MP2K7_HUMAN_102_417

Dual specificity mitogen-activated protein kinase kinase 7 [Protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (MP2K7_HUMAN):D: Protein kinase (126,129,130,134,147,149,196,197,199,202,205,247,250)126,129,130,134,147,149,196,197,199,202,205,247,250

Full PDB list

2dyl,3wzu,5b2k,5b2l,5b2m (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1
M
1
2
6
G
1
2
9
T
1
3
0
V
1
3
4
A
1
4
7
K
1
4
9
M
1
9
6
E
1
9
7
M
1
9
9
C
2
0
2
K
2
0
5
S
2
4
7
L
2
5
0
[1]3wzu.a 1fm 26 . . . . . . . . . . . . .
[2]5b2k.a none . . - . . . . . . . . . .
[1]5b2l.a none . . . . . . . . . S . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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