OPSD_HUMAN_1_348_allosteric

Rhodopsin [G-protein coupled receptor 1 family. Opsin subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (OPSD_HUMAN):R: Retinal chromophore binding (208,212)
30,31,33,266,267,270,271,273,274,283:287
30,31,33,208,212,266,267,270,271,273,274,283:287

Full PDB list

1f88,1gzm,1hzx,1l9h,1u19,2g87,2hpy,2j4y,2ped,2x72,3c9l,3c9m,3cap,3dqb,3oax,3pqr,3pxo,4a4m,4bey,4bez,4j4q,4pxf,4x1h,4zwj,5dys,5en0 (redundant pocketome entry)

Contact map

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ligand
A1
Y
3
0
L
3
1
E
3
3
F
2
0
8
F
2
1
2
V
2
6
6
P
2
6
7
S
2
7
0
V
2
7
1
F
2
7
3
Y
2
7
4
F
2
8
3
G
2
8
4
P
2
8
5
I
2
8
6
F
2
8
7
[1]3oax.a htg,id3 33 . . . . . L . G . . . . . . . .
[1]1hzx.b bng 21 . . . . . L . G . . . . . . . .
[1]1gzm.a lda 16 . . . . . L . G . . . . . . . .
[1]1gzm.b lda,lda 32 . . . . . L . G . . . . . . . .
[1]1l9h.a bng,bng 42 . . . . . L . G . . . . . . . .
[1]1u19.a htg 19 . . . . . L . G . . . . . . . .
[2]4zwj.a none . . . . . . . . . . . . . . . .
[2]3pxo.a none . . . . . L . G . . . . . . . .
[2]5dys.a none . . . . . L . G . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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