NTRK2_HUMAN_526_822

BDNF/NT-3 growth factors receptor [Protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (NTRK2_HUMAN):D: Protein kinase (544,549,552,570,572,588,592,595,600,601,617:621,623,672,674,681,683,692:695,697)544,549,552,570,572,588,592,595,600,601,617:621,623,672,674,681,683,692:695,697

Full PDB list

4asz,4at3,4at4,4at5

Contact map

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ligand
A1
L
5
4
4
F
5
4
9
V
5
5
2
A
5
7
0
K
5
7
2
E
5
8
8
L
5
9
2
L
5
9
5
I
6
0
0
V
6
0
1
F
6
1
7
E
6
1
8
Y
6
1
9
M
6
2
0
K
6
2
1
G
6
2
3
F
6
7
2
H
6
7
4
N
6
8
1
L
6
8
3
I
6
9
2
G
6
9
3
D
6
9
4
F
6
9
5
M
6
9
7
[1]4at5.a muj 27 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4at4.a t6e 31 . . . . . . . . . . . . . . . . . . . . . . . . .
[2]4at3.a lti 24 . . . . . . . . . . . . . . . . . . . . . . . . .
[2]4asz.a none . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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