PLK4_HUMAN_1_277_ATPsite

Serine/threonine-protein kinase PLK4 [Protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (PLK4_HUMAN):D: Protein kinase (18:21,23,26,28,39,41,73,89:96,99,140,142,143,153,154,160)18:21,23,26,28,39,41,73,89:96,99,140,142,143,153,154,160

Full PDB list

3cok,4jxf,4yur

Contact map

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ligand
A1
L
1
8
G
1
9
K
2
0
G
2
1
F
2
3
V
2
6
R
2
8
A
3
9
K
4
1
L
7
3
L
8
9
E
9
0
M
9
1
C
9
2
H
9
3
N
9
4
G
9
5
E
9
6
R
9
9
S
1
4
0
L
1
4
2
L
1
4
3
A
1
5
3
D
1
5
4
Q
1
6
0
[1]3cok.a anp 27 . . . . . . . . . . . . . . . . . . . . . . . . .
[2]4jxf.a 631 35 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4yur.a 4j7 43 . . . . . . . . . . . . . . . . . . . . . . . . -

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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