MLKL_HUMAN_185_471

Mixed lineage kinase domain-like protein [Protein kinase superfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (MLKL_HUMAN):D: Protein kinase (209:212,215,217,228,230,250,254,263,283:286,289,293,320,335,336,338,348,349)209:212,215,217,228,230,250,254,263,283:286,289,293,320,335,336,338,348,349

Full PDB list

4m67,4mwi,5knj,5ko1 (redundant pocketome entry)

Contact map

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ligand
A1
L
2
0
9
R
2
1
0
E
2
1
1
N
2
1
2
S
2
1
5
L
2
1
7
A
2
2
8
K
2
3
0
E
2
5
0
M
2
5
4
L
2
6
3
M
2
8
3
E
2
8
4
Y
2
8
5
C
2
8
6
G
2
8
9
E
2
9
3
L
3
2
0
S
3
3
5
N
3
3
6
L
3
3
8
A
3
4
8
G
3
4
9
[1]5ko1.a 6uy 27 . . . . . . . . . . . . . . . . . . . . . . .
[3]5knj.b 6ux 40 . . . . . . . . . . . . . . . . . . . . . . .
[2]4mwi.a none . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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