SYG_HUMAN_114_739

Glycine--tRNA ligase [Class-II aminoacyl-tRNA synthetase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (SYG_HUMAN):R: Substrate binding (346,348,350)
R: Substrate binding (576,578,580)
194,198,200,213,247,280,298,299,331,333,340:343,432,435,436,440,457:459,464,583
194,198,200,213,247,280,298,299,331,333,340:343,346,348,350,432,435,436,440,457:459,464,576,578,580,583

Full PDB list

2pme,2pmf,2q5h,2q5i,2zt5,2zt6,2zt7,2zt8,2zxf,4kqe,4kr2,4kr3,4qei,5e6m (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1
H
1
9
4
F
1
9
8
D
2
0
0
R
2
1
3
D
2
4
7
L
2
8
0
P
2
9
8
E
2
9
9
R
3
3
1
E
3
3
3
L
3
4
0
I
3
4
1
R
3
4
2
V
3
4
3
F
3
4
6
M
3
4
8
E
3
5
0
H
4
3
2
N
4
3
5
E
4
3
6
Y
4
4
0
E
4
5
7
I
4
5
8
V
4
5
9
R
4
6
4
E
5
7
6
S
5
7
8
G
5
8
0
R
5
8
3
[1]2zt8.a drv 27 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]5e6m.a CA,gap 69 . . . - - . . . . . . . . . . . . . . . - . . . . . . . .
[1]2zt6.a apc 31 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]4kr2.a amp 23 . - - - - . . . . . . . . . . . . . - - - . . . . . . . .
[3]2pmf.a none . . . . . . . . . . . . . . . . . . . - - . . . . . . R .
[1]2zt5.a b4p 53 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2zt7.a atp,G 36 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]4kqe.a none . . . . . . . . . . . . . . . . . . . . - . . . . . . . .
[2]4kr3.a anp,G 36 . . - - - . . . . . . . . . . . . . . - - . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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