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VGFR2_HUMAN_808_1171

Vascular endothelial growth factor receptor 2 [Protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily]

Composition of the binding site

Protein chains monomer [domain annotation]
A1 (VGFR2_HUMAN):D: Protein kinase (838, 840:843, 846, 848, 850, 866:868, 885, 888, 889, 892, 898, 899, 914, 916:923, 1019, 1024:1027, 1032, 1035, 1044:1051)
801:805, 814
801:805, 814, 838, 840:843, 846, 848, 850, 866:868, 885, 888, 889, 892, 898, 899, 914, 916:923, 1019, 1024:1027, 1032, 1035, 1044:1051

Full PDB list

1vr2, 1y6a, 1y6b, 1ywn, 2oh4, 2p2h, 2p2i, 2qu5, 2qu6, 2rl5, 2xir, 3b8q, 3b8r, 3be2, 3c7q, 3cjf, 3cjg, 3cp9, 3cpb, 3cpc, 3dtw, 3efl, 3ewh, 3u6j, 3vhe, 3vhk, 3vid, 3vnt, 3vo3, 3wzd, 3wze, 4ag8, 4agc, 4agd, 4asd, 4ase, 5ew3 (redundant Pocketome entry)

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1
I
8
0
4
L
8
4
0
G
8
4
1
R
8
4
2
G
8
4
3
V
8
4
8
E
8
5
0
A
8
6
6
V
8
6
7
K
8
6
8
E
8
8
5
I
8
8
8
L
8
8
9
I
8
9
2
V
8
9
8
V
8
9
9
V
9
1
4
V
9
1
6
E
9
1
7
F
9
1
8
C
9
1
9
K
9
2
0
F
9
2
1
G
9
2
2
N
9
2
3
L
1
0
1
9
C
1
0
2
4
I
1
0
2
5
H
1
0
2
6
R
1
0
2
7
L
1
0
3
5
I
1
0
4
4
C
1
0
4
5
D
1
0
4
6
F
1
0
4
7
G
1
0
4
8
L
1
0
4
9
[1]1vr2.a none - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . - -
[1]1y6a.a aaz31 - . . . - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . - -
[1]1y6b.a aax34 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . - -
[1]1ywn.a lif39 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . - - -
[1]2oh4.a gig36 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2p2i.a 60830 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2qu5.a 27632 - . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . .
[1]2qu6.b 85736 - . . . - . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . - -
[1]2rl5.a 2rl35 - . . . - . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . .
[1]2xir.a 00j34 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3b8q.a 90035 - . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . - -
[1]3be2.a raj39 - . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . -
[1]3c7q.a xin40 - . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . . . . - -
[1]3cp9.b c1930 - . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . .
[1]3cpb.a c9227 - . - - - . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . - -
[1]3cpc.b c5229 - . . - - . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . -
[1]3dtw.a a9630 - . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . - -
[1]3efl.a 70628 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]3ewh.a k1139 - . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . .
[1]3u6j.a 03x39 - . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . .
[1]3vhe.a 42q32 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vhk.a bpk22 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vid.a 4tt17 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . - - -
[1]3vnt.a 0ja38 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vo3.a 0kf32 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3wze.a bax32 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4ase.a av932 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]5ew3.a 5t227 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[2]2p2h.a 99432 - . . . - . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . .
[2]3b8r.b 88731 - . . . - . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . .
[2]3cjg.a kim31 - . . . - . . . . . . . . . . . . . . . . . . . . . * . . . . . . . . . .
[2]3wzd.a lev30 - . . - - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[3]4agc.a axi28 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[3]4agd.a b4929 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[4]3cjf.a sav30 - . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . * . - - .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1
Y
8
0
1
L
8
0
2
S
8
0
3
I
8
0
4
V
8
0
5
D
8
1
4
K
8
3
8
L
8
4
0
G
8
4
1
R
8
4
2
G
8
4
3
G
8
4
6
V
8
4
8
E
8
5
0
A
8
6
6
V
8
6
7
K
8
6
8
E
8
8
5
I
8
8
8
L
8
8
9
I
8
9
2
V
8
9
8
V
8
9
9
V
9
1
4
V
9
1
6
E
9
1
7
F
9
1
8
C
9
1
9
K
9
2
0
F
9
2
1
G
9
2
2
N
9
2
3
L
1
0
1
9
C
1
0
2
4
I
1
0
2
5
H
1
0
2
6
R
1
0
2
7
R
1
0
3
2
L
1
0
3
5
I
1
0
4
4
C
1
0
4
5
D
1
0
4
6
F
1
0
4
7
G
1
0
4
8
L
1
0
4
9
A
1
0
5
0
R
1
0
5
1
[1]1vr2.a - - - - - - . . . * . . . . . . * * . . . . . . . . . . . . . . . . . . . . . . . . * - - - -
[1]1y6a.a - - - - - - . . . * - - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * * - - - -
[1]1y6b.a - - - - - - * . . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * * - - - -
[1]1ywn.a - - - - - - * . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . - - - - -
[1]2oh4.a - - - - - - . . . . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . * . * . *
[1]2p2i.a - - - - - - . . . . . . . . . . * * . . . . . . . . . . . . . . . . . . . . . . . . * . . * -
[1]2qu5.a - - - - - - . . . . . . . . . . . * . . . . . . T . . . . . . * . . . . . . . . . * * . . * -
[1]2qu6.b - - - - - - * . . . - - . . . . . * . . . . . . T . . . . . . . . . . . . . . . . . * - - - -
[1]2rl5.a - - - - - - . . . . - . . . . . . * . . . . . . T . . . . . . . . . . . . . . . . . * . . - -
[1]2xir.a - - - - - - . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . * . . * .
[1]3b8q.a - - - - - - * . . . . . . . . . * . . . . . . . T . . . . . . . . . . . . . . . . . * - - - -
[1]3be2.a - - - - - - . . . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . . . - - -
[1]3c7q.a - - - - - - . . . . . . . . . . * * . . . . . . . . . . . . . . . * . . . . . . . . . - - - -
[1]3cp9.b - - - - - - * . . . . . . . . . . * . . . . . . T . . . . . . . . . . . . . . . . . * . * - -
[1]3cpb.a - - - - - - * . - - - - . . . . * * . . . . . . T . . . . . . . . . . . . . . . . . * - - - -
[1]3cpc.b - - - - - - * . . - - - * . . . . . . . . . . . T . . . . . . . . . . . . . . . . . * . - - -
[1]3dtw.a - - - - - - * . . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . * - - - -
[1]3efl.a - - - - - - . . . . . . . . . . * * . . . . . . . . . . . . . . . . . . . . . . . . * . - - -
[1]3ewh.a - - - - - - * . . . . . . . . . . . . . . . . . T . . . . . . . . . . . . . . . . . * . . . .
[1]3u6j.a - - - - - - . . . . . . . . . . * . . . . . . . T . . . . . . . . . . . . . . . . . * . . * .
[1]3vhe.a - - - - - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . * .
[1]3vhk.a - - - - - . . . . . . . . . . . * * . . . . . . . . . . . . . . . . . . . . . . . . * . . * .
[1]3vid.a - - - - - . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . - - - - -
[1]3vnt.a - - - - - . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . * . . * .
[1]3vo3.a - - - - - . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . * . . * .
[1]3wze.a - - - - - - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . * .
[1]4ase.a - - - - - . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . * . . * .
