SYFA_THET8_85_350

Phenylalanine--tRNA ligase alpha subunit [Class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (SYFA_THET8):148,149,178,180,183,204,206,212,213,216,218,220,258,260,261,280:284,314:318,321,332148,149,178,180,183,204,206,212,213,216,218,220,258,260,261,280:284,314:318,321,332
Metals (Me):Mg/Mn

Full PDB list

1b70,1b7y,1eiy,1jjc,1pys,2akw,2aly,2amc,2iy5,3hfz,3teh,4tva (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1 Me
M
1
4
8
W
1
4
9
H
1
7
8
S
1
8
0
Q
1
8
3
R
2
0
4
E
2
0
6
H
2
1
2
E
2
1
3
F
2
1
6
Q
2
1
8
E
2
2
0
F
2
5
8
F
2
6
0
V
2
6
1
L
2
8
0
G
2
8
1
G
2
8
2
A
2
8
3
G
2
8
4
A
3
1
4
F
3
1
5
G
3
1
6
L
3
1
7
G
3
1
8
R
3
2
1
I
3
3
2
[1]2aly.a ysa 35 . . . . . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]1jjc.a fa5 34 . . . . . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]1b7y.a fya 33 . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]1b70.a F 12 . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]1eiy.a A 22 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1pys.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]2akw.a 200 13 . . . . . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]2amc.a Y 13 . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]3hfz.a mty 13 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3teh.a dah 14 . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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