophobic: 0.24

PDB: 5fac, 5fag, 5faj

HET: dcs, plp

ALSE_ECOLI_1_231 D-allulose-6-phosphate 3-epimerase [Ribulose-phosphate 3-epimerase family]

volume: 163. Å3; shape: 0.47; buriedness: 0.98

negative: 0.1; positive: 0.1; polar: 0.14; backbone: 0.45; hydrophobic: 0.22

Domains/regions: [R] Substrate binding

PDB: 3ct7, 3ctl

HET: s6p

ALTA1_ALTAL_27_157 Major allergen Alt a 1 [ALTA1 family]

volume: 82. Å3; shape: 0.9; buriedness: 0.67

negative: 0.; positive: 0.; polar: 0.67; backbone: 0.33; hydrophobic: 0.

Domains/regions: [D] AltA1

PDB: 3v0r, 4aud

HET: 0fu

ALYS_STRPN_224_318 Autolysin [N-acetylmuramoyl-L-alanine amidase 2 family]

volume: 287. Å3; shape: 0.63; buriedness: 0.67

negative: 0.13; positive: 0.; polar: 0.; backbone: 0.44; hydrophobic: 0.43

PDB: 1gvm, 1h8g, 1hcx, 2bml, 4iwt, 4x36

HET: cht, ddq, xed

AMDA_BORBO_1_240 Arylmalonate decarboxylase

volume: 95. Å3; shape: 0.6; buriedness: 0.96

negative: 0.; positive: 0.; polar: 0.22; backbone: 0.59; hydrophobic: 0.19

PDB: 2vlb, 3dg9, 3dtv, 3eis, 3ip8, 3ixl, 3ixm

HET: b85, pac

AMD_RAT_498_820 Peptidyl-glycine alpha-amidating monooxygenase

volume: 125. Å3; shape: 0.49; buriedness: 0.65

negative: 0.; positive: 0.5; polar: 0.17; backbone: 0.; hydrophobic: 0.33

Domains/regions: [R] Peptidyl-alpha-hydroxyglycine alpha- amidating lyase

PDB: 3fvz, 3fw0

HET: hh3

AMID_ECOLI_17_276_pep N-acetylmuramoyl-L-alanine amidase AmiD [N-acetylmuramoyl-L-alanine amidase 2 family]

volume: 468. Å3; shape: 0.41; buriedness: 0.59

negative: 0.13; positive: 0.25; polar: 0.06; backbone: 0.43; hydrophobic: 0.13

Domains/regions: [R] Substrate binding

PDB: 2bh7, 2wkx, 3d2y, 3d2z

HET: ah0, fga

AMNB_COMTE_1_312 2-aminophenol 1,6-dioxygenase subunit beta [LigB/MhpB extradiol dioxygenase family]

volume: 100. Å3; shape: 0.78; buriedness: 0.94

negative: 0.09; positive: 0.37; polar: 0.18; backbone: 0.05; hydrophobic: 0.31

PDB: 3vsg, 3vsh, 3vsi, 3vsj

HET: 2xp, 4nc

AMN_ECOLI_1_484 AMP nucleosidase [AMP nucleosidase family]

volume: 211. Å3; shape: 0.8; buriedness: 0.94

negative: 0.14; positive: 0.12; polar: 0.14; backbone: 0.35; hydrophobic: 0.25

PDB: 1t8r, 1t8s, 1t8w, 1t8y, 2guw

HET: fmp

AMP1_PLAFQ_195_1084 M1 family aminopeptidase [Peptidase M1 family]

volume: 367. Å3; shape: 0.54; buriedness: 0.87

negative: 0.24; positive: 0.15; polar: 0.15; backbone: 0.25; hydrophobic: 0.2

Domains/regions: [R] Substrate binding

PDB: 3ebg, 3ebh, 3ebi, 3q43, 3q44, 3t8v, 4j3b, 4k5l, 4k5m, 4k5n, 4k5o, 4k5p, 4r5t, 4r5v, 4r5x, 4x2u, 4zqt, 4zw3, 4zw5, 4zw6, 4zw7, 4zw8, 4zx3, 4zx4, 4zx5, 4zx6

HET: 19n, 1os, 1ot, 1ou, 1ov, 4qp, 4s9, 4sa, 4sy, 4sz, 4t2, 4tk, 4tl, 4tm, 4u6, bes, bey, btj, d50, d66, mg, r5t, r5v, r5x, tod

