P2Y12_HUMAN_1_342

P2Y purinoceptor 12 [G-protein coupled receptor 1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (P2Y12_HUMAN):93,97,101,102,105,106,109,155,156,159,173:175,179,187,190,191,194,252,256,259,263,276,28093,97,101,102,105,106,109,155,156,159,173:175,179,187,190,191,194,252,256,259,263,276,280
Cofactors (cF):olc

Full PDB list

4ntj,4pxz,4py0

Contact map

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ligand
A1 cF
R
9
3
C
9
7
S
1
0
1
V
1
0
2
Y
1
0
5
F
1
0
6
Y
1
0
9
L
1
5
5
S
1
5
6
N
1
5
9
K
1
7
3
K
1
7
4
C
1
7
5
K
1
7
9
H
1
8
7
V
1
9
0
N
1
9
1
C
1
9
4
F
2
5
2
R
2
5
6
Y
2
5
9
Q
2
6
3
L
2
7
6
K
2
8
0
[2]4ntj.a azj 33 . . . . . . . . . . - - - . . . . . . . . . . .
[1]4pxz.a 6ad 29 . . . . . . . . . . . . . . . . . . . . . . . . olc
[1]4py0.a 6at 33 . . . . . . . . . . . . . . . . . . . . . . . . olc

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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