NR5A2_HUMAN_295_540

Nuclear receptor subfamily 5 group A member 2 [Nuclear hormone receptor family. NR5 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (NR5A2_HUMAN):R: Ligand-binding (342,345,346,348,349,382,383,386,387,390)
R: Lipid binding (419:424)
341,403,405,411,415,416,427,428,431,513,514,516,517,519,520,532
341,342,345,346,348,349,382,383,386,387,390,403,405,411,415,416,419:424,427,428,431,513,514,516,517,519,520,532

Full PDB list

1yok,1yuc,1zdu,3plz,3tx7,4dor,4dos,4is8,4oni,4pld,4ple,4rwv,5l11,5syz (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1
T
3
4
1
F
3
4
2
M
3
4
5
C
3
4
6
M
3
4
8
A
3
4
9
W
3
8
2
S
3
8
3
L
3
8
6
I
3
8
7
H
3
9
0
I
4
0
3
L
4
0
5
V
4
1
1
I
4
1
5
I
4
1
6
Q
4
1
9
A
4
2
0
G
4
2
1
A
4
2
2
T
4
2
3
L
4
2
4
L
4
2
7
M
4
2
8
A
4
3
1
A
5
1
3
E
5
1
4
Y
5
1
6
L
5
1
7
Y
5
1
9
K
5
2
0
L
5
3
2
[2]3plz.b 470 29 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]5l11.a rjw 29 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[3]4pld.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]5syz.a 71w 29 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4ple.a eph 47 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1zdu.a p3a 58 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4dos.a plc 41 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[4]4is8.a none . . . . . . . . . . . . . . . . H T E V A F . . . . . . . . . .
[1]4oni.b p6l 51 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4rwv.a piz 67 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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