[1]5ew3.a - - - - - - * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . * . - - -
[2]2p2h.a - - - - - - . . . . - - . . . . * . . . . . . . T . . . . . . . . . . . . . . . . . * * * . -
[2]3b8r.b - - - - - - * . . . - . * . . . . . . . . . . . T . . . . . . . . . . . . . . . . . * * * - -
[2]3cjg.a - - - - - - . . . . - . . . . . . . . . . . . . . . . . . . . . . * . . . . . . . . * * * * .
[2]3wzd.a - - - - - - * . . - - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * * * . -
[3]4agc.a . * . * . - * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . * . . * .
[3]4agd.a - * * * * - * . . . . . * . . . * * . . . . . . . . . . . . . . . . . . . . . . . . * . . * .
[4]3cjf.a - - - - - - * . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . . * * - - . * .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
1vr2.a is apo
1y6a.a:aaz
1y6b.a:aax
1ywn.a:lif
2oh4.a:gig
2p2i.a:608
2qu5.a:276
2qu6.b:857
2rl5.a:2rl
2xir.a:00j
3b8q.a:900
3be2.a:raj
3c7q.a:xin
3cp9.b:c19
3cpb.a:c92
3cpc.b:c52
3dtw.a:a96
3efl.a:706
3ewh.a:k11
3u6j.a:03x
3vhe.a:42q
3vhk.a:bpk
3vid.a:4tt
3vnt.a:0ja
3vo3.a:0kf
3wze.a:bax
4ase.a:av9
5ew3.a:5t2
2p2h.a:994
3b8r.b:887
3cjg.a:kim
3wzd.a:lev
4agc.a:axi
4agd.a:b49
3cjf.a:sav
[1] 1vr2.a
-
0.2 2.4 6.7 6.3 5.1 6.7 6.4 6.0 2.3 4.2 7.5 0.4 7.8 5.7 5.4 6.6 6.1 7.4 7.8 6.3 5.7 0 7.5 4.7 6.4 5.1 6.5 2.4 2.5 2.0 2.4 2.2 0.2 0
[1] 1y6a.a -
0
0 8.8 8.4 7.2 7.4 8.3 7.9 4.6 6.3 7.9 2.3 8.4 8.1 9.2 7.6 6.7 8.3 8.5 8.1 7.4 0 8.2 6.5 7.5 7.3 8.9 1.1 5.1 0.4 5.5 4.5 0.5 0.2
[1] 1y6b.a - 0.1
0.1
9.2 7.7 8.2 7.1 7.8 7.5 4.1 6.2 8.0 3.5 9.3 6.4 9.1 7.1 7.0 6.7 8.4 7.6 7.5 0 7.8 6.1 7.7 6.5 8.7 1.9 4.6 0.6 3.7 4.2 0.9 0
[1] 1ywn.a - 0.1 0.2
0
0.5 0.8 0.9 1.6 0.9 0.7 0.3 0.6 0.9 0.6 1.0 1.1 0.4 0.6 0.8 1.4 0.4 0.4 0.2 0.7 0.5 0.4 0.6 0.3 0.5 0.7 0.5 0.5 0.5 0.2 0.3
[1] 2oh4.a - 3.5 1.9 2.5
0.1
0.9 0.9 1.2 0.5 0.4 0.3 0.4 0.8 1.1 0.8 1.2 0.4 0.8 0.5 1.6 0.2 0.7 0.1 0.8 0.4 0.4 0.6 0.5 1.4 0.6 0.6 0.5 0.5 0.5 3.8
[1] 2p2i.a - 4.3 3.0 3.3 0.9
0
0.2 0.5 2.1 0.4 0.8 3.4 3.0 0.5 0.2 0.6 0.4 0 2.5 3.0 1.7 0.8 1.2 0.2 0.4 0.4 1.4 0.4 2.7 1.7 2.8 1.7 0.5 1.0 3.9
[1] 2qu5.a - 4.3 3.0 4.0 1.1 0.4
0
0.8 2.1 0.6 0.6 3.6 1.7 0.6 0.3 0.6 0.3 0.2 2.3 2.6 1.4 0.8 1.2 0.5 0 0.2 1.1 0.2 2.9 1.1 2.6 1.1 0.7 0.7 3.6
[1] 2qu6.b - 3.9 1.9 2.7 0.6 0.1 0.1
0
0.8 0.4 0.4 1.8 2.0 0.4 0.2 0.6 0.3 0.1 2.0 2.2 1.0 0.6 0.9 0.3 0 0.1 0.8 0.2 2.4 1.0 2.2 0.9 0.8 0.2 3.3
[1] 2rl5.a - 2.1 0.7 0.7 0.2 0.3 0.3 0.4
0
0.2 0 0.6 0.2 0.1 0.1 0.4 0.1 0.1 0.5 1.2 0.1 0.2 0 0.4 0.1 0.1 0.1 0.1 1.0 0.4 0.2 0.2 0.1 0 2.1
[1] 2xir.a - 3.9 2.1 3.5 0.3 0.1 0.1 0.2 0.5
0.1
0.3 1.3 0.8 0.2 0.2 0.3 0.2 0.3 1.2 1.4 0.3 0.1 0.3 0.1 0 0 0.2 0.2 2.2 0.5 1.8 0.4 0.3 0.1 3.3
[1] 3b8q.a - 2.9 1.7 2.0 0.4 0.2 0.1 0.1 0.2 0.2
0
1.2 1.6 0.4 0 0.3 0 0.2 1.2 0.8 0.3 0.4 0.2 0.3 0 0.1 0 0.2 1.9 0.1 1.9 0.1 0.3 0.2 3.1
[1] 3be2.a - 0.9 0.6 0.4 0.3 0.2 0.2 0.5 0.7 0.4 0.3
0
0.7 0.2 0.1 0.5 0 0.2 0.3 1.4 0.5 0.9 0 0.3 0.1 0.3 0.6 0.2 0.8 0.5 0.3 0.6 0.4 0.4 1.0
[1] 3c7q.a - 0.3 1.2 0.8 0.8 1.2 0.8 1.2 0.7 0.7 0.6 1.2
0
0.6 0.8 1.6 0.6 1.0 2.0 1.9 1.2 0.3 0.1 0.5 0.2 0.4 1.0 1.1 0.4 1.2 1.6 0.9 0.6 0 0.1
[1] 3cp9.b - 3.5 2.2 3.4 0.4 0.3 0.1 0.4 1.0 0.2 0.5 1.3 2.6
0
0 0.2 0.1 0 1.5 1.9 0.4 0.1 0.2 0 0 0.2 1.1 0 1.5 0.7 1.5 0.5 0 0.4 3.9
[1] 3cpb.a - 3.6 2.1 2.1 0.8 0.3 0.1 0.2 0.6 0.1 0.1 1.4 2.3 0.5
0
