MKNK2_HUMAN_70_385

MAP kinase-interacting serine/threonine-protein kinase 2 [Protein kinase superfamily. CAMK Ser/Thr protein kinase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (MKNK2_HUMAN):D: Protein kinase (90:92,98,111,113,143,159:162,165,209,212,225)
R: Staurosporine binding (160:162)
90:92,98,111,113,143,159:162,165,209,212,225

Full PDB list

2ac3,2ac5,2hw7 (redundant pocketome entry)

Contact map

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ligand
A1
L
9
0
G
9
1
E
9
2
V
9
8
A
1
1
1
K
1
1
3
L
1
4
3
F
1
5
9
E
1
6
0
K
1
6
1
M
1
6
2
G
1
6
5
E
2
0
9
L
2
1
2
C
2
2
5
[1]2hw7.a stu 35 . . . . . . . . . . . . . . .
[1]2ac3.a none . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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