[POCKETOME]
 

Search Results

3313 entries [expand]
Show only: ⁠Human; ⁠Other mammals; ⁠Gram-positive bacteria; ⁠Gram-negative bacteria; ⁠Archaea; ⁠Virus; ⁠Other.
entries 1–100 [>>]

1433B_HUMAN_1_240_pep 14-3-3 protein beta/alpha [14-3-3 family]

volume: 1392. Å3; shape: 0.42; buriedness: 0.58

negative: 0.12; positive: 0.28; polar: 0.24; backbone: 0.07; hydrophobic: 0.29

PDB: 2bq0, 2c23, 4dnk, 4gnt, 5f74, 5n10

HET: amp, tpo

1433C_TOBAC_1_256 14-3-3-like protein C [14-3-3 family]

volume: 705. Å3; shape: 0.74; buriedness: 0.61

negative: 0.08; positive: 0.15; polar: 0.15; backbone: 0.2; hydrophobic: 0.42

PDB: 1o9c, 1o9d, 1o9e, 1o9f, 2o98, 3e6y, 3m50, 3m51, 5nwi, 5nwj, 5nwk

HET: cw1, ebt, fsc, yr1

1433F_HUMAN_1_246_pep 14-3-3 protein eta [14-3-3 family]

volume: 426. Å3; shape: 0.61; buriedness: 0.51

negative: 0.; positive: 0.29; polar: 0.31; backbone: 0.; hydrophobic: 0.4

PDB: 2c63, 2c74, 5yqg

HET: sep

1433S_HUMAN_1_233 14-3-3 protein sigma [14-3-3 family]

volume: 1556. Å3; shape: 0.43; buriedness: 0.58

negative: 0.06; positive: 0.17; polar: 0.22; backbone: 0.22; hydrophobic: 0.33

PDB: 1ywt, 1yz5, 3iqj, 3iqu, 3iqv, 3lw1, 3mhr, 3o8i, 3p1n, 3p1o, 3p1p, 3p1q, 3p1r, 3p1s, 3smk, 3sml, 3smm, 3smn, 3smo, 3sp5, 3spr, 3t0l, 3t0m, 3u9x, 3ux0, 4dat, 4dau, 4dhm, 4dhn, 4dho, 4dhp, 4dhq, 4dhr, 4dhs, 4dht, 4dhu, 4fl5, 4fr3, 4iea, 4jc3, 4jdd, 4qli, 4y32, 4y3b, 4y5i, 5btv, 5hf3, 5lu1, 5lu2, 5mhc, 5moc, 5mxo, 5my9, 5myc, 5n5r, 5n5t, 5n5w, 5n75, 5oeg, 5oeh, 5ok9, 5okf, 5om0, 6fbb, 6fcp

HET: 0dv, 0kb, 0kc, 0kg, 0kh, 0v4, 1ct, 2ct, 49f, 60h, ace, ca, cd, cw7, cx7, fc7, fja, fsc, fw1, m1t, mg, pip, plp, sep, tpo, y03, y04, y06, y07, y09

1433Z_HUMAN_1_244_pep 14-3-3 protein zeta/delta [14-3-3 family]

volume: 2578. Å3; shape: 0.59; buriedness: 0.52

negative: 0.09; positive: 0.22; polar: 0.19; backbone: 0.15; hydrophobic: 0.35

PDB: 1a38, 1a4o, 1ib1, 1qja, 1qjb, 2c1j, 2c1n, 2o02, 2v7d, 2wh0, 3cu8, 3nkx, 3rdh, 4bg6, 4fj3, 4hkc, 4ihl, 4n7g, 4n7y, 4n84, 4wrq, 4zdr, 5d2d, 5d3f, 5ewz, 5exa, 5j31, 5jm4, 5m35, 5m36, 5m37, 5nas, 5ulo, 5wxn, 6ejl, 6eww, 6f08, 6f09

HET: 1f5, 2jn, 3rd, 5so, 6l9, a1g, aly, far, fsc, k, lpd, mg, mk8, mkd, p6g, pe4, sep, tpo, zs8

1A02_HUMAN_25_199_pep HLA class I histocompatibility antigen, A-2 alpha chain [MHC class I family]

volume: 1870. Å3; shape: 0.65; buriedness: 0.72

negative: 0.06; positive: 0.13; polar: 0.38; backbone: 0.15; hydrophobic: 0.29

Domains/regions: [R] Alpha-1, [R] Alpha-2

PDB: 1akj, 1ao7, 1b0g, 1b0r, 1bd2, 1duy, 1duz, 1eey, 1eez, 1hhg, 1hhh, 1hhi, 1hhj, 1hhk, 1hla, 1i1f, 1i1y, 1i4f, 1i7r, 1i7t, 1i7u, 1im3, 1jf1, 1jht, 1lp9, 1oga, 1p7q, 1qew, 1qr1, 1qrn, 1qse, 1qsf, 1s8d, 1s9w, 1s9x, 1s9y, 1t1w, 1t1x, 1t1y, 1t1z, 1t20, 1t21, 1t22, 1tvb, 1tvh, 2av1, 2av7, 2bnq, 2bnr, 2c7u, 2clr, 2f53, 2f54, 2git, 2gj6, 2gt9, 2gtw, 2gtz, 2guo, 2j8u, 2jcc, 2p5e, 2p5w, 2pye, 2uwe, 2v2w, 2v2x, 2vlj, 2vlk, 2vll, 2vlr, 2x4n, 2x4o, 2x4p, 2x4q, 2x4r, 2x4s, 2x4t, 2x4u, 2x70, 3bgm, 3bh8, 3bh9, 3bhb, 3d25, 3d39, 3d3v, 3fqn, 3fqr, 3fqt, 3fqu, 3fqw, 3fqx, 3ft2, 3ft3, 3ft4, 3giv, 3gjf, 3gsn, 3gso, 3gsq, 3gsr, 3gsu, 3gsv, 3gsw, 3gsx, 3h7b, 3h9h, 3h9s, 3hae, 3hg1, 3hla, 3hpj, 3i6g, 3i6k, 3ixa, 3kla, 3mgo, 3mgt, 3mr9, 3mrb, 3mrc, 3mrd, 3mre, 3mrf, 3mrg, 3mrh, 3mri, 3mrj, 3mrk, 3mrl, 3mrm, 3mrn, 3mro, 3mrp, 3mrq, 3mrr, 3myj, 3o3a, 3o3b, 3o3d, 3o3e, 3o4l, 3ox8, 3oxr, 3oxs, 3pwj, 3pwl, 3pwn, 3pwp, 3qdg, 3qdj, 3qdm, 3qeq, 3qfd, 3qfj, 3rew, 3to2, 3utq, 3uts, 3utt, 3v5d, 3v5h, 3v5k, 4e5x, 4eup, 4ftv, 4gkn, 4gks, 4i4w, 4jfd, 4jfe, 4jff, 4jfo, 4jfp, 4jfq, 4k7f, 4l3e, 4mnq, 4nnx, 4nny, 4no0, 4no2, 4no3, 4no5, 4qok, 4u6x, 4u6y, 4uq3, 4wj5, 4wuu, 5c07, 5c08, 5c09, 5c0a, 5c0b, 5c0c, 5c0d, 5c0e, 5c0f, 5c0g, 5c0i, 5c0j, 5d2n, 5d9s, 5ddh, 5e00, 5e9d, 5enw, 5eot, 5eu3, 5eu4, 5eu5, 5eu6, 5euo, 5f7d, 5f9j, 5fa3, 5fa4, 5fdw, 5hhm, 5hhn, 5hho, 5hhp, 5hhq, 5hyj, 5iro, 5isz, 5jhd, 5jzi, 5men, 5meo, 5mep, 5meq, 5mer, 5n1y, 5n6b, 5nme, 5nmf, 5nmg, 5nmh, 5nmk, 5swq, 5tez, 5wsh

HET: 3ib, cde, grn, lph, mse, na, nva, prq, prv, prw, xfw, xy1

1A12_SOLLC_11_438 1-aminocyclopropane-1-carboxylate synthase 2 [Class-I pyridoxal-phosphate-dependent aminotransferase family]

volume: 109. Å3; shape: 0.63; buriedness: 0.56

negative: 0.; positive: 0.28; polar: 0.12; backbone: 0.24; hydrophobic: 0.36

PDB: 1iax, 1iay

HET: avg

1A1C_MALDO_2_433 1-aminocyclopropane-1-carboxylate synthase [Class-I pyridoxal-phosphate-dependent aminotransferase family]

volume: 402. Å3; shape: 0.63; buriedness: 0.92

negative: 0.05; positive: 0.18; polar: 0.38; backbone: 0.17; hydrophobic: 0.22

PDB: 1b8g, 1m4n, 1m7y, 1ynu, 3piu

HET: aad, mrd, plp, plr, ppg, py4

1A1D_CYBSA_1_341 1-aminocyclopropane-1-carboxylate deaminase [ACC deaminase/D-cysteine desulfhydrase family]

volume: 240. Å3; shape: 0.86; buriedness: 0.99

negative: 0.04; positive: 0.06; polar: 0.33; backbone: 0.51; hydrophobic: 0.05

PDB: 1f2d, 1j0c, 1j0d, 1j0e

HET: 1ac, 5pa, plp

1B08_HUMAN_25_300_pep HLA class I histocompatibility antigen, B-8 alpha chain [MHC class I family]

volume: 1734. Å3; shape: 0.68; buriedness: 0.74

negative: 0.12; positive: 0.05; polar: 0.56; backbone: 0.1; hydrophobic: 0.17

Domains/regions: [R] Alpha-1, [R] Alpha-2

PDB: 1agb, 1agc, 1agd, 1age, 1agf, 1m05, 1mi5, 3ffc, 3sjv, 3skm, 3sko, 3spv, 3x13, 3x14, 4qrp, 4qrq, 4qrs, 4qrt, 4qru