0.4 0.1 0.2 1.3 1.4 0.3 0.6 0.6 0.3 0.1 0 0.2 0.3 2.3 0.3 1.8 0.4 0.7 0.2 3.1
[1] 3cpc.b - 4.1 2.6 2.2 0.6 0 0.3 0.8 1.2 0.3 0.9 2.0 2.7 0 0
0
0 0.1 1.8 1.6 0.7 0 0.6 0.2 0 0.3 1.0 0 1.5 0.7 1.9 0.8 0 0.4 3.5
[1] 3dtw.a - 2.8 1.5 2.1 0.6 0.4 0.4 0.6 0.4 0.4 0.3 1.0 2.0 0.7 0.1 0.4
0
0.4 0.9 0.7 0.3 0.5 0.3 0.4 0.2 0.1 0.3 0.2 2.0 0.1 1.1 0 0.8 0.2 3.2
[1] 3efl.a - 3.4 2.4 2.2 0.4 0.4 0.3 0.9 1.6 0.4 0.6 1.3 2.2 0.3 0.2 0.3 0.1
0
1.9 2.2 1.0 0.4 0.7 0.1 0.1 0.4 1.2 0 2.2 1.1 2.4 0.9 0.2 0.5 3.1
[1] 3ewh.a - 2.0 0.9 0.5 0.1 0.5 0.5 0.7 0.2 0.3 0.1 0.4 1.2 0.4 0.1 0.5 0 0.2
0
0.9 0.2 0.5 0.1 0.2 0.1 0.2 0.2 0.2 1.0 0.4 0.5 0.1 0.1 0.2 1.9
[1] 3u6j.a - 2.8 1.3 1.9 0.5 0.6 0.4 0.9 0.2 0.4 0.1 1.0 0.3 0.3 0.4 0.4 0 0.3 1.0
0
0.2 0.3 0.2 0.4 0.1 0.1 0.3 0.2 1.8 0.3 1.5 0.1 0.4 0 2.4
[1] 3vhe.a - 3.7 2.4 2.8 0.3 0.6 0.5 0.4 0.6 0.1 0.4 0.7 0.8 0.4 0.1 0.5 0.2 0.6 1.0 1.4
0
0.2 0.1 0.6 0.4 0.1 0.4 0.4 1.0 0.3 1.4 0.5 0.4 0.2 3.3
[1] 3vhk.a - 3.7 2.8 4.4 0.9 0.5 0.4 0.7 0.5 0.1 0.5 2.3 1.1 0.3 0.5 0.9 0.6 0.4 2.2 1.8 0.8
0
0.3 0.9 0.5 0.4 0.4 0.7 1.6 1.1 2.0 0.7 0.2 0.1 3.4
[1] 3vid.a - 0.1 0.5 1.1 0.4 0.5 0.6 1.0 0.4 0.6 0.5 0.8 0 0.3 0.7 0.6 0.5 0.5 1.1 1.6 0.5 0.1
0
0.4 0.3 0.2 0.7 0.3 0.5 0.9 0.9 0.6 0.3 0.2 0.2
[1] 3vnt.a - 4.8 3.6 5.4 0.3 0.3 0.2 0.4 0.6 0.2 0.3 2.3 1.9 0.4 0.1 0.4 0.1 0.2 2.3 1.6 0.3 0.6 0.4
0
0 0 0.7 0.1 1.8 0.5 2.1 0.3 0.2 0.1 3.1
[1] 3vo3.a - 4.9 3.8 6.0 0.4 0.2 0.3 0.5 0.6 0.2 0.3 2.6 1.0 0.5 0.2 0.4 0.4 0.2 2.2 1.9 0.4 0.8 0.4 0.1
0
0 0.8 0 2.0 0.6 2.3 0.3 0.3 0.3 3.3
[1] 3wze.a - 3.8 2.1 3.6 0.4 0.4 0.1 0.4 0.8 0.2 0.4 1.3 0.8 0.6 0.2 0.5 0.3 0.3 1.2 1.6 0.5 0.8 0.6 0.2 0
0
0.4 0.1 2.3 0.5 1.5 0.4 0.4 0.3 3.1
[1] 4ase.a - 3.2 1.6 3.1 0.1 0.2 0.2 0.3 0.5 0.1 0.2 1.3 0.9 0.5 0.1 0.4 0.2 0.3 1.0 1.2 0.2 0.7 0.2 0.3 0.1 0.1
0
0.1 1.8 0.5 1.4 0.3 0.5 0.1 3.1
[1] 5ew3.a - 4.1 2.1 3.1 0.9 0.4 0.5 0.9 1.6 0.7 1.1 2.5 2.7 0.5 0.4 0.4 0.2 0.2 2.8 2.7 1.1 0.5 0.7 0.6 0.1 0.5 1.8
0
2.2 1.0 2.3 0.8 0.5 0.5 3.4
[2] 2p2h.a - 0.1 0.4 8.4 7.4 4.1 7.3 8.0 5.1 0.6 4.9 11 0.1 5.5 4.9 3.6 7.3 6.1 6.6 8.3 7.1 6.4 0 7.0 3.4 8.4 4.3 5.1
0.1
1.7 1.0 1.3 0.1 0.1 0
[2] 3b8r.b - 0.2 0.6 4.2 4.8 6.5 4.4 8.1 4.7 0.2 3.7 7.5 0.9 4.4 3.6 2.2 4.1 5.2 4.4 5.3 4.6 5.1 0 5.0 0.9 4.3 3.2 3.0 0.1
0
0.9 0.1 0.1 0 0.1
[2] 3cjg.a - 0.2 0.3 6.4 6.0 5.1 6.6 11 5.1 0.6 5.0 8.6 0.1 4.6 4.9 5.0 5.4 5.0 5.3 5.9 5.8 6.0 0.1 5.4 3.9 6.1 5.2 5.7 0.3 1.3
0
1.3 0.5 0 0.3
[2] 3wzd.a - 0.5 0.6 4.4 4.7 6.2 4.3 7.7 4.3 0.3 3.6 7.5 1.6 4.9 4.5 2.8 4.1 4.7 3.8 6.1 4.1 5.6 0.1 5.3 1.2 4.2 3.6 3.1 0.4 0.4 0.3
0
0.3 0.1 0.9
[3] 4agc.a - 3.8 2.3 4.5 2.8 4.3 2.0 5.3 2.3 0.1 2.4 4.0 1.9 1.4 1.5 0.5 1.6 2.0 2.9 3.7 1.8 2.9 0.2 1.4 0.4 2.1 1.6 0.5 1.1 0.7 1.7 0.6
0
0.1 3.2
[3] 4agd.a - 3.4 4.2 6.0 4.4 6.0 3.8 7.6 4.6 1.9 4.1 7.7 1.9 3.6 3.7 2.5 3.5 3.8 5.4 4.3 2.7 3.7 0.1 3.4 1.9 3.6 3.1 2.3 2.9 2.4 3.2 2.8 1.9
0
3.2
[4] 3cjf.a - 0 0.1 2.8 2.7 5.2 3.4 7.1 3.1 0.4 2.3 3.3 1.1 3.7 2.5 4.3 2.9 2.8 2.8 3.2 3.1 4.4 0 3.4 2.5 3.6 2.4 4.6 0.3 0.5 0 0.5 0.5 0.2
0
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (4 clusters)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
1vr2.a
1y6a.a
1y6b.a
1ywn.a
2oh4.a
2p2i.a
2qu5.a
2qu6.b
2rl5.a
2xir.a
3b8q.a
3be2.a
3c7q.a
3cp9.b
3cpb.a
3cpc.b
3dtw.a
3efl.a
3ewh.a
3u6j.a
3vhe.a
3vhk.a
3vid.a
3vnt.a
3vo3.a
3wze.a
4ase.a
5ew3.a
2p2h.a
3b8r.b
3cjg.a
3wzd.a
4agc.a
