[POCKETOME]
 

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BPHD_BURXL_2_286 [text] 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase [AB hydrolase superfamily. BphD family]

volume: 270. Å3; shape: 0.34; buriedness: 0.96

negative: 0.; positive: 0.06; polar: 0.1; backbone: 0.33; hydrophobic: 0.51

Domains/regions: [R] Substrate binding

PDB: 2og1, 2pu5, 2pu7, 2puh, 2puj, 2rht, 2rhw, 2ri6, 3v1k, 3v1l, 3v1m, 3v1n

HET: bez, c0e, c1e, hpk, hpz, mla, mli

BPHL_HUMAN_38_291 [text] Valacyclovir hydrolase [AB hydrolase superfamily. Lipase family]

volume: 119. Å3; shape: 0.5; buriedness: 0.92

negative: 0.05; positive: 0.05; polar: 0.13; backbone: 0.37; hydrophobic: 0.4

Domains/regions: [D] AB hydrolase-1

PDB: 2ocg, 2oci, 2ock, 2ocl

HET: tyc

D14_ORYSJ_50_318 [text] Strigolactone esterase D14 [AB hydrolase superfamily]

volume: 216. Å3; shape: 0.42; buriedness: 0.96

negative: 0.; positive: 0.07; polar: 0.22; backbone: 0.22; hydrophobic: 0.48

PDB: 3vxk, 3w04, 3w05, 3wio, 4ih9, 4iha, 5dj5

HET: gr2, h3m, opl, pms

EPHB_MYCTO_1_356 [text] Epoxide hydrolase B [AB hydrolase superfamily. Epoxide hydrolase family]

volume: 106. Å3; shape: 0.37; buriedness: 0.99

negative: 0.13; positive: 0.13; polar: 0.33; backbone: 0.; hydrophobic: 0.4

Domains/regions: [D] AB hydrolase-1

PDB: 2e3j, 2zjf

HET: bsu

EST2_PSEFL_1_218 [text] Carboxylesterase 2 [AB hydrolase superfamily. AB hydrolase 2 family]

volume: 119. Å3; shape: 0.72; buriedness: 0.81

negative: 0.; positive: 0.1; polar: 0.2; backbone: 0.27; hydrophobic: 0.44

PDB: 1auo, 1aur

HET: pms

ESTA_BACSU_33_212 [text] Lipase EstA [AB hydrolase superfamily]

volume: 366. Å3; shape: 0.28; buriedness: 0.72

negative: 0.; positive: 0.1; polar: 0.1; backbone: 0.34; hydrophobic: 0.45

PDB: 1i6w, 1isp, 1r4z, 1r50, 1t2n, 1t4m, 2qxt, 2qxu, 3d2a, 3d2b, 3d2c, 3qmm, 3qzu, 5cri, 5ct4, 5ct5, 5ct6, 5ct8, 5ct9, 5cta, 5cur

HET: bm0, ril, sil

FAEA_ASPNG_22_281 [text] Feruloyl esterase A [AB hydrolase superfamily. FaeA family]

volume: 171. Å3; shape: 0.55; buriedness: 0.88

negative: 0.08; positive: 0.08; polar: 0.32; backbone: 0.21; hydrophobic: 0.3

PDB: 1usw, 1uwc, 1uza, 2bjh, 2hl6, 2ix9

HET: fer

HNL_HEVBR_1_257 [text] (S)-hydroxynitrile lyase [AB hydrolase superfamily. Hydroxynitrile lyase family]

volume: 103. Å3; shape: 0.79; buriedness: 1.

negative: 0.; positive: 0.21; polar: 0.16; backbone: 0.08; hydrophobic: 0.54

Domains/regions: [D] AB hydrolase-1

PDB: 1qj4, 1sc9, 1sci, 1sck, 1scq, 1yas, 1yb6, 1yb7, 2g4l, 2yas, 3c6x, 3c6y, 3c6z, 3c70, 3yas, 4yas, 5yas, 6yas, 7yas