1B57_HUMAN_24_300 HLA class I histocompatibility antigen, B-57 alpha chain [MHC class I family]

volume: 1240. Å3; shape: 0.48; buriedness: 0.74

negative: 0.07; positive: 0.03; polar: 0.5; backbone: 0.11; hydrophobic: 0.3

Domains/regions: [R] Alpha-1, [R] Alpha-2

PDB: 2bvo, 2bvp, 2bvq, 2hjk, 2hjl, 2rfx, 2ypk, 2ypl, 3upr, 3vh8, 3vri, 3vrj, 3wuw, 3x11, 3x12, 5b38, 5b39, 5t6w, 5t6x, 5t6y, 5t6z, 5t70, 5u98, 5v5m, 6bxp, 6bxq

HET: 1kx, kyn

3HAO_CUPMC_1_173 3-hydroxyanthranilate 3,4-dioxygenase [3-HAO family]

volume: 118. Å3; shape: 0.68; buriedness: 0.92

negative: 0.26; positive: 0.5; polar: 0.; backbone: 0.; hydrophobic: 0.24

PDB: 1yfu, 1yfw, 1yfx, 1yfy, 4hsj, 4hsl, 4hvo, 4hvq, 4hvr, 4i3p, 4l2n, 4r52, 4wzc, 5v26, 5v27, 5v28

HET: 1cw, 1uc, 3ha, 4aa, 6pc, sal

3MG2_ECOLI_1_282 DNA-3-methyladenine glycosylase 2 [Alkylbase DNA glycosidase AlkA family]

volume: 335. Å3; shape: 0.56; buriedness: 0.41

negative: 0.08; positive: 0.; polar: 0.26; backbone: 0.46; hydrophobic: 0.2

PDB: 1diz, 1mpg, 1pvs, 3cvs, 3cvt, 3cw7, 3cwa, 3cws, 3cwt, 3cwu, 3d4v, 3ogd, 3oh6, 3oh9

HET: 7hp, 8og, nri

3SA3_NAJAT_22_81_SGC Cytotoxin 3 [Snake three-finger toxin family. Short- chain subfamily. Type IA cytotoxin sub-subfamily]

volume: 2641. Å3; shape: 0.65; buriedness: 0.22

negative: 0.; positive: 0.19; polar: 0.1; backbone: 0.44; hydrophobic: 0.27

PDB: 1h0j, 1xt3, 2bhi

HET: c10, ids, sds, sft, sgn

4CL2_TOBAC_1_542 4-coumarate--CoA ligase 2 [ATP-dependent AMP-binding enzyme family]

volume: 360. Å3; shape: 0.92; buriedness: 0.97

negative: 0.05; positive: 0.1; polar: 0.23; backbone: 0.39; hydrophobic: 0.23

PDB: 5bsm, 5bsr, 5bst, 5bsu, 5bsv, 5bsw, 5u95

HET: 4uu, 4uv, 4uw, amp, atp, mg

4OT_BACSU_2_62 2-hydroxymuconate tautomerase [4-oxalocrotonate tautomerase family]

volume: 120. Å3; shape: 0.58; buriedness: 0.68

negative: 0.; positive: 0.18; polar: 0.12; backbone: 0.35; hydrophobic: 0.35

Domains/regions: [R] Substrate binding

PDB: 2op8, 2opa

HET: fhc

5EAS_TOBAC_2_548 5-epi-aristolochene synthase [Terpene synthase family]

volume: 367. Å3; shape: 0.71; buriedness: 0.9

negative: 0.13; positive: 0.11; polar: 0.27; backbone: 0.21; hydrophobic: 0.28

PDB: 1hx9, 1hxa, 1hxc, 1hxg, 3lz9, 3m00, 3m01, 3m02, 4di5, 4rnq, 5dhi, 5dhk, 5eas, 5eat, 5eau, 5ik0, 5ik6, 5ik9, 5ika, 5ikh, 5il3, 5il8, 5ild, 5ilh, 5ili, 5ilj, 5ilk, 5ily, 5ilz, 5im1

HET: 1ga, 2cf, 3cx, 3fx, 6bw, 6bx, 6by, a4s, b3p, btb, cre, dpo, far, fff, fhp, fjp, fpf, fpp, mg

5HT1B_HUMAN_31_390 5-hydroxytryptamine receptor 1B [G-protein coupled receptor 1 family]

volume: 376. Å3; shape: 0.55; buriedness: 0.89

negative: 0.1; positive: 0.; polar: 0.12; backbone: 0.27; hydrophobic: 0.51

Domains/regions: [R] Agonist binding

PDB: 4iaq, 4iar

HET: 2gm, erm

5HT2B_HUMAN_27_404 5-hydroxytryptamine receptor 2B [G-protein coupled receptor 1 family]

volume: 421. Å3; shape: 0.66; buriedness: 0.93

negative: 0.07; positive: 0.; polar: 0.19; backbone: 0.28; hydrophobic: 0.47

Domains/regions: [R] Agonist binding

PDB: 4ib4, 4nc3, 5tud, 5tvn

HET: 7ld, erm

5HT2C_HUMAN_39_393 5-hydroxytryptamine receptor 2C [G-protein coupled receptor 1 family]

volume: 496. Å3; shape: 0.62; buriedness: 0.9

negative: 0.05; positive: 0.; polar: 0.24; backbone: 0.34; hydrophobic: 0.37

Domains/regions: [R] Agonist binding

PDB: 6bqg, 6bqh

HET: e2j, erm

5NTC_HUMAN_1_536 Cytosolic purine 5'-nucleotidase [5'(3')-deoxyribonucleotidase family]

volume: 228. Å3; shape: 0.63; buriedness: 0.7

negative: 0.05; positive: 0.04; polar: 0.1; backbone: 0.46; hydrophobic: 0.36

PDB: 2j2c, 2jc9, 2jcm, 2xcv, 2xcw, 2xcx, 2xjb, 2xjc, 2xjd, 2xje, 2xjf, 4h4b, 5cqz, 5cr7, 5k7y, 5l4z, 5l50

HET: 5wo

5NTD_HUMAN_24_549 5'-nucleotidase [5'-nucleotidase family]

volume: 401. Å3; shape: 0.65; buriedness: 0.68

negative: 0.19; positive: 0.26; polar: 0.1; backbone: 0.27; hydrophobic: 0.17

Domains/regions: [R] Substrate binding

PDB: 4h1s, 4h1y, 4h2b, 4h2f, 4h2g, 4h2i

HET: 0xe, 0yq, a12, adn, zn

6PGD_ECOLI_1_468 6-phosphogluconate dehydrogenase, decarboxylating [6-phosphogluconate dehydrogenase family]

volume: 146. Å3; shape: 0.52; buriedness: 0.93

negative: 0.08; positive: 0.39; polar: 0.24; backbone: 0.14; hydrophobic: 0.14

Domains/regions: [R] Substrate binding

PDB: 2zya, 2zyd, 2zyg, 3fwn

HET: 6pg, glo

6PGD_HUMAN_1_476 6-phosphogluconate dehydrogenase, decarboxylating [6-phosphogluconate dehydrogenase family]

volume: 821. Å3; shape: 0.41; buriedness: 0.75

negative: 0.03; positive: 0.2; polar: 0.2; backbone: 0.4; hydrophobic: 0.17

Domains/regions: [R] Substrate binding

PDB: 1pgn, 1pgo, 1pgp, 1pgq, 2jkv, 2pgd, 4gwg, 4gwk

HET: 3pg, 6pg, nap, nbp, ndp

6PGD_LACLM_1_472 6-phosphogluconate dehydrogenase, decarboxylating [6-phosphogluconate dehydrogenase family]

volume: 143. Å3; shape: 0.52; buriedness: 0.72

negative: 0.14; positive: 0.45; polar: 0.41; backbone: 0.; hydrophobic: 0.

