RARA_HUMAN_173_420

Retinoic acid receptor alpha [Nuclear hormone receptor family. NR1 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (RARA_HUMAN):R: Ligand-binding (225,228,229,231:233,235,236,266,269,270,272,273,276,286,287,301,302,305,391,394,395,398,406,407,410,414)199,225,228,229,231:233,235,236,266,269,270,272,273,276,286,287,301,302,305,391,394,395,398,406,407,410,414

Full PDB list

1dkf,3a9e,3kmr,3kmz,4dqm,5k13

Contact map

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ligand
A1
F
1
9
9
W
2
2
5
F
2
2
8
S
2
2
9
L
2
3
1
S
2
3
2
T
2
3
3
C
2
3
5
I
2
3
6
L
2
6
6
L
2
6
9
I
2
7
0
R
2
7
2
I
2
7
3
R
2
7
6
F
2
8
6
S
2
8
7
G
3
0
1
F
3
0
2
L
3
0
5
G
3
9
1
R
3
9
4
V
3
9
5
L
3
9
8
M
4
0
6
P
4
0
7
I
4
1
0
L
4
1
4
[1]5k13.a 6q7 34 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3a9e.b rea 22 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1dkf.b bms 34 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3kmr.a eqn 26 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3kmz.b eqo,L 39 . . . . . . . . . . . . . . . . . . . . . . . . - - - -
[1]4dqm.a luf 28 . . . . . . . * . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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