HET: clx, cnh, fac, icn, mnn

HOD_ARTNT_1_276 [text] 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase [AB hydrolase superfamily]

volume: 123. Å3; shape: 0.78; buriedness: 0.99

negative: 0.; positive: 0.27; polar: 0.15; backbone: 0.08; hydrophobic: 0.5

Domains/regions: [D] AB hydrolase-1, [R] Substrate binding

PDB: 2wj3, 2wj4, 2wj6, 2wm2, 4cfs

HET: hqd, zz8

HSAD_MYCTU_1_291 [text] 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase [AB hydrolase superfamily. HsaD family]

volume: 236. Å3; shape: 0.36; buriedness: 0.9

negative: 0.; positive: 0.07; polar: 0.07; backbone: 0.27; hydrophobic: 0.59

Domains/regions: [R] Substrate binding

PDB: 2vf2, 2wud, 2wue, 2wuf, 2wug

HET: hpk, kek, kem

HYES_HUMAN_1_230 [text] Bifunctional epoxide hydrolase 2 [AB hydrolase superfamily. Epoxide hydrolase family]

volume: 302. Å3; shape: 0.58; buriedness: 0.76

negative: 0.16; positive: 0.; polar: 0.28; backbone: 0.2; hydrophobic: 0.37

Domains/regions: [R] Phosphatase

PDB: 1s8o, 1vj5, 1zd2, 1zd3, 1zd4, 1zd5, 3i1y, 3i28, 3koo, 3otq, 3wk4, 3wk5, 3wk6, 3wk7, 3wk8, 3wk9, 3wka, 3wkb, 3wkc, 3wkd, 3wke, 4hai, 4j03, 4ocz, 4od0, 4y2j, 4y2p, 4y2q, 4y2r, 4y2s, 4y2t, 4y2u, 4y2v, 4y2x, 4y2y, 5ahx, 5ai0, 5ai4, 5ai5, 5ai6, 5ai8, 5ai9, 5aia, 5aib, 5aic, 5ak3, 5ak4, 5ak5, 5ak6, 5ake, 5akg, 5akh, 5aki, 5akj, 5akk, 5akl, 5akx, 5aky, 5akz, 5ald, 5ale, 5alf, 5alg, 5alh, 5ali, 5alj, 5alk, 5all, 5alm, 5aln, 5alo, 5alp, 5alq, 5alr, 5als, 5alt, 5alu, 5alv, 5alw, 5alx, 5aly, 5alz, 5am0, 5am1, 5am2, 5am3, 5am4, 5am5, 5fp0

HET: hd2

HYES_HUMAN_230_551 [text] Bifunctional epoxide hydrolase 2 [AB hydrolase superfamily. Epoxide hydrolase family]

volume: 675. Å3; shape: 0.45; buriedness: 0.91

negative: 0.08; positive: 0.04; polar: 0.15; backbone: 0.19; hydrophobic: 0.54

Domains/regions: [D] AB hydrolase-1, [R] Epoxide hydrolase

PDB: 1s8o, 1vj5, 1zd2, 1zd3, 1zd4, 1zd5, 3ans, 3ant, 3i1y, 3i28, 3koo, 3otq, 3pdc, 3wk4, 3wk5, 3wk6, 3wk7, 3wk8, 3wk9, 3wka, 3wkb, 3wkc, 3wkd, 3wke, 4c4x, 4c4y, 4c4z, 4hai, 4j03, 4jnc, 4ocz, 4od0, 4x6x, 4x6y, 4y2j, 4y2p, 4y2q, 4y2r, 4y2s, 4y2t, 4y2u, 4y2v, 4y2x, 4y2y, 5ahx, 5ai0, 5ai4, 5ai5, 5ai6, 5ai8, 5ai9, 5aia, 5aib, 5aic, 5ak3, 5ak4, 5ak5, 5ak6, 5ake, 5akg, 5akh, 5aki, 5akj, 5akk, 5akl, 5akx, 5aky, 5akz, 5ald, 5ale, 5alf, 5alg, 5alh, 5ali, 5alj, 5alk, 5all, 5alm, 5aln, 5alo, 5alp, 5alq, 5alr, 5als, 5alt, 5alu, 5alv, 5alw, 5alx, 5aly, 5alz, 5am0, 5am1, 5am2, 5am3, 5am4, 5am5, 5fp0

