ZAP70_HUMAN_327_607

Tyrosine-protein kinase ZAP-70 [Protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ZAP70_HUMAN):D: Protein kinase (344:349,352,367,369,399,414:417,420,421,465,466,468,478,479)344:349,352,367,369,399,414:417,420,421,465,466,468,478,479
Metals (Me):Mg

Full PDB list

1u59,2ozo,4k2r (redundant pocketome entry)

Contact map

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ligand
A1 Me
L
3
4
4
G
3
4
5
C
3
4
6
G
3
4
7
N
3
4
8
F
3
4
9
V
3
5
2
A
3
6
7
K
3
6
9
V
3
9
9
M
4
1
4
E
4
1
5
M
4
1
6
A
4
1
7
G
4
2
0
P
4
2
1
R
4
6
5
N
4
6
6
L
4
6
8
S
4
7
8
D
4
7
9
[1]1u59.a stu 35 . . . . . . . . . . . . . . . . . . . . .
[1]2ozo.a anp 31 . . . . . . . . . . . . . . . . . . . . . Mg

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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