M3K14_HUMAN_321_678

Mitogen-activated protein kinase kinase kinase 14 [Protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (M3K14_HUMAN):D: Protein kinase (406:412,414,427,429,440,444,453,467,469:472,475,476,479,515,519,520,522,533:535,537)
R: Interaction with ZFP91 (406:412,414,427,429,440,444,453,467,469:472,475,476,479,515,519,520,522,533:535,537)
406:412,414,427,429,440,444,453,467,469:472,475,476,479,515,519,520,522,533:535,537

Full PDB list

4dn5,4g3d,4idt,4idv

Contact map

[download in TSV format]
   
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ligand
A1
L
4
0
6
G
4
0
7
R
4
0
8
G
4
0
9
S
4
1
0
F
4
1
1
G
4
1
2
V
4
1
4
A
4
2
7
K
4
2
9
E
4
4
0
C
4
4
4
V
4
5
3
I
4
6
7
M
4
6
9
E
4
7
0
L
4
7
1
L
4
7
2
G
4
7
5
S
4
7
6
Q
4
7
9
D
5
1
5
D
5
1
9
N
5
2
0
L
5
2
2
C
5
3
3
D
5
3
4
F
5
3
5
H
5
3
7
[1]4idv.b 13v 27 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4idt.a t28 20 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4dn5.a ags,mg 32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4g3d.a mg 1 - . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4g3d.b none - . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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