TIE2_HUMAN_806_1124

Angiopoietin-1 receptor [Protein kinase superfamily. Tyr protein kinase family. Tie subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (TIE2_HUMAN):D: Protein kinase (830:833,838,853:855,872,875,876,879,886,900,902:905,908,955,960,962,968,969,971,980:983,987)830:833,838,853:855,872,875,876,879,886,900,902:905,908,955,960,962,968,969,971,980:983,987

Full PDB list

1fvr,2oo8,2osc,2p4i,2wqb,3l8p,4x3j

Contact map

[download in TSV format]
   
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ligand
A1
I
8
3
0
G
8
3
1
E
8
3
2
G
8
3
3
V
8
3
8
A
8
5
3
I
8
5
4
K
8
5
5
E
8
7
2
V
8
7
5
L
8
7
6
L
8
7
9
I
8
8
6
L
9
0
0
I
9
0
2
E
9
0
3
Y
9
0
4
A
9
0
5
G
9
0
8
L
9
5
5
F
9
6
0
H
9
6
2
R
9
6
8
N
9
6
9
L
9
7
1
I
9
8
0
A
9
8
1
D
9
8
2
F
9
8
3
R
9
8
7
[1]3l8p.a 0ce 34 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4x3j.a 3wr 33 - - - - . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]2osc.a muh 33 - - - - . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]2wqb.a qq1 28 . . . . . . . . - . . . . . . . . . . . . . . . . . . . . .
[1]2oo8.x raj 39 - - - - . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]2p4i.a mr9 41 - - - - . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]1fvr.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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