TPA_HUMAN_302_562

Tissue-type plasminogen activator [Peptidase S1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (TPA_HUMAN):D: Peptidase S1 (357,358,401:403,484,507:513,531:537,544)357,358,401:403,484,507:513,531:537,544

Full PDB list

1a5h,1bda,1rtf,5brr

Contact map

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ligand
A1
H
3
5
7
C
3
5
8
D
4
0
1
T
4
0
2
Y
4
0
3
R
4
8
4
D
5
0
7
A
5
0
8
C
5
0
9
Q
5
1
0
G
5
1
1
D
5
1
2
S
5
1
3
I
5
3
1
S
5
3
2
W
5
3
3
G
5
3
4
L
5
3
5
G
5
3
6
C
5
3
7
G
5
4
4
[1]1a5h.a bba 28 . . . . . . . . . . . . . . . . . . . . .
[1]1bda.a 2z0 41 * . . . . . . . . . . . * . . . . . . . .
[1]1rtf.b ben 9 . . . . . . . . . . . . . . . . . . . . .
[1]5brr.e VSAR 29 . . . . . . . . . . . . A . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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