Domains/regions: [R] Substrate binding

PDB: 2iyo, 2iyp, 2iz0, 2iz1

HET: 5rp, 6pg, res

7OMT8_MEDSA_1_352 Isoflavone-7-O-methyltransferase 8 [Class I-like SAM-binding methyltransferase superfamily. Cation-independent O- methyltransferase family. COMT subfamily]

volume: 196. Å3; shape: 0.42; buriedness: 0.9

negative: 0.; positive: 0.06; polar: 0.26; backbone: 0.29; hydrophobic: 0.39

Domains/regions: [R] Substrate binding

PDB: 1fp2, 6cig

HET: hmo

8ODP_HUMAN_42_197 7,8-dihydro-8-oxoguanine triphosphatase [Nudix hydrolase family]

volume: 361. Å3; shape: 0.73; buriedness: 0.91

negative: 0.1; positive: 0.; polar: 0.12; backbone: 0.3; hydrophobic: 0.48

Domains/regions: [D] Nudix hydrolase, [R] Substrate binding

PDB: 3q93, 3whw, 3zr0, 3zr1, 4c9w, 4c9x, 4n1t, 4n1u, 5ans, 5ant, 5anu, 5anv, 5anw, 5fsi, 5fsk, 5fsl, 5fsm, 5fsn, 5fso, 5ghi, 5ghj, 5ghm, 5ghn, 5gho, 5ghp, 5ghq, 5mzf, 5ngr, 5ngs, 5ngt, 5nhy, 5ws7, 6f1x, 6f20, 6f22, 6f23

HET: 2gd, 2ge, 58t, 6q3, 6u4, 8dg, 8og, 8wt, 8ww, 8wz, 8xt, 9cq, c8z, c9b, c9e, c9q, h6y, n91, na, rgj, rje, rux, rx8, s76, uan, vgh, vhs

8ODP_MOUSE_2_156 7,8-dihydro-8-oxoguanine triphosphatase [Nudix hydrolase family]

volume: 231. Å3; shape: 0.51; buriedness: 0.94

negative: 0.14; positive: 0.07; polar: 0.14; backbone: 0.19; hydrophobic: 0.47

Domains/regions: [D] Nudix hydrolase, [R] Substrate binding

PDB: 5mze, 5mzg, 6ehh

HET: 2ge, 8dg

A1AG2_HUMAN_18_201 Alpha-1-acid glycoprotein 2 [Calycin superfamily. Lipocalin family]

volume: 250. Å3; shape: 0.89; buriedness: 0.92

negative: 0.08; positive: 0.11; polar: 0.12; backbone: 0.23; hydrophobic: 0.45

PDB: 3apu, 3apv, 3apw, 3apx

HET: dp0, pg4, tp0, z80

A1HB2_LOXIN_17_302 Phospholipase D LiSicTox-alphaIA1bii [Arthropod phospholipase D family. Class II subfamily]

volume: 130. Å3; shape: 0.55; buriedness: 0.87

negative: 0.31; positive: 0.22; polar: 0.28; backbone: 0.; hydrophobic: 0.19

Domains/regions: [D] GDPD

PDB: 3rlg, 4rw3, 4rw5

HET: ipd, oca

AA1R_HUMAN_1_312 Adenosine receptor A1 [G-protein coupled receptor 1 family]

volume: 400. Å3; shape: 0.71; buriedness: 0.78

negative: 0.06; positive: 0.02; polar: 0.35; backbone: 0.04; hydrophobic: 0.54

PDB: 5n2s, 5uen

HET: 8k8, du1

AA2AR_HUMAN_1_315_Galpha Adenosine receptor A2a [G-protein coupled receptor 1 family]

volume: 1210. Å3; shape: 0.77; buriedness: 0.43

negative: 0.03; positive: 0.11; polar: 0.16; backbone: 0.49; hydrophobic: 0.21

PDB: 2ydo, 2ydv, 3eml, 3pwh, 3qak, 3rey, 3rfm, 3uza, 3uzc, 3vg9, 3vga, 4eiy, 4ug2, 4uhr, 5g53, 5iu4, 5iu7, 5iu8, 5iua, 5iub, 5jtb, 5k2a, 5k2b, 5k2c, 5k2d, 5mzj, 5mzp, 5n2r, 5nlx, 5nm2, 5nm4, 5olg, 5olh, 5olo, 5olv, 5olz, 5om1, 5om4, 5uig, 5uvi, 5vra, 5wf5, 5wf6, 6aqf

AA2AR_HUMAN_1_315_TM Adenosine receptor A2a [G-protein coupled receptor 1 family]

volume: 847. Å3; shape: 0.81; buriedness: 0.75

negative: 0.05; positive: 0.13; polar: 0.22; backbone: 0.1; hydrophobic: 0.5

Domains/regions: [R] Agonist binding

PDB: 2ydo, 2ydv, 3eml, 3pwh, 3qak, 3rey, 3rfm, 3uza, 3uzc, 3vg9, 3vga, 4eiy, 4ug2, 4uhr, 5g53, 5iu4, 5iu7, 5iu8, 5iua, 5iub, 5jtb, 5k2a, 5k2b, 5k2c, 5k2d, 5mzj, 5mzp, 5n2r, 5nlx, 5nm2, 5nm4, 5olg, 5olh, 5olo, 5olv, 5olz, 5om1, 5om4, 5uig, 5uvi, 5vra, 5wf5, 5wf6, 6aqf

HET: 6dv, 6dx, 6dy, 6dz, 8d1, 8jn, 9xt, 9xw, 9y2, adn, cff, nec, ngi, ola, olc, pge, t4e, t4g, tep, uka, xac, zma

AAAA_PENCH_1_357 Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form [Peptidase C45 family]

volume: 107. Å3; shape: 0.77; buriedness: 0.86

negative: 0.; positive: 0.11; polar: 0.11; backbone: 0.59; hydrophobic: 0.2

PDB: 2x1c, 2x1d, 2x1e

HET: x1e

AACL1_BRADU_2_326 Amino acid--[acyl-carrier-protein] ligase 1 [Class-II aminoacyl-tRNA synthetase family. Amino acid--[acyl-carrier-protein] ligase subfamily]

volume: 736. Å3; shape: 0.35; buriedness: 0.79

negative: 0.09; positive: 0.17; polar: 0.16; backbone: 0.3; hydrophobic: 0.28

PDB: 3mey, 3mf1, 3mf2, 3pzc, 4h2s, 4h2t, 4h2u, 4h2v, 4h2w, 4h2x, 4h2y

HET: 5gp, amp, atp, coa, g5a, gap, h2v, mg, pns

AADAT_HUMAN_1_425 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [Class-I pyridoxal-phosphate-dependent aminotransferase family]

volume: 862. Å3; shape: 0.39; buriedness: 0.96

negative: 0.03; positive: 0.12; polar: 0.31; backbone: 0.25; hydrophobic: 0.29

PDB: 2qlr, 2r2n, 2vgz, 2xh1, 3dc1, 3ue8, 4gdy, 4ge4, 4ge7, 4ge9, 4geb, 5efs, 5eun, 5tf5

HET: 09m, 0k5, 0ke, 0l0, 0ld, 0x1, 7ar, bf5, kyn, plp, pmp

AAK1_HUMAN_28_358 AP2-associated protein kinase 1 [Protein kinase superfamily. Ser/Thr protein kinase family]

volume: 452. Å3; shape: 0.51; buriedness: 0.8

negative: 0.09; positive: 0.05; polar: 0.1; backbone: 0.33; hydrophobic: 0.43

Domains/regions: [D] Protein kinase

PDB: 4wsq, 5l4q, 5te0

HET: ksa, lkb, xin

AAKB1_HUMAN_70_159 5'-AMP-activated protein kinase subunit beta-1 [5'-AMP-activated protein kinase beta subunit family]

volume: 1263. Å3; shape: 0.78; buriedness: 0.35

negative: 0.11; positive: 0.09; polar: 0.23; backbone: 0.3; hydrophobic: 0.26

Domains/regions: [R] Glycogen-binding domain

PDB: 1z0m, 1z0n, 4cfe, 4qfg, 4qfr, 4yef, 4zhx, 5ezv, 5iso, 5kq5, 5t5t, 5ufu

HET: 32j, 4cq, 6vt, 75o, 85v, 992, c1v

AAKG1_HUMAN_182_330 5'-AMP-activated protein kinase subunit gamma-1 [5'-AMP-activated protein kinase gamma subunit family]

volume: 336. Å3; shape: 0.53; buriedness: 0.84

negative: 0.06; positive: 0.16; polar: 0.24; backbone: 0.31; hydrophobic: 0.23

Domains/regions: [D] CBS 2, [D] CBS 3, [D] CBS 4

PDB: 2uv4, 2uv5, 2uv6, 2uv7, 2v8q, 2v92, 2v9j, 2y8l, 2y8q, 2ya3, 4cfe, 4cfh, 4eag, 4eai, 4eaj, 4eak, 4eal, 4qfg, 4qfr, 4zhx, 5ezv, 5iso, 5kq5, 5t5t, 5ufu

