MK03_HUMAN_13_379

Mitogen-activated protein kinase 3 [Protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (MK03_HUMAN):D: Protein kinase (48,50:53,56,69,71,73,81,84,85,88,122:127,131,170,173,183,184,186)48,50:53,56,69,71,73,81,84,85,88,122:127,131,170,173,183,184,186
Metals (Me):Na

Full PDB list

2zoq,4qtb

Contact map

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ligand
A1 Me
I
4
8
E
5
0
G
5
1
A
5
2
Y
5
3
V
5
6
A
6
9
K
7
1
I
7
3
Y
8
1
R
8
4
T
8
5
E
8
8
Q
1
2
2
D
1
2
3
L
1
2
4
M
1
2
5
E
1
2
6
T
1
2
7
K
1
3
1
S
1
7
0
L
1
7
3
C
1
8
3
D
1
8
4
G
1
8
6
[1]4qtb.a 38z 44 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2zoq.a 5id 20 . . . . . . . . . . . . . . . . . . . . . . . . . Na

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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