ROS1_HUMAN_1932_2232

Proto-oncogene tyrosine-protein kinase ROS [Protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ROS1_HUMAN):D: Protein kinase (1951,1959,1978,1980,2010,2026:2030,2032,2033,2083,2084,2086,2101,2102)1951,1959,1978,1980,2010,2026:2030,2032,2033,2083,2084,2086,2101,2102

Full PDB list

3zbf,4uxl

Contact map

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ligand
A1
L
1
9
5
1
V
1
9
5
9
A
1
9
7
8
K
1
9
8
0
L
2
0
1
0
L
2
0
2
6
E
2
0
2
7
L
2
0
2
8
M
2
0
2
9
E
2
0
3
0
G
2
0
3
2
D
2
0
3
3
R
2
0
8
3
N
2
0
8
4
L
2
0
8
6
G
2
1
0
1
D
2
1
0
2
[1]4uxl.a 5p8 30 . . . . . . . . . . . . . . . . .
[1]3zbf.a vgh 30 . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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