PGES2_MACFA_88_377

Prostaglandin E synthase 2 [GST superfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (PGES2_MACFA):D: Glutaredoxin (107,109:112,134,137)
D: GST C-terminal (263,264,293,343,347)
243,244,246,247,250,251,260
107,109:112,134,137,243,244,246,247,250,251,260,263,264,293,343,347
Cofactors (cF):gsh
Metals (Me):Fe

Full PDB list

1z9h,2pbj

Contact map

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ligand
A1 cF Me
Y
1
0
7
T
1
0
9
C
1
1
0
P
1
1
1
F
1
1
2
P
1
3
4
R
1
3
7
V
2
4
3
H
2
4
4
I
2
4
6
S
2
4
7
V
2
5
0
Y
2
5
1
S
2
6
0
Y
2
6
3
I
2
6
4
L
2
9
3
V
3
4
3
L
3
4
7
[1]1z9h.a imn 25 . . . . . . . . . . . . . . . . . . .
[1]2pbj.a hem 42 . . . . . . . . . . . . . . . . . . . gsh Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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