MP2K6_HUMAN_43_333

Dual specificity mitogen-activated protein kinase kinase 6 [Protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (MP2K6_HUMAN):D: Protein kinase (59,60,64,67,80,82,129:135,137,138,179,181,183,184,186,196,197,201,210)59,60,64,67,80,82,129:135,137,138,179,181,183,184,186,196,197,201,210

Full PDB list

3enm,3fme,3vn9

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1
L
5
9
G
6
0
Y
6
4
V
6
7
A
8
0
K
8
2
M
1
2
9
E
1
3
0
L
1
3
1
M
1
3
2
D
1
3
3
T
1
3
4
S
1
3
5
D
1
3
7
K
1
3
8
D
1
7
9
K
1
8
1
S
1
8
3
N
1
8
4
L
1
8
6
C
1
9
6
D
1
9
7
S
2
0
1
K
2
1
0
[1]3fme.a stu 35 . . . . . . . . . . . . . . . . . . . . . . - -
[2]3enm.b none . . . . . . * . . * . . . . . . . . . . . . . -
[1]3vn9.a ank,mg 32 . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
Similar entries
Feedback