4agd.a
3cjf.a
[1] 1vr2.a
0
.17 .21 .24 .26 .20 .22 .17 .18 .20 .19 .21 .19 .20 .19 .18 .19 .16 .21 .20 .20 .20 .18 .17 .16 .19 .21 .18 .21 .26 .23 .28 .34 .33 .39
[1] 1y6a.a .17
0
.09 .27 .29 .25 .24 .21 .21 .26 .24 .24 .26 .25 .24 .22 .22 .21 .24 .26 .26 .27 .23 .24 .23 .25 .26 .22 .29 .33 .28 .33 .40 .45 .25
[1] 1y6b.a .21 .09
0
.30 .35 .28 .30 .24 .28 .33 .26 .29 .31 .27 .25 .24 .23 .26 .27 .32 .33 .34 .30 .26 .29 .32 .31 .24 .33 .34 .33 .32 .44 .47 .27
[1] 1ywn.a .24 .27 .30
0
.18 .23 .26 .16 .11 .21 .15 .08 .11 .22 .16 .19 .14 .16 .09 .18 .21 .24 .09 .21 .25 .21 .18 .20 .37 .32 .33 .30 .35 .39 .20
[1] 2oh4.a .26 .29 .35 .18
0
.27 .27 .21 .13 .21 .21 .15 .21 .21 .21 .24 .20 .21 .15 .21 .20 .26 .19 .24 .24 .20 .22 .25 .30 .30 .29 .29 .38 .45 .32
[1] 2p2i.a .20 .25 .28 .23 .27
0
.11 .09 .18 .10 .13 .21 .22 .14 .11 .12 .17 .11 .18 .16 .12 .11 .24 .07 .09 .11 .09 .15 .30 .24 .24 .30 .24 .29 .29
[1] 2qu5.a .22 .24 .30 .26 .27 .11
0
.13 .17 .11 .16 .21 .22 .18 .13 .16 .17 .14 .20 .17 .12 .11 .22 .15 .14 .11 .13 .17 .31 .30 .27 .36 .27 .33 .33
[1] 2qu6.b .17 .21 .24 .16 .21 .09 .13
0
.11 .12 .07 .15 .17 .09 .06 .08 .11 .06 .11 .15 .13 .14 .17 .10 .13 .12 .10 .09 .27 .21 .28 .27 .25 .32 .30
[1] 2rl5.a .18 .21 .28 .11 .13 .18 .17 .11
0
.13 .10 .06 .13 .17 .12 .16 .10 .12 .08 .11 .13 .17 .10 .18 .18 .13 .11 .17 .29 .27 .26 .29 .31 .37 .28
[1] 2xir.a .20 .26 .33 .21 .21 .10 .11 .12 .13
0
.11 .16 .19 .18 .10 .16 .14 .13 .14 .11 .03 .06 .19 .07 .07 .03 .04 .18 .30 .27 .24 .32 .21 .29 .27
[1] 3b8q.a .19 .24 .26 .15 .21 .13 .16 .07 .10 .11
0
.13 .17 .11 .04 .09 .06 .09 .09 .11 .12 .15 .18 .12 .16 .13 .08 .12 .29 .21 .29 .25 .25 .31 .28
[1] 3be2.a .21 .24 .29 .08 .15 .21 .21 .15 .06 .16 .13
0
.12 .20 .14 .18 .11 .15 .07 .14 .16 .20 .09 .20 .21 .17 .14 .20 .32 .30 .28 .29 .33 .40 .23
[1] 3c7q.a .19 .26 .31 .11 .21 .22 .22 .17 .13 .19 .17 .12
0
.21 .18 .19 .19 .15 .16 .16 .20 .18 .08 .22 .21 .20 .19 .19 .32 .32 .34 .37 .34 .35 .25
[1] 3cp9.b .20 .25 .27 .22 .21 .14 .18 .09 .17 .18 .11 .20 .21
0
.11 .08 .13 .09 .17 .20 .18 .19 .21 .14 .17 .17 .17 .09 .25 .19 .27 .25 .26 .35 .33
[1] 3cpb.a .19 .24 .25 .16 .21 .11 .13 .06 .12 .10 .04 .14 .18 .11
0
.09 .06 .09 .09 .14 .12 .13 .18 .12 .15 .11 .10 .11 .29 .21 .29 .25 .25 .31 .30
[1] 3cpc.b .18 .22 .24 .19 .24 .12 .16 .08 .16 .16 .09 .18 .19 .08 .09
0
.09 .08 .14 .15 .17 .16 .20 .12 .14 .16 .16 .08 .27 .20 .26 .25 .26 .32 .29
[1] 3dtw.a .19 .22 .23 .14 .20 .17 .17 .11 .10 .14 .06 .11 .19 .13 .06 .09
0
.11 .10 .12 .14 .18 .16 .15 .19 .15 .12 .12 .29 .22 .25 .21 .28 .34 .27
[1] 3efl.a .16 .21 .26 .16 .21 .11 .14 .06 .12 .13 .09 .15 .15 .09 .09 .08 .11
0
.13 .14 .13 .13 .17 .12 .14 .12 .12 .08 .26 .24 .28 .29 .24 .31 .30
[1] 3ewh.a .21 .24 .27 .09 .15 .18 .20 .11 .08 .14 .09 .07 .16 .17 .09 .14 .10 .13
0
.12 .15 .19 .14 .16 .19 .16 .12 .16 .32 .26 .29 .26 .29 .36 .25
[1] 3u6j.a .20 .26 .32 .18 .21 .16 .17 .15 .11 .11 .11 .14 .16 .20 .14 .15 .12 .14 .12
0
.11 .14 .16 .15 .15 .12 .10 .17 .29 .26 .23 .29 .28 .33 .27
[1] 3vhe.a .20 .26 .33 .21 .20 .12 .12 .13 .13 .03 .12 .16 .20 .18 .12 .17 .14 .13 .15 .11
0
.08 .18 .09 .07 .03 .05 .18 .30 .29 .23 .33 .20 .28 .28
[1] 3vhk.a .20 .27 .34 .24 .26 .11 .11 .14 .17 .06 .15 .20 .18 .19 .13 .16 .18 .13 .19 .14 .08
0
.21 .10 .08 .06 .09 .17 .31 .29 .25 .34 .22 .26 .30
