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MK12_HUMAN_1_367_ATPsite

Mitogen-activated protein kinase 12 [Protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily]

Composition of the binding site

Protein chains monomer [domain annotation]
A1 (MK12_HUMAN):D: Protein kinase (41, 54, 56, 87, 109:112, 115, 155, 157, 158, 170, 171)41, 54, 56, 87, 109:112, 115, 155, 157, 158, 170, 171
Metals (Me):Mg

Full PDB list

1cm8

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 Me
V
4
1
A
5
4
K
5
6
I
8
7
M
1
0
9
P
1
1
0
F
1
1
1
M
1
1
2
D
1
1
5
K
1
5
5
G
1
5
7
N
1
5
8
L
1
7
0
D
1
7
1
[1]1cm8.a anp31 . . . . . . . . . . . . . . Mg

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1 Me
V
4
1
A
5
4
K
5
6
I
8
7
M
1
0
9
P
1
1
0
F
1
1
1
M
1
1
2
D
1
1
5
K
1
5
5
G
1
5
7
N
1
5
8
L
1
7
0
D
1
7
1
[1]1cm8.a . . . . . . . . . . . . . . Mg

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)







[show 3D visualization]

[ENTRY 2D visualization]

L C X E | Background Color: | Anaglyph Stereo:

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