HET: amp, amz, atp, c2z

AAKG1_HUMAN_4_182 5'-AMP-activated protein kinase subunit gamma-1 [5'-AMP-activated protein kinase gamma subunit family]

volume: 363. Å3; shape: 0.4; buriedness: 0.87

negative: 0.05; positive: 0.2; polar: 0.2; backbone: 0.34; hydrophobic: 0.21

Domains/regions: [D] CBS 1, [D] CBS 2, [D] CBS 3, [D] CBS 4

PDB: 4cfe, 4eag, 4eak, 4eal, 4qfg, 4qfr, 4zhx, 5ezv, 5iso, 5kq5, 5t5t, 5ufu

HET: adp, amp, atp, c2z

AAPK1_HUMAN_14_295 5'-AMP-activated protein kinase catalytic subunit alpha-1 [Protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily]

volume: 352. Å3; shape: 0.54; buriedness: 0.53

negative: 0.1; positive: 0.25; polar: 0.1; backbone: 0.18; hydrophobic: 0.37

Domains/regions: [D] Protein kinase

PDB: 4cfh, 4qfg, 4qfr, 4red, 5kq5, 5t5t, 5ufu

HET: 32j, 6vt, 75o, 85v

AAPK2_HUMAN_2_280_ATPsite 5'-AMP-activated protein kinase catalytic subunit alpha-2 [Protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily]

volume: 413. Å3; shape: 0.57; buriedness: 0.87

negative: 0.1; positive: 0.04; polar: 0.07; backbone: 0.41; hydrophobic: 0.38

Domains/regions: [D] Protein kinase

PDB: 2h6d, 2yza, 3aqv, 4cfe, 4zhx, 5ezv, 5iso

HET: 4o7, stu, tak

AAPK2_HUMAN_2_280_beta 5'-AMP-activated protein kinase catalytic subunit alpha-2 [Protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily]

volume: 289. Å3; shape: 0.48; buriedness: 0.55

negative: 0.12; positive: 0.19; polar: 0.09; backbone: 0.22; hydrophobic: 0.38

Domains/regions: [D] Protein kinase

PDB: 2h6d, 2yza, 3aqv, 4cfe, 4zhx, 5ezv, 5iso

HET: 992, c1v

AASS_HUMAN_453_926 Alpha-aminoadipic semialdehyde synthase, mitochondrial

volume: 114. Å3; shape: 0.64; buriedness: 0.72

negative: 0.15; positive: 0.15; polar: 0.26; backbone: 0.3; hydrophobic: 0.13

Domains/regions: [R] Saccharopine binding, [R] Saccharopine dehydrogenase

PDB: 5l76, 5l78, 5o1n, 5o1o, 5o1p

HET: 9h8

AATC_HUMAN_4_413 Aspartate aminotransferase, cytoplasmic [Class-I pyridoxal-phosphate-dependent aminotransferase family]

volume: 248. Å3; shape: 0.85; buriedness: 0.96

negative: 0.05; positive: 0.19; polar: 0.35; backbone: 0.23; hydrophobic: 0.17

PDB: 1ajr, 1ajs, 3ii0, 3wzf, 5ton, 5toq, 5tor, 5tot, 5vjz, 5vk7

HET: pla, plp, tar

AAT_ECOLI_1_396 Aspartate aminotransferase [Class-I pyridoxal-phosphate-dependent aminotransferase family]

volume: 294. Å3; shape: 0.87; buriedness: 0.96

negative: 0.05; positive: 0.18; polar: 0.33; backbone: 0.2; hydrophobic: 0.24

PDB: 1aam, 1aaw, 1ahe, 1ahf, 1ahg, 1ahx, 1ahy, 1aia, 1aib, 1aic, 1amq, 1amr, 1ams, 1arg, 1arh, 1ari, 1ars, 1art, 1asa, 1asb, 1asc, 1asd, 1ase, 1asf, 1asg, 1asl, 1asm, 1asn, 1b4x, 1bqa, 1bqd, 1c9c, 1cq6, 1cq7, 1cq8, 1czc, 1cze, 1g4v, 1g4x, 1g7w, 1g7x, 1ix6, 1ix7, 1ix8, 1qir, 1qis, 1qit, 1spa, 1toe, 1tog, 1toi, 1toj, 1tok, 1x28, 1x29, 1x2a, 1yoo, 2aat, 2d5y, 2d61, 2d63, 2d64, 2d65, 2d66, 2d7y, 2d7z, 2q7w, 2qa3, 2qb2, 2qb3, 2qbt, 3aat, 3pa9, 3paa, 3qn6, 3qpg, 3uak, 3zzj, 3zzk, 4a00, 4dbc, 4f5f, 4f5g, 4f5h, 4f5i, 4f5j, 4f5k, 4f5l, 4f5m, 5eaa, 5t4l, 5vwq, 5vwr

HET: 0a0, 77e, hci, iop, iva, mae, mpl, nop, npl, pdg, pgu, pj7, pl6, pla, plp, pmg, pmp, pp3, ppd, psz, py4, py5, py6

AATM_CHICK_23_423 Aspartate aminotransferase, mitochondrial [Class-I pyridoxal-phosphate-dependent aminotransferase family]

volume: 244. Å3; shape: 0.97; buriedness: 0.91

negative: 0.06; positive: 0.16; polar: 0.32; backbone: 0.18; hydrophobic: 0.28

PDB: 1aka, 1akb, 1akc, 1ama, 1ivr, 1map, 1maq, 1oxo, 1oxp, 1tar, 1tas, 1tat, 7aat, 8aat, 9aat

HET: cba, ik2, ket, pgu, pla, plp, pmp, ppd, ppe

AAUA_ALCFA_57_182 Aralkylamine dehydrogenase light chain [Aromatic amine dehydrogenase light chain family]

volume: 141. Å3; shape: 0.63; buriedness: 1.

negative: 0.13; positive: 0.; polar: 0.16; backbone: 0.45; hydrophobic: 0.26

Multimer with: Aralkylamine dehydrogenase heavy chain (AAUB_ALCFA) [Aromatic amine dehydrogenase heavy chain family]
Domains/regions (AAUA): [R] Substrate-binding

PDB: 2agl, 2agw, 2agx, 2agy, 2agz, 2ah0, 2ah1, 2h3x, 2h47, 2hj4, 2hjb, 2hkm, 2hkr, 2hxc, 2i0r, 2i0s, 2i0t, 2iaa, 2iup, 2iuq, 2iur, 2iuv, 2oiz, 2ojy, 2ok4, 2ok6, 2q7q

HET: abn, bez, c2b, hy1, pea, pel, phz, pnz, pzm, tsc, tsh, tsr, tss, zhh, zhz

AAUB_ALCFA_30_390 Aralkylamine dehydrogenase heavy chain [Aromatic amine dehydrogenase heavy chain family]

volume: 138. Å3; shape: 0.64; buriedness: 1.

negative: 0.13; positive: 0.; polar: 0.14; backbone: 0.47; hydrophobic: 0.26

Multimer with: Aralkylamine dehydrogenase light chain (AAUA_ALCFA) [Aromatic amine dehydrogenase light chain family]
Domains/regions (AAUA): [R] Substrate-binding

PDB: 2agl, 2agw, 2agx, 2agy, 2agz, 2ah0, 2ah1, 2h3x, 2h47, 2hj4, 2hjb, 2hkm, 2hkr, 2hxc, 2i0r, 2i0s, 2i0t, 2iaa, 2iup, 2iuq, 2iur, 2iuv, 2oiz, 2ojy, 2ok4, 2ok6, 2q7q

HET: abn, bez, c2b, hy1, pea, pel, phz, pnz, pzm, tsc, tsh, tsr, tss, zhh, zhz

ABC3G_HUMAN_191_383 DNA dC->dU-editing enzyme APOBEC-3G [Cytidine and deoxycytidylate deaminase family]

volume: 109. Å3; shape: 0.66; buriedness: 0.62

negative: 0.; positive: 0.55; polar: 0.14; backbone: 0.; hydrophobic: 0.31

Domains/regions: [D] CMP/dCMP-type deaminase 2, [R] Necessary for homooligomerization

