TYK2_MOUSE_877_1170

Non-receptor tyrosine-protein kinase TYK2 [Protein kinase superfamily. Tyr protein kinase family. JAK subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (TYK2_MOUSE):D: Protein kinase 2 (894,896:899,902:904,921,923,971:977,1020,1021,1023,1033,1034)894,896:899,902:904,921,923,971:977,1020,1021,1023,1033,1034

Full PDB list

4e1z,4e20

Contact map

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ligand
A1
R
8
9
4
L
8
9
6
G
8
9
7
E
8
9
8
G
8
9
9
G
9
0
2
K
9
0
3
V
9
0
4
A
9
2
1
K
9
2
3
M
9
7
1
E
9
7
2
Y
9
7
3
V
9
7
4
P
9
7
5
L
9
7
6
G
9
7
7
R
1
0
2
0
N
1
0
2
1
L
1
0
2
3
G
1
0
3
3
D
1
0
3
4
[1]4e1z.a 0mx 34 . . . . . . . . . . . . . . . . . . . . . .
[1]4e20.a 0my 27 . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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