S1PR1_HUMAN_1_327_TM

Sphingosine 1-phosphate receptor 1 [G-protein coupled receptor 1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (S1PR1_HUMAN):R: Sphingosine 1-phosphate binding (120,121)
R: Sphingosine 1-phosphate binding (269)
29,34,101,124,125,128,194,206,272,276,294,297,301
29,34,101,120,121,124,125,128,194,206,269,272,276,294,297,301

Full PDB list

3v2w,3v2y (redundant pocketome entry)

Contact map

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ligand
A1
Y
2
9
K
3
4
N
1
0
1
R
1
2
0
E
1
2
1
M
1
2
4
F
1
2
5
L
1
2
8
V
1
9
4
C
2
0
6
W
2
6
9
L
2
7
2
L
2
7
6
E
2
9
4
L
2
9
7
V
3
0
1
[1]3v2y.a ml5 23 . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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