TOPK_HUMAN_20_320

Lymphokine-activated killer T-cell-originated protein kinase [Protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (TOPK_HUMAN):D: Protein kinase (78,101,103,116,117)78,101,103,116,117
 • A2 (TOPK_HUMAN):D: Protein kinase (78,101,103)78,101,103

Full PDB list

5j0a

Contact map

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ligand
A1 A2
Y
7
8
R
1
0
1
F
1
0
3
E
1
1
6
Y
1
1
7
Y
7
8
R
1
0
1
F
1
0
3
[1]5j0a.a hc4 12 . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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