PDB: 3e1u, 3iqs, 3ir2, 3v4j, 3v4k, 4rov, 4row

HET: pqr

ABCBA_HUMAN_151_738 ATP-binding cassette sub-family B member 10, mitochondrial [ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily]

volume: 454. Å3; shape: 0.32; buriedness: 0.48

negative: 0.; positive: 0.27; polar: 0.38; backbone: 0.; hydrophobic: 0.35

Domains/regions: [D] ABC transmembrane type-1

PDB: 3zdq, 4ayt, 4ayw, 4ayx

HET: lmt

ABL1_HUMAN_228_509_allosteric Tyrosine-protein kinase ABL1 [Protein kinase superfamily. Tyr protein kinase family. ABL subfamily]

volume: 442. Å3; shape: 0.59; buriedness: 0.74

negative: 0.03; positive: 0.; polar: 0.07; backbone: 0.4; hydrophobic: 0.5

Domains/regions: [D] Protein kinase

PDB: 1fpu, 1iep, 1m52, 1opj, 1opk, 1opl, 2e2b, 2f4j, 2fo0, 2g1t, 2g2f, 2g2h, 2g2i, 2gqg, 2hiw, 2hyy, 2hz0, 2hz4, 2hzi, 2hzn, 2qoh, 2v7a, 2z60, 3cs9, 3dk3, 3dk6, 3dk7, 3ik3, 3k5v, 3kf4, 3kfa, 3ms9, 3mss, 3oxz, 3oy3, 3pyy, 3qri, 3qrj, 3qrk, 3ue4, 4twp, 4wa9, 4xey, 4yc8, 4zog, 5hu9, 5mo4, 6bl8

HET: 3yy, ay7, ms7, ms9, myr, stj

ABL1_HUMAN_228_509_ATPsite Tyrosine-protein kinase ABL1 [Protein kinase superfamily. Tyr protein kinase family. ABL subfamily]

volume: 781. Å3; shape: 0.35; buriedness: 0.88

negative: 0.05; positive: 0.05; polar: 0.06; backbone: 0.48; hydrophobic: 0.36

Domains/regions: [D] Protein kinase

PDB: 1fpu, 1iep, 1m52, 1opj, 1opk, 1opl, 2e2b, 2f4j, 2fo0, 2g1t, 2g2f, 2g2h, 2g2i, 2gqg, 2hiw, 2hyy, 2hz0, 2hz4, 2hzi, 2hzn, 2qoh, 2v7a, 2z60, 3cs9, 3dk3, 3dk6, 3dk7, 3ik3, 3k5v, 3kf4, 3kfa, 3ms9, 3mss, 3oxz, 3oy3, 3pyy, 3qri, 3qrj, 3qrk, 3ue4, 4twp, 4wa9, 4xey, 4yc8, 4zog, 5hu9, 5mo4, 6bl8

HET: 0li, 112, 1n1, 406, 4b7, 4st, 627, 66k, 7mp, 919, 9dp, adp, ags, axi, b90, b91, db8, gin, jin, kin, mg, nil, p16, p17, p3y, prc, pvb, sti, sx7, vx6, xy3

ABL1_HUMAN_228_509_pep Tyrosine-protein kinase ABL1 [Protein kinase superfamily. Tyr protein kinase family. ABL subfamily]

volume: 1122. Å3; shape: 0.55; buriedness: 0.46

negative: 0.; positive: 0.1; polar: 0.07; backbone: 0.47; hydrophobic: 0.35

Domains/regions: [D] Protein kinase

PDB: 1fpu, 1iep, 1m52, 1opj, 1opk, 1opl, 2e2b, 2f4j, 2fo0, 2g1t, 2g2f, 2g2h, 2g2i, 2gqg, 2hiw, 2hyy, 2hz0, 2hz4, 2hzi, 2hzn, 2qoh, 2v7a, 2z60, 3cs9, 3dk3, 3dk6, 3dk7, 3ik3, 3k5v, 3kf4, 3kfa, 3ms9, 3mss, 3oxz, 3oy3, 3pyy, 3qri, 3qrj, 3qrk, 3ue4, 4twp, 4wa9, 4xey, 4yc8, 4zog, 5hu9, 5mo4, 6bl8

HET: 66k

ABL1_HUMAN_61_120_SH3 Tyrosine-protein kinase ABL1 [Protein kinase superfamily. Tyr protein kinase family. ABL subfamily]

volume: 912. Å3; shape: 0.39; buriedness: 0.39

negative: 0.12; positive: 0.; polar: 0.42; backbone: 0.13; hydrophobic: 0.33

Domains/regions: [D] SH3

PDB: 1abo, 1abq, 1bbz, 1opk, 1opl, 2abl, 2fo0, 2o88, 3eg0, 3eg1, 3eg2, 3eg3, 3egu, 4j9b, 4j9c, 4j9d, 4j9e, 4j9f, 4j9g, 4j9h, 4j9i, 4jjb, 4jjc, 4jjd, 5mo4, 5oaz

HET: ace

ABL2_HUMAN_275_551 Abelson tyrosine-protein kinase 2 [Protein kinase superfamily. Tyr protein kinase family. ABL subfamily]

volume: 614. Å3; shape: 0.35; buriedness: 0.78

negative: 0.05; positive: 0.03; polar: 0.12; backbone: 0.49; hydrophobic: 0.31

Domains/regions: [D] Protein kinase

PDB: 2xyn, 3gvu, 3hmi, 4xli

HET: 1n1, dki, sti, vx6

ABP1_MAIZE_39_201 Auxin-binding protein 1

volume: 134. Å3; shape: 0.69; buriedness: 0.98

negative: 0.09; positive: 0.14; polar: 0.18; backbone: 0.05; hydrophobic: 0.55

Domains/regions: [R] Auxin binding

PDB: 1lr5, 1lrh

HET: nla

ACACB_HUMAN_1692_2449 Acetyl-CoA carboxylase 2

volume: 358. Å3; shape: 0.55; buriedness: 0.81

negative: 0.17; positive: 0.02; polar: 0.08; backbone: 0.43; hydrophobic: 0.3

Domains/regions: [D] CoA carboxyltransferase C-terminal, [D] CoA carboxyltransferase N-terminal, [R] Carboxyltransferase

PDB: 3ff6, 3tdc

HET: 0eu, rcp

ACACB_HUMAN_228_767 Acetyl-CoA carboxylase 2

volume: 462. Å3; shape: 0.9; buriedness: 0.82

negative: 0.05; positive: 0.13; polar: 0.09; backbone: 0.36; hydrophobic: 0.37

Domains/regions: [D] ATP-grasp, [D] Biotin carboxylation

PDB: 2hjw, 3gid, 3glk, 3jrw, 3jrx, 4hq6, 5kkn

HET: 6u3, s1a

ACAC_YEAST_1477_2229_ACoA Acetyl-CoA carboxylase

volume: 840. Å3; shape: 0.36; buriedness: 0.89

negative: 0.; positive: 0.06; polar: 0.1; backbone: 0.43; hydrophobic: 0.41

Domains/regions: [D] CoA carboxyltransferase C-terminal, [D] CoA carboxyltransferase N-terminal, [R] Acetyl-CoA binding, [R] Carboxyltransferase

PDB: 1od2, 1od4, 1uyr, 1uys, 1uyt, 1uyv, 1w2x, 3h0j, 3h0q, 3h0s, 3k8x, 3pgq, 3tv5, 3tvu, 3tvw, 3tz3, 4wyo, 4wz8, 5csk, 5csl, 5ctb, 5ctc, 5cte

HET: aco, ade, b89, coa, d1l, gy3, h1l

ACAC_YEAST_1477_2229_inhibitor Acetyl-CoA carboxylase

volume: 428. Å3; shape: 0.52; buriedness: 0.85

negative: 0.08; positive: 0.1; polar: 0.13; backbone: 0.45; hydrophobic: 0.24

Domains/regions: [D] CoA carboxyltransferase C-terminal, [D] CoA carboxyltransferase N-terminal, [R] Carboxyltransferase

PDB: 1od2, 1od4, 1uyr, 1uys, 1uyt, 1uyv, 1w2x, 3h0j, 3h0q, 3h0s, 3k8x, 3pgq, 3tv5, 3tvu, 3tvw, 3tz3, 4wyo, 4wz8, 5csk, 5csl, 5ctb, 5ctc, 5cte

HET: 07h, 3w2, 3w7, 57j, 57k, 57l, b36, b37, b38, bti, rcp

ACAC_YEAST_18_567 Acetyl-CoA carboxylase

volume: 366. Å3; shape: 0.84; buriedness: 0.77

negative: 0.07; positive: 0.17; polar: 0.15; backbone: 0.29; hydrophobic: 0.32

Domains/regions: [D] ATP-grasp, [D] Biotin carboxylation

PDB: 1w93, 1w96, 5csk, 5csl

HET: s1a

ACCC_ECOLI_1_449_catalytic Biotin carboxylase

volume: 296. Å3; shape: 0.85; buriedness: 0.79

negative: 0.16; positive: 0.24; polar: 0.16; backbone: 0.28; hydrophobic: 0.16

Domains/regions: [D] ATP-grasp, [D] Biotin carboxylation

PDB: 1bnc, 1dv1, 1dv2, 2gps, 2gpw, 2j9g, 2v58, 2v59, 2v5a, 2vr1, 2w6m, 2w6n, 2w6o, 2w6p, 2w6q, 2w6z, 2w70, 2w71, 3g8c, 3g8d, 3jzf, 3jzi, 3rup, 3rv3, 3rv4, 4hr7

HET: adp, btn

ACCC_HAEIN_2_448 Biotin carboxylase

volume: 159. Å3; shape: 0.39; buriedness: 0.79

negative: 0.15; positive: 0.28; polar: 0.27; backbone: 0.15; hydrophobic: 0.15

Domains/regions: [D] ATP-grasp, [D] Biotin carboxylation

PDB: 4mv1, 4mv3, 4mv4, 4mv6, 4mv7, 4mv8, 4mv9, 4rzq

HET: pct, ppf, y7y

ACCD_STAA8_1_285 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta [AccD/PCCB family]

volume: 361. Å3; shape: 0.68; buriedness: 0.78

negative: 0.; positive: 0.; polar: 0.12; backbone: 0.56; hydrophobic: 0.32

Multimer with: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCA_STAA8) [AccA family]
Domains/regions (ACCD): [D] CoA carboxyltransferase N-terminal
Domains/regions (ACCA): [D] CoA carboxyltransferase C-terminal

PDB: 2f9i, 5kdr

HET: yt5

ACE2_HUMAN_18_615 Angiotensin-converting enzyme 2 [Peptidase M2 family]

volume: 311. Å3; shape: 0.57; buriedness: 0.78

negative: 0.39; positive: 0.27; polar: 0.33; backbone: 0.; hydrophobic: 0.