HET: 1lf, 24d, 2ru, 2rv, 33n, 34n, 3c5, 49g, 49n, 49o, 49p, 49q, 49r, 49z, 4a0, 4a5, 4ua, 4vy, 5dq, 5zm, 6n0, 6n4, 6n8, 6nf, 6nj, 6nm, 6nz, 7gm, 7wi, 8tm, 9xz, a0j, aub, b7h, bsu, ciu, dul, fcw, fvs, gzp, hd2, i23, i5t, jqn, k78, kwb, lws, mvj, mzl, nc3, nc4, nc6, nc7, oe1, onr, q3b, qyd, r4n, s0a, s0b, s0c, s0d, s0e, s0f, s0g, s0i, s0j, s0k, s38, s74, s82, s94, szc, t5j, v2z, w9l, w9m, wmr, xq9, zyi

HYES_MOUSE_1_554 [text] Bifunctional epoxide hydrolase 2 [AB hydrolase superfamily. Epoxide hydrolase family]

volume: 324. Å3; shape: 0.34; buriedness: 0.89

negative: 0.07; positive: 0.07; polar: 0.2; backbone: 0.14; hydrophobic: 0.53

Domains/regions: [D] AB hydrolase-1, [R] Epoxide hydrolase

PDB: 1cqz, 1cr6, 1ek1, 1ek2

HET: cdu, ciu, cpu

KAI2_ARATH_1_270 [text] Probable esterase KAI2 [AB hydrolase superfamily]

volume: 135. Å3; shape: 0.83; buriedness: 0.97

negative: 0.; positive: 0.11; polar: 0.22; backbone: 0.; hydrophobic: 0.67

PDB: 3w06, 4hrx, 4hry, 4hta, 4ih1, 4jym, 4jyp

HET: kkn, tam

LIP_BURCE_45_364 [text] Lipase [AB hydrolase superfamily. Pseudomonas lipase family]

volume: 506. Å3; shape: 0.87; buriedness: 0.84

negative: 0.; positive: 0.08; polar: 0.28; backbone: 0.26; hydrophobic: 0.38

Domains/regions: [D] AB hydrolase-1

PDB: 1hqd, 1oil, 1ys1, 1ys2, 2lip, 2nw6, 3lip, 4lip, 5lip

HET: 2hr, 2hs, ccp, ink, ocp, pot

LIPP_HUMAN_17_465 [text] Pancreatic triacylglycerol lipase [AB hydrolase superfamily. Lipase family]

volume: 556. Å3; shape: 0.58; buriedness: 0.67

negative: 0.03; positive: 0.1; polar: 0.09; backbone: 0.38; hydrophobic: 0.4

PDB: 1lpa, 1lpb, 1n8s

HET: mup, plc

LIP_THELA_23_291 [text] Lipase [AB hydrolase superfamily. Lipase family]

volume: 383. Å3; shape: 0.69; buriedness: 0.65

negative: 0.; positive: 0.12; polar: 0.2; backbone: 0.53; hydrophobic: 0.15

PDB: 1dt3, 1dt5, 1dte, 1du4, 1ein, 1gt6, 1tib, 4dyh, 4ea6, 4flf, 4gbg, 4ghw, 4gi1, 4glb, 4gwl, 4kjx, 4n8s, 4s0x, 4zgb, 5ap9

