RIPK2_HUMAN_2_311

Receptor-interacting serine/threonine-protein kinase 2 [Protein kinase superfamily. TKL Ser/Thr protein kinase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (RIPK2_HUMAN):D: Protein kinase (22:30,32,45:47,66,69,70,73,78,79,81,93,95:98,101,102,105,135,142:144,150,151,153,162:165,171)22:30,32,45:47,66,69,70,73,78,79,81,93,95:98,101,102,105,135,142:144,150,151,153,162:165,171

Full PDB list

4c8b,5ar2,5ar3,5ar4,5ar5,5ar7,5ar8,5j79,5j7b

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1
R
2
2
Y
2
3
L
2
4
S
2
5
R
2
6
G
2
7
A
2
8
S
2
9
G
3
0
V
3
2
A
4
5
V
4
6
K
4
7
E
6
6
I
6
9
L
7
0
A
7
3
I
7
8
L
7
9
I
8
1
I
9
3
T
9
5
E
9
6
Y
9
7
M
9
8
G
1
0
1
S
1
0
2
E
1
0
5
L
1
3
5
L
1
4
2
L
1
4
3
H
1
4
4
Q
1
5
0
N
1
5
1
L
1
5
3
I
1
6
2
A
1
6
3
D
1
6
4
F
1
6
5
R
1
7
1
[1]5j7b.b 6gd 28 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]5ar5.a iq7 32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]5ar7.a sr8 26 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]5j79.a 6ge 23 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]5ar4.a sb2 27 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]4c8b.a 0li 39 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]5ar8.a xyw 46 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]5ar3.a acp,mg 32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]5ar2.a none . . . . - - - - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
Similar entries
Feedback