NR1I2_HUMAN_130_434

Nuclear receptor subfamily 1 group I member 2 [Nuclear hormone receptor family. NR1 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (NR1I2_HUMAN):R: Ligand-binding (205,206,209:211,240,242:244,246,247,251,281,284,285,288,299,301,306,308,323,324,327,407,410,411,414,420,425,429)205,206,209:211,240,242:244,246,247,251,281,284,285,288,299,301,306,308,323,324,327,407,410,411,414,420,425,429

Full PDB list

1ilg,1ilh,1m13,1nrl,1skx,2o9i,2qnv,3ctb,3hvl,4j5w,4j5x,4ny9,4s0s,4s0t,4x1f,4x1g,4xao,4xhd,5a86 (redundant pocketome entry); 3r8d (unprocessed)

Contact map

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ligand
A1
D
2
0
5
L
2
0
6
L
2
0
9
K
2
1
0
V
2
1
1
L
2
4
0
H
2
4
2
M
2
4
3
A
2
4
4
M
2
4
6
S
2
4
7
F
2
5
1
F
2
8
1
C
2
8
4
Q
2
8
5
F
2
8
8
W
2
9
9
C
3
0
1
Y
3
0
6
L
3
0
8
M
3
2
3
L
3
2
4
H
3
2
7
H
4
0
7
R
4
1
0
L
4
1
1
I
4
1
4
F
4
2
0
M
4
2
5
F
4
2
9
[1]4ny9.a 2q4 30 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2qnv.a cdz 29 - - . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]5a86.a d7e 28 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1m13.a hyf 39 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4x1f.a 3wf 22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4x1g.a 3wf,3wg 41 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2o9i.b 444 31 . . . . . . . . . . . . . S . . . . . . . . . . . . . . . .
[1]4xhd.a 40u 29 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1nrl.a srl 33 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1skx.a rfp 51 - - - . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4j5w.b none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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