[1] 3vid.a .18 .23 .30 .09 .19 .24 .22 .17 .10 .19 .18 .09 .08 .21 .18 .20 .16 .17 .14 .16 .18 .21
0
.22 .22 .18 .18 .20 .30 .32 .31 .35 .34 .39 .25
[1] 3vnt.a .17 .24 .26 .21 .24 .07 .15 .10 .18 .07 .12 .20 .22 .14 .12 .12 .15 .12 .16 .15 .09 .10 .22
0
.04 .08 .08 .14 .27 .24 .22 .28 .20 .28 .27
[1] 3vo3.a .16 .23 .29 .25 .24 .09 .14 .13 .18 .07 .16 .21 .21 .17 .15 .14 .19 .14 .19 .15 .07 .08 .22 .04
0
.06 .09 .17 .26 .27 .20 .31 .23 .30 .30
[1] 3wze.a .19 .25 .32 .21 .20 .11 .11 .12 .13 .03 .13 .17 .20 .17 .11 .16 .15 .12 .16 .12 .03 .06 .18 .08 .06
0
.05 .17 .29 .28 .22 .32 .20 .27 .27
[1] 4ase.a .21 .26 .31 .18 .22 .09 .13 .10 .11 .04 .08 .14 .19 .17 .10 .16 .12 .12 .12 .10 .05 .09 .18 .08 .09 .05
0
.17 .31 .26 .24 .31 .21 .28 .26
[1] 5ew3.a .18 .22 .24 .20 .25 .15 .17 .09 .17 .18 .12 .20 .19 .09 .11 .08 .12 .08 .16 .17 .18 .17 .20 .14 .17 .17 .17
0
.28 .25 .30 .27 .26 .31 .32
[2] 2p2h.a .21 .29 .33 .37 .30 .30 .31 .27 .29 .30 .29 .32 .32 .25 .29 .27 .29 .26 .32 .29 .30 .31 .30 .27 .26 .29 .31 .28
0
.13 .18 .19 .44 .51 .48
[2] 3b8r.b .26 .33 .34 .32 .30 .24 .30 .21 .27 .27 .21 .30 .32 .19 .21 .20 .22 .24 .26 .26 .29 .29 .32 .24 .27 .28 .26 .25 .13
0
.21 .09 .40 .47 .43
[2] 3cjg.a .23 .28 .33 .33 .29 .24 .27 .28 .26 .24 .29 .28 .34 .27 .29 .26 .25 .28 .29 .23 .23 .25 .31 .22 .20 .22 .24 .30 .18 .21
0
.22 .39 .44 .35
[2] 3wzd.a .28 .33 .32 .30 .29 .30 .36 .27 .29 .32 .25 .29 .37 .25 .25 .25 .21 .29 .26 .29 .33 .34 .35 .28 .31 .32 .31 .27 .19 .09 .22
0
.45 .50 .42
[3] 4agc.a .34 .40 .44 .35 .38 .24 .27 .25 .31 .21 .25 .33 .34 .26 .25 .26 .28 .24 .29 .28 .20 .22 .34 .20 .23 .20 .21 .26 .44 .40 .39 .45
0
.14 .40
[3] 4agd.a .33 .45 .47 .39 .45 .29 .33 .32 .37 .29 .31 .40 .35 .35 .31 .32 .34 .31 .36 .33 .28 .26 .39 .28 .30 .27 .28 .31 .51 .47 .44 .50 .14
0
.43
[4] 3cjf.a .39 .25 .27 .20 .32 .29 .33 .30 .28 .27 .28 .23 .25 .33 .30 .29 .27 .30 .25 .27 .28 .30 .25 .27 .30 .27 .26 .32 .48 .43 .35 .42 .40 .43
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 1.7 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
1vr2.a
1y6a.a
1y6b.a
1ywn.a
2oh4.a
2p2i.a
2qu5.a
2qu6.b
2rl5.a
2xir.a
3b8q.a
3be2.a
3c7q.a
3cp9.b
3cpb.a
3cpc.b
3dtw.a
3efl.a
3ewh.a
3u6j.a
3vhe.a
3vhk.a
3vid.a
3vnt.a
3vo3.a
3wze.a
4ase.a
5ew3.a
2p2h.a
3b8r.b
3cjg.a
3wzd.a
4agc.a
4agd.a
3cjf.a
[1] 1vr2.a
0
1.1 1.3 0.8 1.6 2.3 2.4 2.1 1.8 1.9 1.9 1.8 1.3 2.0 2.1 2.2 1.9 2.1 1.9 1.7 1.9 2.0 0.6 1.9 1.9 1.9 1.9 2.1 0.5 1.0 0.9 1.2 1.9 1.9 0.8
[1] 1y6a.a 1.1
0
0.5 0.9 1.1 1.9 1.9 1.7 1.3 1.5 1.4 1.1 0.9 1.6 1.6 1.6 1.4 1.7 1.2 1.2 1.4 1.6 0.9 1.4 1.4 1.4 1.4 1.6 1.1 1.2 1.0 1.3 1.4 1.4 0.7
[1] 1y6b.a 1.3 0.5
0
1.2 1.5 2.2 2.3 1.8 1.4 1.9 1.8 1.6 1.2 1.9 1.7 1.8 1.7 1.9 1.7 1.6 1.9 2.0 1.2 1.9 1.9 1.9 1.9 2.0 0.9 1.1 0.9 1.4 1.9 1.8 1.1
[1] 1ywn.a 0.8 0.9 1.2
0
0.5 1.5 1.5 1.3 0.6 1.1 1.0 0.8 0.6 1.1 1.1 1.2 0.9 1.2 0.9 0.7 1.0 1.1 0.8 1.0 1.0 1.0 1.0 1.2 0.9 0.9 0.7 1.2 1.0 1.0 0.9
[1] 2oh4.a 1.6 1.1 1.5 0.5
0
2.3 2.2 1.0 1.1 1.3 0.7 0.8 0.8 1.0 0.9 1.1 0.8 1.1 2.1 1.4 1.3 1.4 0.6 1.3 1.3 1.3 1.3 1.0 3.3 2.5 4.9 3.2 1.3 1.4 4.5
[1] 2p2i.a 2.3 1.9 2.2 1.5 2.3
0
0.7 0.5 1.8 2.1 0.9 1.4 1.7 1.0 0.8 0.7 1.0 0.7 2.2 2.1 2.1 2.1 1.3 2.1 2.1 2.1 2.1 0.8 2.7 2.6 2.8 3.1 2.1 2.1 2.2
[1] 2qu5.a 2.4 1.9 2.3 1.5 2.2 0.7
0
0.7 1.7 2.1 0.9 1.4 1.8 1.0 0.8 0.8 0.9 0.8 2.0 2.1 2.1 2.1 1.4 2.1 2.1 2.0 2.1 0.7 2.8 2.5 2.8 3.0 2.1 2.1 2.3