PDB: 1r42, 1r4l, 2ajf, 3d0g, 3d0h, 3d0i, 3kbh, 3sci, 3scj, 3sck, 3scl

HET: xx5, zn

ACE_DROME_16_614 Angiotensin-converting enzyme [Peptidase M2 family]

volume: 591. Å3; shape: 0.51; buriedness: 0.78

negative: 0.13; positive: 0.26; polar: 0.26; backbone: 0.13; hydrophobic: 0.22

PDB: 1j36, 1j37, 1j38, 2x8y, 2x8z, 2x90, 2x91, 2x92, 2x93, 2x94, 2x95, 2x96, 2x97, 2xhm, 3zqz, 4aa1, 4aa2, 4asq, 4asr, 4ca7, 4ca8, 5a2r

HET: 3ef, 3es, eal, k26, lpr, mlt, rx3, rx4, slc, x8z, x92, x93, x94, x95

ACE_HUMAN_30_650 Angiotensin-converting enzyme [Peptidase M2 family]

volume: 621. Å3; shape: 0.52; buriedness: 0.78

negative: 0.13; positive: 0.26; polar: 0.3; backbone: 0.13; hydrophobic: 0.17

Domains/regions: [R] Peptidase M2 1

PDB: 2c6f, 2c6n, 2xyd, 3nxq, 4bxk, 4bzs, 4ca6, 4ufa, 4ufb, 5am8, 5am9, 5ama, 5amb, 5amc, 6en5, 6en6, 6f9r, 6f9v

HET: 1iu, 3ef, 3es, 9x6, bj2, d0w, d0z, k26, lpr, niy, p6g, rx4, sac

ACE_HUMAN_650_1231 Angiotensin-converting enzyme [Peptidase M2 family]

volume: 849. Å3; shape: 0.4; buriedness: 0.79

negative: 0.12; positive: 0.23; polar: 0.19; backbone: 0.14; hydrophobic: 0.32

Domains/regions: [R] Peptidase M2 2

PDB: 1o86, 1o8a, 1uze, 1uzf, 2iul, 2iux, 2oc2, 2xy9, 2ydm, 3bkk, 3bkl, 3l3n, 4aph, 4apj, 4bzr, 4c2n, 4c2o, 4c2p, 4c2q, 4c2r, 4ca5, 6f9t, 6f9u

HET: 3ef, 3es, d0w, d0z, eal, k26, kaf, kaw, lpr, lsw, mco, nxa, pca, rx3, slc, x8z

ACES_ANOGA_162_709 Acetylcholinesterase [Type-B carboxylesterase/lipase family]

volume: 140. Å3; shape: 0.59; buriedness: 0.91

negative: 0.07; positive: 0.07; polar: 0.13; backbone: 0.42; hydrophobic: 0.31

PDB: 5x61, 5ydh, 5ydi, 5ydj, 6arx, 6ary

HET: bt7, na

ACES_DROME_39_623 Acetylcholinesterase [Type-B carboxylesterase/lipase family]

volume: 207. Å3; shape: 0.82; buriedness: 0.94

negative: 0.11; positive: 0.04; polar: 0.29; backbone: 0.25; hydrophobic: 0.32

PDB: 1dx4, 1qo9, 1qon

HET: 760, i40

ACES_HUMAN_33_574 Acetylcholinesterase [Type-B carboxylesterase/lipase family]

volume: 753. Å3; shape: 0.48; buriedness: 0.91

negative: 0.08; positive: 0.04; polar: 0.25; backbone: 0.36; hydrophobic: 0.28

Domains/regions: [R] Galanthamine binding

PDB: 1b41, 1f8u, 2x8b, 3lii, 4bdt, 4ey4, 4ey5, 4ey6, 4ey7, 4ey8, 4m0e, 4m0f, 4pqe, 5fpq, 5hf5, 5hf6, 5hf8, 5hf9, 5hfa, 5hq3

HET: 1yk, 1yl, dep, e20, efs, fp1, gnt, hi6, hup, huw, vx

ACES_MOUSE_32_575 Acetylcholinesterase [Type-B carboxylesterase/lipase family]

volume: 979. Å3; shape: 0.48; buriedness: 0.85

negative: 0.07; positive: 0.06; polar: 0.24; backbone: 0.42; hydrophobic: 0.21

PDB: 1j06, 1j07, 1ku6, 1maa, 1mah, 1n5m, 1n5r, 1q83, 1q84, 2c0p, 2c0q, 2gyu, 2gyv, 2gyw, 2h9y, 2ha0, 2ha2, 2ha3, 2ha4, 2ha5, 2ha6, 2ha7, 2jey, 2jez, 2jf0, 2jge, 2jgf, 2jgi, 2jgj, 2jgk, 2jgl, 2jgm, 2whp, 2whq, 2whr, 2wls, 2wu3, 2wu4, 2xud, 2xuf, 2xug, 2xuh, 2xui, 2xuj, 2xuk, 2xuo, 2xup, 2xuq, 2y2u, 2y2v, 3dl4, 3dl7, 3zlt, 3zlu, 3zlv, 4a16, 4a23, 4ara, 4arb, 4b7z, 4b80, 4b81, 4b82, 4b83, 4b84, 4b85, 4bc0, 4bc1, 4btl, 5dti, 5dtj, 5ehn, 5ehq, 5ehz, 5eia, 5eie, 5eih, 5fkj, 5foq, 5fpp, 5fum, 5hcu, 5ov9

HET: 1ka, 4oj, 5g8, 5gz, 5nz, 5o2, a36, ach, ae3, at3, atj, b3v, b3w, b3z, bch, bua, c56, c57, chh, cht, cvi, dcu, dme, etm, g0w, gc8, gmn, h34, hbp, hi6, hlo, k27, me2, naf, ntj, nwa, obi, pe3, pg0, pg4, pge, prm, pz5, q4q, sck, scu, sof, tqv, tz2, tz4, tz5, x13, z5k, zn4

ACES_TETCF_21_559 Acetylcholinesterase [Type-B carboxylesterase/lipase family]

volume: 800. Å3; shape: 0.5; buriedness: 0.82

negative: 0.07; positive: 0.04; polar: 0.22; backbone: 0.31; hydrophobic: 0.36

PDB: 1acj, 1acl, 1amn, 1ax9, 1cfj, 1dx6, 1e3q, 1e66, 1ea5, 1eve, 1fss, 1gpk, 1gpn, 1gqr, 1gqs, 1h22, 1h23, 1hbj, 1jjb, 1oce, 1odc, 1qid, 1qie, 1qif, 1qig, 1qih, 1qii, 1qij, 1qik, 1qim, 1qti, 1som, 1u65, 1ut6, 1vot, 1vxo, 1vxr, 1w4l, 1w6r, 1w75, 1w76, 1zgb, 1zgc, 2ace, 2ack, 2bag, 2c4h, 2c58, 2c5f, 2c5g, 2cek, 2ckm, 2cmf, 2dfp, 2j3d, 2j3q, 2j4f, 2v96, 2v97, 2v98, 2va9, 2vja, 2vjb, 2vjc, 2vjd, 2vq6, 2vt6, 2vt7, 2w6c, 2wfz, 2wg0, 2wg1, 2wg2, 2xi4, 3gel, 3i6m, 3i6z, 3m3d, 3zv7, 4tvk, 4w63, 4x3c, 5bwb, 5bwc, 5dlp, 5e2i, 5e4j, 5e4t, 5ehx, 5ei5, 5ih7, 6fot, 6fou, 6fov

