TPMT_MOUSE_2_240

Thiopurine S-methyltransferase [Class I-like SAM-binding methyltransferase superfamily. TPMT family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (TPMT_MOUSE):147,148,151,152,190,191,221,22524,35,147,148,151,152,190,191,221,225
Cofactors (cF):sah

Full PDB list

2gb4,3bgd,3bgi (redundant pocketome entry)

Contact map

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ligand
A1 cF
W
2
4
F
3
5
R
1
4
7
G
1
4
8
V
1
5
1
A
1
5
2
P
1
9
0
P
1
9
1
R
2
2
1
W
2
2
5
[1]3bgd.b pm6 10 . . . . . . . . . . sah
[1]2gb4.a none . . . . . . . . . . sah

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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