AMPA_HELPY_1_496 Cytosol aminopeptidase [Peptidase M17 family]

volume: 212. Å3; shape: 0.52; buriedness: 0.73

negative: 0.25; positive: 0.18; polar: 0.; backbone: 0.38; hydrophobic: 0.19

PDB: 4zi6, 4zla

HET: bes

AMPA_PSEPU_1_497 Cytosol aminopeptidase [Peptidase M17 family]

volume: 210. Å3; shape: 0.53; buriedness: 0.74

negative: 0.2; positive: 0.14; polar: 0.03; backbone: 0.31; hydrophobic: 0.32

PDB: 3h8e, 3h8f, 3h8g

HET: bes

AMPC_CITFR_21_381 Beta-lactamase [Class-C beta-lactamase family]

volume: 247. Å3; shape: 0.64; buriedness: 0.7

negative: 0.; positive: 0.07; polar: 0.43; backbone: 0.44; hydrophobic: 0.06

Domains/regions: [R] Substrate binding

PDB: 1fr1, 1fr6, 1rgy, 1zc2

HET: azr, ptx

AMPC_ECOLI_20_377 Beta-lactamase [Class-C beta-lactamase family]

volume: 454. Å3; shape: 0.65; buriedness: 0.71

negative: 0.; positive: 0.05; polar: 0.31; backbone: 0.44; hydrophobic: 0.19

Domains/regions: [R] Substrate binding

PDB: 1c3b, 1fcm, 1fcn, 1fco, 1fsw, 1fsy, 1ga9, 1i5q, 1iel, 1iem, 1kds, 1kdw, 1ke0, 1ke3, 1ke4, 1kvl, 1kvm, 1l0d, 1l0e, 1l0f, 1l0g, 1l2s, 1ll5, 1ll9, 1llb, 1mxo, 1my8, 1o07, 1pi4, 1pi5, 1xgi, 1xgj, 2bls, 2ffy, 2hdq, 2hdr, 2hds, 2hdu, 2i72, 2p9v, 2pu2, 2pu4, 2r9w, 2r9x, 2rcx, 2zj9, 3bls, 3bm6, 3fkv, 3fkw, 3gqz, 3gr2, 3grj, 3gsg, 3gtc, 3gv9, 3gvb, 3iwi, 3iwo, 3iwq, 3ixb, 3ixd, 3ixg, 3ixh, 3o86, 3o87, 3o88, 4e3i, 4e3j, 4e3k, 4e3l, 4e3m, 4e3n, 4e3o, 4jxg, 4jxs, 4jxv, 4jxw, 4ken, 4kg2, 4kg5, 4kg6, 4kz3, 4kz4, 4kz5, 4kz6, 4kz7, 4kz8, 4kz9, 4kza, 4kzb, 4lv0, 4lv1, 4lv2, 4lv3, 4okp, 4old, 4olg, 5f1g, 5ggw, 5gzw, 5joc

HET: 0n3, 0n4, 0na, 0nb, 0nd, 0ne, 0ng, 105, 1mu, 1mw, 1s6, 1s7, 1u1, 1u3, 1u5, 1u6, 23c, 25n, 2tv, 2uz, 3gv, 4a3, 4cb, 4mb, amp, apb, bdb, bsf, bsg, bsh, bzb, c9p, caz, cb4, cls, ctb, cvb, cxu, dk2, etp, f12, gf1, gf4, gf7, gtc, gv9, htc, im2, lor, mox, mxg, n95, nl9, npb, nz2, nz9, ox6, pcz, po4, sm2, sm3, sm4, stc, suc, va1, wh6

AMPC_ENTCL_21_381 Beta-lactamase [Class-C beta-lactamase family]

volume: 343. Å3; shape: 0.65; buriedness: 0.69

negative: 0.; positive: 0.05; polar: 0.41; backbone: 0.38; hydrophobic: 0.15

Domains/regions: [R] Substrate binding

PDB: 1bls, 1ga0, 1gce, 1onh, 1q2q, 1rgz, 1s6r, 1xx2, 1y54, 2q9m, 2q9n, 3s4x, 4xux, 5hai, 5xhr

HET: 4d6, dvr, fdt, iap, ipp, lk5, lk7, ptx, pxh, wy2, wy4

AMPC_PSEAE_28_392 Beta-lactamase [Class-C beta-lactamase family]

volume: 269. Å3; shape: 0.47; buriedness: 0.8

negative: 0.; positive: 0.1; polar: 0.49; backbone: 0.34; hydrophobic: 0.06

Domains/regions: [R] Substrate binding

PDB: 2wzx, 2wzz, 3s1y, 3s22, 4gzb, 4hef, 4nk3, 4ooy, 4wyy, 4wz4, 4x68

HET: 3s2, 3vt, 3vu, mk7, nxl, op0, s1y, zx0, zx1

AMPD_CITFR_1_187 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD [N-acetylmuramoyl-L-alanine amidase 2 family]

volume: 305. Å3; shape: 0.51; buriedness: 0.69

negative: 0.06; positive: 0.32; polar: 0.06; backbone: 0.37; hydrophobic: 0.18

PDB: 2y28, 2y2b, 2y2c, 2y2d, 2y2e

HET: mhi

[<<] entries 101–200 [>>]