HET: 03s, 1pe, 4vv, a1e, a2e, a8b, a8n, aa7, ae4, aft, at3, bm4, ccd, chh, cp0, dme, e0z, e10, e12, e1k, e1n, e20, ebw, edr, emm, etm, f11, fbq, fp1, g3x, g6x, gb, gd8, gl8, gnt, gsg, hbp, htb, hub, hup, hux, mbt, mf2, n8t, naf, nhg, nwa, omi, pe7, pg4, pge, saf, tfl, tha, tjh, tnh, vx

ACFR2_ARATH_1_230 Probable transmembrane ascorbate ferrireductase 2

volume: 100. Å3; shape: 0.69; buriedness: 0.64

negative: 0.; positive: 0.33; polar: 0.22; backbone: 0.22; hydrophobic: 0.22

Domains/regions: [D] Cytochrome b561

PDB: 4o6y, 4o79, 4o7g

HET: asc

ACHA2_HUMAN_59_265 Neuronal acetylcholine receptor subunit alpha-2 [Ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha- 2/CHRNA2 sub-subfamily]

volume: 127. Å3; shape: 0.52; buriedness: 0.99

negative: 0.; positive: 0.; polar: 0.36; backbone: 0.31; hydrophobic: 0.33

PDB: 5fjv

HET: epj

ACHA9_HUMAN_26_237 Neuronal acetylcholine receptor subunit alpha-9 [Ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha- 9/CHRNA9 sub-subfamily]

volume: 504. Å3; shape: 0.73; buriedness: 0.43

negative: 0.; positive: 0.; polar: 0.3; backbone: 0.42; hydrophobic: 0.27

PDB: 4d01, 4uxu, 4uy2

HET: mlk

ACHP_LYMST_17_229 Acetylcholine-binding protein

volume: 519. Å3; shape: 0.67; buriedness: 0.95

negative: 0.; positive: 0.05; polar: 0.28; backbone: 0.43; hydrophobic: 0.25

Domains/regions: [D] Ig-like

PDB: 1i9b, 1uv6, 1uw6, 1ux2, 2zju, 2zjv, 3u8j, 3u8k, 3u8l, 3u8m, 3u8n, 3wip, 3wth, 3wti, 3wtj, 3wtk, 3wtl, 3wtm, 3wtn, 3wto, 3zdg, 3zdh, 4alx, 4nzb, 4qaa, 4qab, 4qac, 4um1, 4zjt, 4zk1, 4zr6, 4zru, 5bp0, 5j5f, 5j5g, 5j5h, 5j5i, 5t90

HET: 09o, 09p, 09q, 09r, 09s, 1pe, 4p6, 4p7, 4qw, 6gf, 6gh, 6gk, 6gm, ach, cce, ct4, fn1, im4, izn, kk1, kk2, kk3, mg, n1y, n2y, nct, nse, th4, ti9, xrs, xrx

ACK1_HUMAN_113_392 Activated CDC42 kinase 1 [Protein kinase superfamily. Tyr protein kinase family]

volume: 624. Å3; shape: 0.58; buriedness: 0.74

negative: 0.07; positive: 0.04; polar: 0.07; backbone: 0.44; hydrophobic: 0.37

Domains/regions: [D] Protein kinase

PDB: 1u46, 1u4d, 1u54, 3eqp, 3eqr, 4ewh, 4hzr, 4hzs, 4id7

HET: 1g0, acp, dbq, mg, t74, t77, t95

ACM1_HUMAN_1_460 Muscarinic acetylcholine receptor M1 [G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM1 sub-subfamily]

volume: 217. Å3; shape: 0.7; buriedness: 0.99

negative: 0.07; positive: 0.; polar: 0.53; backbone: 0.13; hydrophobic: 0.27

PDB: 5cxv

HET: 0hk

ACM2_HUMAN_1_466_alloECL Muscarinic acetylcholine receptor M2 [G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily]

volume: 274. Å3; shape: 0.6; buriedness: 0.73

negative: 0.06; positive: 0.; polar: 0.66; backbone: 0.09; hydrophobic: 0.19

Domains/regions: [R] Agonist binding

PDB: 3uon, 4mqs, 4mqt

HET: 2cu

ACM2_HUMAN_1_466_Galpha Muscarinic acetylcholine receptor M2 [G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily]

volume: 629. Å3; shape: 0.94; buriedness: 0.48

negative: 0.; positive: 0.21; polar: 0.36; backbone: 0.18; hydrophobic: 0.24

PDB: 3uon, 4mqs, 4mqt

ACM2_HUMAN_1_466_TM Muscarinic acetylcholine receptor M2 [G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily]

volume: 221. Å3; shape: 0.78; buriedness: 1.

negative: 0.06; positive: 0.; polar: 0.35; backbone: 0.2; hydrophobic: 0.39

Domains/regions: [R] Agonist binding

PDB: 3uon, 4mqs, 4mqt

HET: ixo, qnb

ACM3_HUMAN_57_579 Muscarinic acetylcholine receptor M3 [G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily]

volume: 216. Å3; shape: 0.71; buriedness: 0.99

negative: 0.09; positive: 0.; polar: 0.55; backbone: 0.; hydrophobic: 0.36

Domains/regions: [R] Agonist binding

PDB: 4daj, 4u14, 4u15, 4u16

HET: 0hk, 3c0

ACM4_HUMAN_20_479 Muscarinic acetylcholine receptor M4 [G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM4 sub-subfamily]

volume: 216. Å3; shape: 0.7; buriedness: 0.99

negative: 0.; positive: 0.; polar: 0.48; backbone: 0.16; hydrophobic: 0.35

PDB: 5dsg

HET: 0hk

ACMSD_HUMAN_1_333 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase [Metallo-dependent hydrolases superfamily. ACMSD family]

volume: 121. Å3; shape: 0.65; buriedness: 0.95

negative: 0.1; positive: 0.27; polar: 0.; backbone: 0.09; hydrophobic: 0.54

PDB: 2wm1, 4igm, 4ign, 4ih3, 4ofc

HET: 13p, pdc

ACON_BOVIN_28_780 Aconitate hydratase, mitochondrial [Aconitase/IPM isomerase family]

volume: 118. Å3; shape: 0.82; buriedness: 0.96

negative: 0.06; positive: 0.28; polar: 0.29; backbone: 0.24; hydrophobic: 0.13

Domains/regions: [R] Substrate binding

PDB: 1aco, 1ami, 1amj, 1b0j, 1b0k, 1b0m, 1c96, 1c97, 1fgh, 1nis, 1nit, 5acn, 6acn, 7acn, 8acn

HET: ath, ict, mic, nic, ntc, tra

ACOX_SYNY3_1_490 Apocarotenoid-15,15'-oxygenase [Carotenoid oxygenase family]

volume: 476. Å3; shape: 0.37; buriedness: 0.8

negative: 0.14; positive: 0.15; polar: 0.15; backbone: 0.07; hydrophobic: 0.49

PDB: 2biw, 2bix, 4ou8, 4ou9, 5kja, 5kjb, 5kjd, 5kk0

HET: 3on, c8e

ACP1_SPIOL_57_138 Acyl carrier protein 1, chloroplastic [Acyl carrier protein (ACP) family]

volume: 77. Å3; shape: 0.77; buriedness: 0.38

negative: 0.; positive: 0.; polar: 0.; backbone: 0.5; hydrophobic: 0.5

PDB: 2xz0, 2xz1

HET: pny

ACP_ECOLI_1_78 Acyl carrier protein [Acyl carrier protein (ACP) family]

volume: 3100. Å3; shape: 0.91; buriedness: 0.19

negative: 0.17; positive: 0.; polar: 0.16; backbone: 0.39; hydrophobic: 0.28

Domains/regions: [D] Carrier

PDB: 1l0h, 1l0i, 1t8k, 2fac, 2fad, 2fae, 2fhs, 3ejb, 3ejd, 3eje, 3ny7, 4etw, 4ihf, 4ihg, 4ihh, 4keh, 5kof, 5usr, 5wgb, 5wkp, 5wlw

HET: 1f7, 1r3, 6w5, 8q1, htg, pm4, pm5, pm8, pns, pse, psr, sxm, zmk, zmo, zmp, zmq, zn

ACPS_MYCTU_1_130 Holo-[acyl-carrier-protein] synthase [P-Pant transferase superfamily. AcpS family]

volume: 104. Å3; shape: 0.81; buriedness: 0.6

negative: 0.22; positive: 0.24; polar: 0.14; backbone: 0.39; hydrophobic: 0.

