TGFR2_HUMAN_236_549

TGF-beta receptor type-2 [Protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (TGFR2_HUMAN):D: Protein kinase (250,251,253:256,258,275,277,305,325:329,331,332,381,383,384,386,396,397)250,251,253:256,258,275,277,305,325:329,331,332,381,383,384,386,396,397

Full PDB list

5e8v,5e8y,5e91,5e92

Contact map

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ligand
A1
V
2
5
0
G
2
5
1
G
2
5
3
R
2
5
4
F
2
5
5
A
2
5
6
V
2
5
8
A
2
7
5
K
2
7
7
L
3
0
5
T
3
2
5
A
3
2
6
F
3
2
7
H
3
2
8
A
3
2
9
G
3
3
1
N
3
3
2
K
3
8
1
S
3
8
3
N
3
8
4
L
3
8
6
C
3
9
6
D
3
9
7
[1]5e91.a 5l4 31 . . . . . . . . . . . . . . . . . . . . . . .
[1]5e8y.a stu 35 . . . . . . . . . . . . . . . . . . . . . . .
[1]5e8v.a none . . . . . . . . . . . . . . . . . . . . . . .
[1]5e92.a anp,mg,mg 33 . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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