[1] 2qu6.b 2.1 1.7 1.8 1.3 1.0 0.5 0.7
0
1.0 0.6 0.6 1.0 1.4 0.5 0.6 0.4 0.7 0.5 1.1 1.0 0.8 0.6 1.0 0.6 0.7 0.6 0.7 0.7 2.0 1.7 1.8 2.0 0.8 0.9 1.2
[1] 2rl5.a 1.8 1.3 1.4 0.6 1.1 1.8 1.7 1.0
0
1.4 0.6 0.7 0.9 1.5 0.8 1.0 0.6 1.1 0.7 1.4 1.4 1.5 0.8 1.4 1.5 1.4 1.4 1.1 2.7 2.3 2.2 2.5 1.5 1.5 1.7
[1] 2xir.a 1.9 1.5 1.9 1.1 1.3 2.1 2.1 0.6 1.4
0
0.5 1.1 1.2 0.7 0.6 0.7 0.7 0.9 2.5 0.7 0.3 0.3 0.9 0.3 0.4 0.2 0.4 0.8 3.5 2.6 4.8 3.5 0.5 0.6 4.4
[1] 3b8q.a 1.9 1.4 1.8 1.0 0.7 0.9 0.9 0.6 0.6 0.5
0
0.8 1.1 0.6 0.5 0.6 0.4 0.7 1.0 0.7 0.6 0.6 0.9 0.5 0.6 0.5 0.5 0.8 1.8 1.4 1.5 1.8 0.7 0.7 1.1
[1] 3be2.a 1.8 1.1 1.6 0.8 0.8 1.4 1.4 1.0 0.7 1.1 0.8
0
1.0 1.1 0.8 1.1 0.8 1.1 0.4 0.9 1.1 1.2 1.0 1.1 1.1 1.0 1.1 1.2 2.2 2.0 1.7 2.3 1.1 1.2 0.9
[1] 3c7q.a 1.3 0.9 1.2 0.6 0.8 1.7 1.8 1.4 0.9 1.2 1.1 1.0
0
1.3 1.3 1.4 1.1 1.5 1.2 0.9 1.1 1.2 0.5 1.1 1.1 1.1 1.1 1.4 1.2 1.2 1.1 1.4 1.1 1.1 0.8
[1] 3cp9.b 2.0 1.6 1.9 1.1 1.0 1.0 1.0 0.5 1.5 0.7 0.6 1.1 1.3
0
0.6 0.4 0.7 0.6 1.6 1.0 0.8 0.7 1.0 0.6 0.6 0.6 0.8 0.6 2.9 2.7 2.7 3.0 0.7 0.8 2.2
[1] 3cpb.a 2.1 1.6 1.7 1.1 0.9 0.8 0.8 0.6 0.8 0.6 0.5 0.8 1.3 0.6
0
0.6 0.5 0.7 0.8 0.9 0.7 0.6 1.1 0.7 0.7 0.6 0.6 0.8 2.0 1.6 1.7 1.8 0.8 0.9 1.3
[1] 3cpc.b 2.2 1.6 1.8 1.2 1.1 0.7 0.8 0.4 1.0 0.7 0.6 1.1 1.4 0.4 0.6
0
0.6 0.4 1.1 1.1 0.8 0.6 1.0 0.6 0.7 0.6 0.8 0.7 2.6 2.5 2.2 2.7 0.7 0.9 1.2
[1] 3dtw.a 1.9 1.4 1.7 0.9 0.8 1.0 0.9 0.7 0.6 0.7 0.4 0.8 1.1 0.7 0.5 0.6
0
0.7 0.8 0.7 0.8 0.8 0.9 0.7 0.8 0.7 0.7 0.7 1.8 1.4 1.5 1.8 0.7 0.8 1.1
[1] 3efl.a 2.1 1.7 1.9 1.2 1.1 0.7 0.8 0.5 1.1 0.9 0.7 1.1 1.5 0.6 0.7 0.4 0.7
0
1.2 1.1 1.0 0.9 1.1 0.8 0.8 0.8 0.9 0.7 2.5 2.3 2.1 2.6 0.9 1.0 1.2
[1] 3ewh.a 1.9 1.2 1.7 0.9 2.1 2.2 2.0 1.1 0.7 2.5 1.0 0.4 1.2 1.6 0.8 1.1 0.8 1.2
0
2.4 2.5 2.6 1.2 2.5 2.5 2.5 2.5 1.2 3.0 2.4 3.8 2.8 2.5 2.5 3.4
[1] 3u6j.a 1.7 1.2 1.6 0.7 1.4 2.1 2.1 1.0 1.4 0.7 0.7 0.9 0.9 1.0 0.9 1.1 0.7 1.1 2.4
0
0.7 0.8 0.8 0.8 0.8 0.7 0.6 1.0 3.2 2.4 4.4 3.2 0.7 0.7 4.0
[1] 3vhe.a 1.9 1.4 1.9 1.0 1.3 2.1 2.1 0.8 1.4 0.3 0.6 1.1 1.1 0.8 0.7 0.8 0.8 1.0 2.5 0.7
0
0.5 1.7 0.5 0.4 0.3 0.4 0.9 3.5 2.6 4.7 3.4 0.5 0.6 4.3
[1] 3vhk.a 2.0 1.6 2.0 1.1 1.4 2.1 2.1 0.6 1.5 0.3 0.6 1.2 1.2 0.7 0.6 0.6 0.8 0.9 2.6 0.8 0.5
0
1.7 0.3 0.4 0.3 0.5 0.8 3.6 2.7 4.8 3.6 0.5 0.6 4.4
[1] 3vid.a 0.6 0.9 1.2 0.8 0.6 1.3 1.4 1.0 0.8 0.9 0.9 1.0 0.5 1.0 1.1 1.0 0.9 1.1 1.2 0.8 1.7 1.7
0
1.6 1.7 0.9 1.5 1.1 0.6 0.9 0.8 1.1 0.8 0.8 0.9
[1] 3vnt.a 1.9 1.4 1.9 1.0 1.3 2.1 2.1 0.6 1.4 0.3 0.5 1.1 1.1 0.6 0.7 0.6 0.7 0.8 2.5 0.8 0.5 0.3 1.6
0
0.2 0.3 0.4 0.7 3.5 2.6 4.8 3.5 0.5 0.6 4.3
[1] 3vo3.a 1.9 1.4 1.9 1.0 1.3 2.1 2.1 0.7 1.5 0.4 0.6 1.1 1.1 0.6 0.7 0.7 0.8 0.8 2.5 0.8 0.4 0.4 1.7 0.2
0
0.3 0.5 0.7 3.5 2.6 4.8 3.5 0.5 0.6 4.3
[1] 3wze.a 1.9 1.4 1.9 1.0 1.3 2.1 2.0 0.6 1.4 0.2 0.5 1.0 1.1 0.6 0.6 0.6 0.7 0.8 2.5 0.7 0.3 0.3 0.9 0.3 0.3
0
0.4 0.8 3.5 2.6 4.8 3.5 0.5 0.6 4.3
[1] 4ase.a 1.9 1.4 1.9 1.0 1.3 2.1 2.1 0.7 1.4 0.4 0.5 1.1 1.1 0.8 0.6 0.8 0.7 0.9 2.5 0.6 0.4 0.5 1.5 0.4 0.5 0.4
0
0.9 3.5 2.6 4.7 3.4 0.6 0.6 4.3
[1] 5ew3.a 2.1 1.6 2.0 1.2 1.0 0.8 0.7 0.7 1.1 0.8 0.8 1.2 1.4 0.6 0.8 0.7 0.7 0.7 1.2 1.0 0.9 0.8 1.1 0.7 0.7 0.8 0.9
0
2.3 2.2 1.9 2.5 0.8 0.9 1.2
[2] 2p2h.a 0.5 1.1 0.9 0.9 3.3 2.7 2.8 2.0 2.7 3.5 1.8 2.2 1.2 2.9 2.0 2.6 1.8 2.5 3.0 3.2 3.5 3.6 0.6 3.5 3.5 3.5 3.5 2.3
0
1.3 1.6 1.6 3.5 3.4 1.5
