PYLS_METMA_185_454

Pyrrolysine--tRNA ligase [Class-II aminoacyl-tRNA synthetase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (PYLS_METMA):278,284,287,288,299,300,330,381,383,384278,284,287,288,299,300,330,381,383,384
Cofactors (cF):anp/yly
Metals (Me):Mg

Full PDB list

2e3c,2q7e,2q7g,2q7h,2zce,2zim,2zin,2zio,3qtc,3vqv,3vqw,3vqx,3vqy,4bw9,4bwa,4ch3,4ch4,4ch5,4ch6,4cs2,4cs3,4cs4,4q6g,4tqd,4tqf,4zib,5k1p,5k1x (redundant pocketome entry)

Contact map

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ligand
A1 cF Me
I
2
7
8
L
2
8
4
Q
2
8
7
I
2
8
8
P
2
9
9
M
3
0
0
R
3
3
0
C
3
8
1
V
3
8
3
Y
3
8
4
[1]4cs4.a axz 17 . . . . . . . . . F anp Mg
[1]2q7h.a none . . . . . . . . . . yly
[1]3vqw.a none . . . . . * . - - - anp Mg
[1]4cs2.a none . . . . . . . . . F
[2]4q6g.a none . . . . . . . . . . anp

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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