WEE1_HUMAN_289_575

Wee1-like protein kinase [Protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (WEE1_HUMAN):D: Protein kinase (303,305,306,313,326:328,346,360,374,376:383,386,430,433,463)303,305,306,313,326:328,346,360,374,376:383,386,430,433,463

Full PDB list

1x8b,2in6,2io6,2z2w,3bi6,3biz,3cqe,3cr0

Contact map

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ligand
A1
E
3
0
3
I
3
0
5
G
3
0
6
V
3
1
3
A
3
2
6
I
3
2
7
K
3
2
8
E
3
4
6
V
3
6
0
I
3
7
4
N
3
7
6
E
3
7
7
Y
3
7
8
C
3
7
9
N
3
8
0
G
3
8
1
G
3
8
2
S
3
8
3
D
3
8
6
S
4
3
0
F
4
3
3
D
4
6
3
[1]2io6.a 330 31 . . . . . . . . . . . . . . . . . . . . . .
[1]3biz.a 61e 34 . . . . . . . . . . . . . . . . . . . . . .
[1]2z2w.a 770 28 . . . . . . . . . . . . . . . . . . . . . .
[1]2in6.a 839 30 . . . . . . . . . . . . . . . . . . . . . .
[1]3cqe.a p91 29 . . . . . . . . . . . . . . . . . . . . . .
[1]3cr0.a 809 25 . . . . . . . . . . . . . . . . . . . . . .
[1]3bi6.a 396 37 . . . . . . . . . . . . . . . . . . . . . .
[1]1x8b.a 824 25 . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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