[2] 3b8r.b 1.0 1.2 1.1 0.9 2.5 2.6 2.5 1.7 2.3 2.6 1.4 2.0 1.2 2.7 1.6 2.5 1.4 2.3 2.4 2.4 2.6 2.7 0.9 2.6 2.6 2.6 2.6 2.2 1.3
0
1.1 1.0 2.6 2.6 1.2
[2] 3cjg.a 0.9 1.0 0.9 0.7 4.9 2.8 2.8 1.8 2.2 4.8 1.5 1.7 1.1 2.7 1.7 2.2 1.5 2.1 3.8 4.4 4.7 4.8 0.8 4.8 4.8 4.8 4.7 1.9 1.6 1.1
0
1.6 4.7 4.6 0.9
[2] 3wzd.a 1.2 1.3 1.4 1.2 3.2 3.1 3.0 2.0 2.5 3.5 1.8 2.3 1.4 3.0 1.8 2.7 1.8 2.6 2.8 3.2 3.4 3.6 1.1 3.5 3.5 3.5 3.4 2.5 1.6 1.0 1.6
0
3.5 3.4 1.8
[3] 4agc.a 1.9 1.4 1.9 1.0 1.3 2.1 2.1 0.8 1.5 0.5 0.7 1.1 1.1 0.7 0.8 0.7 0.7 0.9 2.5 0.7 0.5 0.5 0.8 0.5 0.5 0.5 0.6 0.8 3.5 2.6 4.7 3.5
0
0.4 4.3
[3] 4agd.a 1.9 1.4 1.8 1.0 1.4 2.1 2.1 0.9 1.5 0.6 0.7 1.2 1.1 0.8 0.9 0.9 0.8 1.0 2.5 0.7 0.6 0.6 0.8 0.6 0.6 0.6 0.6 0.9 3.4 2.6 4.6 3.4 0.4
0
4.2
[4] 3cjf.a 0.8 0.7 1.1 0.9 4.5 2.2 2.3 1.2 1.7 4.4 1.1 0.9 0.8 2.2 1.3 1.2 1.1 1.2 3.4 4.0 4.3 4.4 0.9 4.3 4.3 4.3 4.3 1.2 1.5 1.2 0.9 1.8 4.3 4.2
0
[Binding site backbone RMSD matrix]

Site full-atom RMSD (median 1.1 Å)

Pockets (x) vs pockets (y) colored by RMSD of all site residue atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
1vr2.a
1y6a.a
1y6b.a
1ywn.a
2oh4.a
2p2i.a
2qu5.a
2qu6.b
2rl5.a
2xir.a
3b8q.a
3be2.a
3c7q.a
3cp9.b
3cpb.a
3cpc.b
3dtw.a
3efl.a
3ewh.a
3u6j.a
3vhe.a
3vhk.a
3vid.a
3vnt.a
3vo3.a
3wze.a
4ase.a
5ew3.a
2p2h.a
3b8r.b
3cjg.a
3wzd.a
4agc.a
4agd.a
3cjf.a
[1] 1vr2.a
0
1.7 1.8 1.4 2.3 2.9 2.9 2.7 2.4 2.5 2.5 2.2 2.3 2.6 2.7 2.7 2.5 2.7 2.4 2.4 2.5 2.6 1.2 2.6 2.6 2.5 2.4 2.6 0.9 1.4 1.2 1.4 2.5 2.5 1.5
[1] 1y6a.a 1.7
0
0.8 1.6 1.9 2.5 2.5 2.3 1.9 2.1 2.1 1.7 1.9 2.2 2.2 2.3 2.0 2.3 1.9 2.0 2.1 2.2 1.5 2.1 2.1 2.0 2.0 2.2 1.7 1.9 1.6 1.9 2.1 2.1 1.1
[1] 1y6b.a 1.8 0.8
0
1.8 2.1 2.6 2.7 2.3 2.1 2.5 2.3 2.0 2.1 2.4 2.2 2.3 2.0 2.3 2.2 2.2 2.5 2.5 1.8 2.3 2.4 2.2 2.3 2.4 1.8 2.1 2.1 1.9 2.4 2.3 1.1
[1] 1ywn.a 1.4 1.6 1.8
0
0.8 2.0 2.0 1.6 1.4 1.6 1.6 1.4 1.1 1.8 1.6 1.6 1.6 1.7 1.4 1.5 1.7 1.7 1.1 1.4 1.6 1.4 1.4 1.7 1.6 1.8 2.2 1.6 1.6 1.8 1.7
[1] 2oh4.a 2.3 1.9 2.1 0.8
0
2.5 2.4 1.4 1.6 1.8 1.3 1.2 1.4 1.6 1.4 1.4 1.4 1.5 3.0 2.0 1.9 1.9 0.9 1.8 1.9 1.8 1.8 1.5 3.4 3.0 5.3 3.3 1.9 2.1 4.7
[1] 2p2i.a 2.9 2.5 2.6 2.0 2.5
0
1.3 1.2 2.3 2.2 1.1 1.9 2.4 1.4 1.1 1.1 1.4 1.0 2.7 2.2 2.4 2.2 1.8 2.1 2.2 2.0 2.1 1.2 3.3 3.0 3.5 3.3 2.0 2.0 2.5
[1] 2qu5.a 2.9 2.5 2.7 2.0 2.4 1.3
0
1.1 2.1 2.0 1.4 1.7 2.3 1.6 1.1 1.0 1.2 1.0 2.4 2.1 2.2 2.1 1.9 2.1 2.1 1.9 2.1 1.3 3.2 3.0 3.4 3.3 2.1 2.2 2.7
[1] 2qu6.b 2.7 2.3 2.3 1.6 1.4 1.2 1.1
0
1.4 1.1 1.0 1.3 2.0 1.1 0.8 0.6 1.1 0.8 1.4 1.5 1.5 1.2 1.4 1.1 1.3 1.0 1.1 1.2 2.7 2.5 3.0 2.7 1.2 1.4 1.8
[1] 2rl5.a 2.4 1.9 2.1 1.4 1.6 2.3 2.1 1.4
0
1.8 1.2 0.9 1.6 1.8 1.2 1.3 1.1 1.4 1.1 1.8 1.8 1.7 1.4 1.9 1.8 1.6 1.7 1.5 3.0 2.9 2.9 3.0 1.9 2.1 2.1
[1] 2xir.a 2.5 2.1 2.5 1.6 1.8 2.2 2.0 1.1 1.8
0
1.2 1.4 1.8 1.5 1.2 1.1 1.4 1.4 3.1 1.4 1.1 0.9 1.4 0.9 0.9 0.6 0.9 1.3 3.6 3.0 5.0 3.6 0.9 1.3 4.5
[1] 3b8q.a 2.5 2.1 2.3 1.6 1.3 1.1 1.4 1.0 1.2 1.2
0
1.2 1.9 0.9 0.7 0.9 1.0 0.9 1.3 1.3 1.4 1.3 1.5 1.1 1.3 1.0 1.0 1.1 2.6 2.2 2.9 2.5 0.9 1.2 1.6
[1] 3be2.a 2.2 1.7 2.0 1.4 1.2 1.9 1.7 1.3 0.9 1.4 1.2
0
1.7 1.5 1.1 1.3 1.1 1.4 0.7 1.3 1.6 1.6 1.4 1.4 1.6 1.2 1.3 1.5 2.5 2.5 2.7 2.5 1.4 1.6 1.6
[1] 3c7q.a 2.3 1.9 2.1 1.1 1.4 2.4 2.3 2.0 1.6 1.8 1.9 1.7
0
2.1 2.0 2.0 1.9 2.1 1.8 1.7 1.7 1.8 0.9 1.7 1.6 1.7 1.7 2.1 2.5 2.6 2.7 2.6 1.9 2.0 1.7
[1] 3cp9.b 2.6 2.2 2.4 1.8 1.6 1.4 1.6 1.1 1.8 1.5 0.9 1.5 2.1
0
