PRGR_HUMAN_677_933

Progesterone receptor [Nuclear hormone receptor family. NR3 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (PRGR_HUMAN):R: Steroid-binding (715,718,719,721:723,725,726,755,756,759,760,763,766,778,794,797,798,801,887,890,891,894,903,905,909,912,913)715,718,719,721:723,725,726,755,756,759,760,763,766,778,794,797,798,801,887,890,891,894,903,905,909,912,913

Full PDB list

1a28,1e3k,1sqn,1sr7,1zuc,2ovh,2ovm,2w8y,3d90,3g8o,3hq5,3kba,3zr7,3zra,3zrb,4a2j,4apu,4oar (redundant pocketome entry)

Contact map

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ligand
A1
L
7
1
5
L
7
1
8
N
7
1
9
L
7
2
1
G
7
2
2
E
7
2
3
Q
7
2
5
L
7
2
6
W
7
5
5
M
7
5
6
M
7
5
9
V
7
6
0
L
7
6
3
R
7
6
6
F
7
7
8
F
7
9
4
L
7
9
7
C
7
9
8
M
8
0
1
L
8
8
7
Y
8
9
0
C
8
9
1
T
8
9
4
V
9
0
3
F
9
0
5
M
9
0
9
V
9
1
2
I
9
1
3
[1]3hq5.a gkk 27 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3zrb.b orc 26 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3zra.b orb 27 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3kba.a wow 27 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4oar.a 2s0 35 . . . . . . . . . . . . . . . . . . . . . . . - - . . .
[1]3g8o.a 30x 25 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1sr7.a mof 35 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4apu.b a2k 38 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3zr7.a or8 26 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3d90.b nog 23 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2w8y.a 486 32 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2w8y.b ndr 22 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1zuc.b t98 21 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1a28.b str 23 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1e3k.a r18 21 . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4a2j.b as0 33 . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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