PDB: 3h7q, 3hqj, 3ne1, 3ne3, 4hc6

HET: bcn

ACRB_ECOLI_1_1048_ampicillin Multidrug efflux pump subunit AcrB [Resistance-nodulation-cell division (RND) (TC 2.A.6) family]

volume: 2456. Å3; shape: 0.69; buriedness: 0.39

negative: 0.; positive: 0.05; polar: 0.11; backbone: 0.48; hydrophobic: 0.36

PDB: 1iwg, 1oye, 1t9t, 1t9u, 1t9w, 1t9x, 2dhh, 2dr6, 2drd, 2gif, 2hqf, 2hqg, 2i6w, 2j8s, 2rdd, 3aoa, 3aob, 3aoc, 3aod, 3d9b, 3noc, 3nog, 3w9h, 4c48, 4dx5, 4dx6, 4dx7, 4k7q, 4u8v, 4u8y, 4u95, 4u96, 4zlj, 4zll, 5en5, 5eno, 5enp, 5enq, 5enr, 5ens, 5ent, 5jmn, 5nc5, 5yil

HET: aic, cpf, d10, d12, dd9, et, ete, lmt, nfn, oct, pty, zld

ACRB_ECOLI_1_1048_doxorubicin Multidrug efflux pump subunit AcrB [Resistance-nodulation-cell division (RND) (TC 2.A.6) family]

volume: 1976. Å3; shape: 0.53; buriedness: 0.7

negative: 0.01; positive: 0.05; polar: 0.17; backbone: 0.38; hydrophobic: 0.38

PDB: 1iwg, 1oye, 1t9t, 1t9u, 1t9w, 1t9x, 2dhh, 2dr6, 2drd, 2gif, 2hqf, 2hqg, 2i6w, 2j8s, 2rdd, 3aoa, 3aob, 3aoc, 3aod, 3d9b, 3noc, 3nog, 3w9h, 4c48, 4dx5, 4dx6, 4dx7, 4k7q, 4u8v, 4u8y, 4u95, 4u96, 4zlj, 4zll, 5en5, 5eno, 5enp, 5enq, 5enr, 5ens, 5ent, 5jmn, 5nc5, 5yil

HET: 5qe, 5qf, 5qg, cpf, dm2, ery, et, lmu, mbx, miy, nfn, p9d, puy, rfp, rhq

ACRB_ECOLI_1_39 Multidrug efflux pump subunit AcrB [Resistance-nodulation-cell division (RND) (TC 2.A.6) family]

volume: 1030. Å3; shape: 0.57; buriedness: 0.46

negative: 0.; positive: 0.; polar: 0.18; backbone: 0.12; hydrophobic: 0.7

PDB: 1iwg, 1oye, 1t9t, 1t9u, 1t9w, 1t9x, 2dhh, 2dr6, 2drd, 2gif, 2hqf, 2hqg, 2i6w, 2j8s, 2rdd, 3aoa, 3aob, 3aoc, 3aod, 3d9b, 3noc, 3nog, 3w9h, 4c48, 4dx5, 4dx6, 4dx7, 4k7q, 4u8v, 4u8y, 4u95, 4u96, 4zlj, 4zll, 5jmn, 5nc5, 5yil

HET: c14, d10, d12, hex, oct, pty

ACS2A_HUMAN_30_577 Acyl-coenzyme A synthetase ACSM2A, mitochondrial [ATP-dependent AMP-binding enzyme family]

volume: 475. Å3; shape: 0.81; buriedness: 0.9

negative: 0.07; positive: 0.06; polar: 0.26; backbone: 0.44; hydrophobic: 0.16

PDB: 2vze, 2wd9, 3b7w, 3c5e, 3day, 3eq6, 3gpc

HET: amp, apc, atp, coa, ibp, mg, unl

ACSE_MOOTH_1_262 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase [Vitamin-B12 dependent methionine synthase family]

volume: 369. Å3; shape: 0.35; buriedness: 0.71

negative: 0.2; positive: 0.07; polar: 0.25; backbone: 0.14; hydrophobic: 0.34

Domains/regions: [D] Pterin-binding, [R] Cobalamin binding

PDB: 1f6y, 2e7f, 2ogy, 4djd, 4djf

HET: c2f

ACT3_STRCO_2_261 Putative ketoacyl reductase [Short-chain dehydrogenases/reductases (SDR) family]

volume: 345. Å3; shape: 0.78; buriedness: 0.78

negative: 0.; positive: 0.; polar: 0.34; backbone: 0.27; hydrophobic: 0.4

PDB: 1w4z, 1x7g, 1x7h, 1xr3, 2rh4, 2rhc, 2rhr, 3csd, 3qrw, 3ri3, 4dbz, 4dc0, 4dc1

HET: emo, isz

ACTB_HUMAN_1_375_ATPsite Actin, cytoplasmic 1 [Actin family]

volume: 342. Å3; shape: 0.42; buriedness: 0.88

negative: 0.09; positive: 0.15; polar: 0.12; backbone: 0.55; hydrophobic: 0.1

PDB: 1atn, 1c0f, 1c0g, 1d4x, 1dej, 1eqy, 1esv, 1h1v, 1hlu, 1ijj, 1j6z, 1kxp, 1lcu, 1lot, 1ma9, 1mdu, 1nlv, 1nm1, 1nmd, 1nwk, 1p8z, 1qz5, 1qz6, 1rdw, 1rfq, 1rgi, 1s22, 1sqk, 1t44, 1wua, 1y64, 1yxq, 2a3z, 2a40, 2a41, 2a42, 2a5x, 2asm, 2aso, 2asp, 2btf, 2d1k, 2ff3, 2ff6, 2fxu, 2gwj, 2gwk, 2hf3, 2hf4, 2hmp, 2oan, 2pav, 2pbd, 2q0r, 2q0u, 2q1n, 2q31, 2q36, 2q97, 2v51, 2v52, 2vcp, 2vyp, 2yje, 2yjf, 2zwh, 3a5l, 3a5m, 3a5n, 3a5o, 3buz, 3chw, 3ci5, 3cip, 3cjb, 3daw, 3eks, 3eku, 3el2, 3ffk, 3hbt, 3m1f, 3m6g, 3mmv, 3mn5, 3mn6, 3mn7, 3mn9, 3sjh, 3tpq, 3tu5, 3u4l, 3u8x, 3u9d, 3u9z, 3ub5, 3ue5, 3w3d, 4b1u, 4b1v, 4b1w, 4b1x, 4b1y, 4b1z, 4ci6, 4eah, 4efh, 4gy2, 4h03, 4h0t, 4h0v, 4h0x, 4h0y, 4jhd, 4k41, 4k42, 4k43, 4m63, 4pkg, 4pkh, 4pki, 4pl8, 4rwt, 4z94, 5ce3, 5ubo, 5wfn, 6c1d

HET: adp, anp, atp, ca

ACTB_HUMAN_1_375_CY9 Actin, cytoplasmic 1 [Actin family]

volume: 3168. Å3; shape: 0.48; buriedness: 0.37

negative: 0.05; positive: 0.; polar: 0.25; backbone: 0.47; hydrophobic: 0.23

PDB: 1atn, 1c0f, 1c0g, 1d4x, 1dej, 1eqy, 1esv, 1h1v, 1hlu, 1ijj, 1j6z, 1kxp, 1lcu, 1lot, 1ma9, 1mdu, 1nlv, 1nm1, 1nmd, 1nwk, 1p8z, 1qz5, 1qz6, 1rdw, 1rfq, 1rgi, 1s22, 1sqk, 1t44, 1wua, 1y64, 1yxq, 2a3z, 2a40, 2a41, 2a42, 2a5x, 2asm, 2aso, 2asp, 2btf, 2d1k, 2ff3, 2ff6, 2fxu, 2gwj, 2gwk, 2hf3, 2hf4, 2hmp, 2oan, 2pav, 2pbd, 2q0r, 2q0u, 2q1n, 2q31, 2q36, 2q97, 2v51, 2v52, 2vcp, 2vyp, 2yje, 2yjf, 2zwh, 3a5l, 3a5m, 3a5n, 3a5o, 3buz, 3chw, 3ci5, 3cip, 3cjb, 3daw, 3eks, 3eku, 3el2, 3ffk, 3hbt, 3m1f, 3m6g, 3mmv, 3mn5, 3mn6, 3mn7, 3mn9, 3sjh, 3tpq, 3tu5, 3u4l, 3u8x, 3u9d, 3u9z, 3ub5, 3ue5, 3w3d, 4b1u, 4b1v, 4b1w, 4b1x, 4b1y, 4b1z, 4ci6, 4eah, 4efh, 4gy2, 4h03, 4h0t, 4h0v, 4h0x, 4h0y, 4jhd, 4k41, 4k42, 4k43, 4m63, 4pkg, 4pkh, 4pki, 4pl8, 4rwt, 4z94, 5ce3, 5ubo, 5wfn, 6c1d

HET: 1pe, 1po, 211, ap8, bid, cy9, jas, kab, lo3, nwm, p6g, rga, rgc, rho, spd, spx, swi, ula

ACTN_ACTCH_127_345 Actinidain [Peptidase C1 family]

volume: 309. Å3; shape: 0.65; buriedness: 0.72

negative: 0.03; positive: 0.11; polar: 0.17; backbone: 0.53; hydrophobic: 0.17

PDB: 1aec, 2act

HET: e64

entries 1–100 [>>]