0.8 0.7 1.1 0.9 2.0 1.6 1.8 1.6 1.6 1.4 1.6 1.3 1.4 0.9 3.3 3.0 3.4 3.3 1.2 1.4 2.4
[1] 3cpb.a 2.7 2.2 2.2 1.6 1.4 1.1 1.1 0.8 1.2 1.2 0.7 1.1 2.0 0.8
0
0.8 0.7 0.8 1.2 1.3 1.5 1.3 1.6 1.2 1.4 0.9 1.1 1.0 2.7 2.3 2.5 2.5 1.0 1.2 1.8
[1] 3cpc.b 2.7 2.3 2.3 1.6 1.4 1.1 1.0 0.6 1.3 1.1 0.9 1.3 2.0 0.7 0.8
0
0.9 0.8 1.3 1.3 1.5 1.2 1.4 1.0 1.3 0.9 1.0 0.9 3.0 2.8 2.8 3.0 1.0 1.3 1.7
[1] 3dtw.a 2.5 2.0 2.0 1.6 1.4 1.4 1.2 1.1 1.1 1.4 1.0 1.1 1.9 1.1 0.7 0.9
0
0.9 1.3 1.2 1.6 1.4 1.5 1.3 1.5 1.0 1.2 1.2 2.5 2.3 2.6 2.4 1.2 1.3 1.5
[1] 3efl.a 2.7 2.3 2.3 1.7 1.5 1.0 1.0 0.8 1.4 1.4 0.9 1.4 2.1 0.9 0.8 0.8 0.9
0
1.5 1.5 1.7 1.4 1.6 1.3 1.5 1.2 1.3 1.1 2.9 2.7 3.1 2.9 1.2 1.4 1.6
[1] 3ewh.a 2.4 1.9 2.2 1.4 3.0 2.7 2.4 1.4 1.1 3.1 1.3 0.7 1.8 2.0 1.2 1.3 1.3 1.5
0
3.0 3.1 3.2 1.6 3.1 3.2 3.0 3.1 1.6 3.2 3.0 3.9 3.1 3.1 3.2 3.2
[1] 3u6j.a 2.4 2.0 2.2 1.5 2.0 2.2 2.1 1.5 1.8 1.4 1.3 1.3 1.7 1.6 1.3 1.3 1.2 1.5 3.0
0
1.3 1.4 1.5 1.3 1.4 1.1 1.1 1.5 3.4 2.8 4.7 3.3 1.4 1.4 4.2
[1] 3vhe.a 2.5 2.1 2.5 1.7 1.9 2.4 2.2 1.5 1.8 1.1 1.4 1.6 1.7 1.8 1.5 1.5 1.6 1.7 3.1 1.3
0
0.9 2.4 1.1 0.9 0.8 1.1 1.6 3.6 3.1 5.0 3.5 1.2 1.5 4.5
[1] 3vhk.a 2.6 2.2 2.5 1.7 1.9 2.2 2.1 1.2 1.7 0.9 1.3 1.6 1.8 1.6 1.3 1.2 1.4 1.4 3.2 1.4 0.9
0
2.3 0.9 0.7 0.6 1.0 1.3 3.6 3.1 5.1 3.6 1.1 1.3 4.5
[1] 3vid.a 1.2 1.5 1.8 1.1 0.9 1.8 1.9 1.4 1.4 1.4 1.5 1.4 0.9 1.6 1.6 1.4 1.5 1.6 1.6 1.5 2.4 2.3
0
2.2 2.3 1.4 2.0 1.6 1.4 1.6 2.0 1.6 1.5 1.7 1.7
[1] 3vnt.a 2.6 2.1 2.3 1.4 1.8 2.1 2.1 1.1 1.9 0.9 1.1 1.4 1.7 1.4 1.2 1.0 1.3 1.3 3.1 1.3 1.1 0.9 2.2
0
0.7 0.8 0.9 1.2 3.6 3.1 5.1 3.6 0.9 1.2 4.4
[1] 3vo3.a 2.6 2.1 2.4 1.6 1.9 2.2 2.1 1.3 1.8 0.9 1.3 1.6 1.6 1.6 1.4 1.3 1.5 1.5 3.2 1.4 0.9 0.7 2.3 0.7
0
0.7 1.1 1.4 3.6 3.1 5.0 3.6 1.1 1.3 4.4
[1] 3wze.a 2.5 2.0 2.2 1.4 1.8 2.0 1.9 1.0 1.6 0.6 1.0 1.2 1.7 1.3 0.9 0.9 1.0 1.2 3.0 1.1 0.8 0.6 1.4 0.8 0.7
0
0.6 1.0 3.5 2.9 4.8 3.5 0.7 1.1 4.4
[1] 4ase.a 2.4 2.0 2.3 1.4 1.8 2.1 2.1 1.1 1.7 0.9 1.0 1.3 1.7 1.4 1.1 1.0 1.2 1.3 3.1 1.1 1.1 1.0 2.0 0.9 1.1 0.6
0
1.2 3.5 2.9 5.0 3.4 0.8 1.1 4.3
[1] 5ew3.a 2.6 2.2 2.4 1.7 1.5 1.2 1.3 1.2 1.5 1.3 1.1 1.5 2.1 0.9 1.0 0.9 1.2 1.1 1.6 1.5 1.6 1.3 1.6 1.2 1.4 1.0 1.2
0
2.9 2.6 3.1 2.9 1.0 1.2 1.7
[2] 2p2h.a 0.9 1.7 1.8 1.6 3.4 3.3 3.2 2.7 3.0 3.6 2.6 2.5 2.5 3.3 2.7 3.0 2.5 2.9 3.2 3.4 3.6 3.6 1.4 3.6 3.6 3.5 3.5 2.9
0
1.7 2.1 1.7 3.6 3.6 1.9
[2] 3b8r.b 1.4 1.9 2.1 1.8 3.0 3.0 3.0 2.5 2.9 3.0 2.2 2.5 2.6 3.0 2.3 2.8 2.3 2.7 3.0 2.8 3.1 3.1 1.6 3.1 3.1 2.9 2.9 2.6 1.7
0
2.2 1.0 2.9 3.0 1.7
[2] 3cjg.a 1.2 1.6 2.1 2.2 5.3 3.5 3.4 3.0 2.9 5.0 2.9 2.7 2.7 3.4 2.5 2.8 2.6 3.1 3.9 4.7 5.0 5.1 2.0 5.1 5.0 4.8 5.0 3.1 2.1 2.2
0
1.6 5.0 5.0 1.6
[2] 3wzd.a 1.4 1.9 1.9 1.6 3.3 3.3 3.3 2.7 3.0 3.6 2.5 2.5 2.6 3.3 2.5 3.0 2.4 2.9 3.1 3.3 3.5 3.6 1.6 3.6 3.6 3.5 3.4 2.9 1.7 1.0 1.6
0
3.5 3.5 2.1
[3] 4agc.a 2.5 2.1 2.4 1.6 1.9 2.0 2.1 1.2 1.9 0.9 0.9 1.4 1.9 1.2 1.0 1.0 1.2 1.2 3.1 1.4 1.2 1.1 1.5 0.9 1.1 0.7 0.8 1.0 3.6 2.9 5.0 3.5
0
0.8 4.3
[3] 4agd.a 2.5 2.1 2.3 1.8 2.1 2.0 2.2 1.4 2.1 1.3 1.2 1.6 2.0 1.4 1.2 1.3 1.3 1.4 3.2 1.4 1.5 1.3 1.7 1.2 1.3 1.1 1.1 1.2 3.6 3.0 5.0 3.5 0.8
0
4.3
[4] 3cjf.a 1.5 1.1 1.1 1.7 4.7 2.5 2.7 1.8 2.1 4.5 1.6 1.6 1.7 2.4 1.8 1.7 1.5 1.6 3.2 4.2 4.5 4.5 1.7 4.4 4.4 4.4 4.3 1.7 1.9 1.7 1.6 2.1 4.3 4.3
0
[Binding site full-atom RMSD matrix]







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