MARK2_HUMAN_40_364

Serine/threonine-protein kinase MARK2 [Protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (MARK2_HUMAN):D: Protein kinase (59:62,67,80,82,129:133,135,179,182,193,197)59:62,67,80,82,129:133,135,179,182,193,197

Full PDB list

1y8g,1zmu,1zmv,1zmw,2r0i,2wzj,3iec,5eak (redundant pocketome entry)

Contact map

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ligand
A1
I
5
9
G
6
0
K
6
1
G
6
2
V
6
7
A
8
0
K
8
2
M
1
2
9
E
1
3
0
Y
1
3
1
A
1
3
2
S
1
3
3
G
1
3
5
E
1
7
9
L
1
8
2
D
1
9
3
S
1
9
7
[1]5eak.a 24r 30 . . . . . . . . . . . . . . . . .
[1]1y8g.a none . . . . . . . * . . . . . . . - -
[1]2wzj.a none . - - - . . R . . . . . . . . . .
[1]3iec.c none . . - - . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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