MCR_HUMAN_723_984

Mineralocorticoid receptor [Nuclear hormone receptor family. NR3 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (MCR_HUMAN):R: Steroid-binding (766,769,770,772,773,776,806,807,810,811,814,817,829,840,845,848,849,852,938,941,942,945,954,956,960)766,769,770,772,773,776,806,807,810,811,814,817,829,840,845,848,849,852,938,941,942,945,954,956,960

Full PDB list

1y9r,1ya3,2a3i,2aa2,2aa5,2aa6,2aa7,2aax,2ab2,2abi,2oax,3vhu,3vhv,3wff,3wfg,4pf3,4uda,4udb,5hcv (redundant pocketome entry)

Contact map

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ligand
A1
L
7
6
6
L
7
6
9
N
7
7
0
L
7
7
2
A
7
7
3
Q
7
7
6
W
8
0
6
M
8
0
7
S
8
1
0
S
8
1
1
L
8
1
4
R
8
1
7
F
8
2
9
M
8
4
0
M
8
4
5
L
8
4
8
C
8
4
9
M
8
5
2
L
9
3
8
F
9
4
1
C
9
4
2
T
9
4
5
V
9
5
4
F
9
5
6
L
9
6
0
[1]5hcv.a 60r 28 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2aa2.a as4 26 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4pf3.a hfn 30 . . . . . . . . L . . . . . . . . . . . . . . . .
[1]3vhv.a ld1 26 . . . . . . . . L . . . . . . . . . . . . . . . .
[1]3wff.a wff 25 . . . . . . . . L . . . . . . . . . . . . . . . .
[1]3wfg.a wfg 25 . . . . . . . . L . . . . . . . . . . . . . . . .
[1]4udb.a cv7 34 . . . . . . . . L . . . . . . . . . . . . . . . .
[1]2ab2.a snl 29 . . . . . . . . L . . . . . . . . . . . . . . . .
[1]2a3i.a c0r 25 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4uda.a dex 28 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2aax.a pdn 26 . . . . . . . . L . . . . . . . . . . . . . . . .
[1]1y9r.a 1ca 24 . . . . . . . . L . . . . . . . . . . . . . . . .
[1]2aa5.a str 23 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2abi.c 1ca 24 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2aa6.a str 23 . . . . . . . . L . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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