HET: 16y, dao, dka, eac, xxh

LYPA1_HUMAN_3_230 [text] Acyl-protein thioesterase 1 [AB hydrolase superfamily. AB hydrolase 2 family]

volume: 285. Å3; shape: 0.43; buriedness: 0.96

negative: 0.03; positive: 0.04; polar: 0.08; backbone: 0.45; hydrophobic: 0.41

PDB: 1fj2, 5sym

HET: 71q

LYPL1_HUMAN_1_237 [text] Lysophospholipase-like protein 1 [AB hydrolase superfamily. AB hydrolase 2 family]

volume: 114. Å3; shape: 0.7; buriedness: 0.82

negative: 0.; positive: 0.09; polar: 0.27; backbone: 0.27; hydrophobic: 0.36

PDB: 3u0v, 5kre

HET: 6wg

MENH_ECOLI_1_252 [text] 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [AB hydrolase superfamily. MenH family]

volume: 163. Å3; shape: 0.6; buriedness: 0.93

negative: 0.; positive: 0.14; polar: 0.22; backbone: 0.31; hydrophobic: 0.33

PDB: 4gdm, 4gec, 4geg, 4mxd, 4myd, 4mys

HET: 164

MGLL_HUMAN_1_303 [text] Monoglyceride lipase [AB hydrolase superfamily. Monoacylglycerol lipase family]

volume: 403. Å3; shape: 0.4; buriedness: 0.84

negative: 0.; positive: 0.14; polar: 0.12; backbone: 0.31; hydrophobic: 0.43

PDB: 3hju, 3jw8, 3jwe, 3pe6, 4uuq

HET: 64d, f4p, mrd, zyh

PAFA_HUMAN_46_428 [text] Platelet-activating factor acetylhydrolase [AB hydrolase superfamily. Lipase family]

volume: 503. Å3; shape: 0.42; buriedness: 0.83

negative: 0.; positive: 0.08; polar: 0.12; backbone: 0.25; hydrophobic: 0.54

PDB: 3d59, 3d5e, 3f96, 3f97, 3f98, 3f9c, 5i8p, 5i9i, 5jad, 5jah, 5jal, 5jan, 5jao, 5jap, 5jar, 5jas, 5jat, 5jau

HET: 5hv, 6ho, 6hp, 6hq, 6hr, 6hu, 6hv, 6hw, 6hx, 6hz, dep, dfp, fb2, gd7, ntj, vq7

PAG15_HUMAN_33_412 [text] Group XV phospholipase A2 [AB hydrolase superfamily. Lipase family]

volume: 324. Å3; shape: 0.55; buriedness: 0.88

negative: 0.05; positive: 0.11; polar: 0.16; backbone: 0.28; hydrophobic: 0.41

PDB: 4x90, 4x91, 4x92, 4x93, 4x94, 4x95, 4x97

HET: ief, may

PNAE_RAUSE_4_264 [text] Polyneuridine-aldehyde esterase [AB hydrolase superfamily]

volume: 198. Å3; shape: 0.55; buriedness: 0.97

negative: 0.; positive: 0.; polar: 0.16; backbone: 0.36; hydrophobic: 0.48

Domains/regions: [D] AB hydrolase-1

PDB: 2wfl, 2wfm, 3gzj

HET: evs

RDMC_STREF_1_298 [text] Aclacinomycin methylesterase RdmC [AB hydrolase superfamily. Hydrolase RdmC family]

volume: 488. Å3; shape: 0.53; buriedness: 0.8

negative: 0.05; positive: 0.; polar: 0.15; backbone: 0.45; hydrophobic: 0.35

Domains/regions: [D] AB hydrolase-1

PDB: 1q0r, 1q0z

HET: aka, akt

RSBQ_BACSU_3_269 [text] Sigma factor SigB regulation protein RsbQ [AB hydrolase superfamily]

volume: 92. Å3; shape: 0.63; buriedness: 0.99

negative: 0.; positive: 0.1; polar: 0.19; backbone: 0.19; hydrophobic: 0.52

PDB: 1wom, 1wpr

HET: pms

SABP2_TOBAC_1_260 [text] Salicylic acid-binding protein 2 [AB hydrolase superfamily. Methylesterase family]

volume: 103. Å3; shape: 0.79; buriedness: 1.

negative: 0.; positive: 0.08; polar: 0.16; backbone: 0.2; hydrophobic: 0.56

PDB: 1xkl, 1y7h, 1y7i

HET: sal, sth