LYN_HUMAN_235_512

Tyrosine-protein kinase Lyn [Protein kinase superfamily. Tyr protein kinase family. SRC subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (LYN_HUMAN):D: Protein kinase (253,261,273,275,290,294,303,317,319:326,371,374,384,385)253,261,273,275,290,294,303,317,319:326,371,374,384,385

Full PDB list

2zv7,2zv8,2zv9,2zva,3a4o

Contact map

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ligand
A1
L
2
5
3
V
2
6
1
A
2
7
3
K
2
7
5
E
2
9
0
M
2
9
4
V
3
0
3
I
3
1
7
T
3
1
9
E
3
2
0
Y
3
2
1
M
3
2
2
A
3
2
3
K
3
2
4
G
3
2
5
S
3
2
6
A
3
7
1
L
3
7
4
A
3
8
4
D
3
8
5
[1]2zva.a 1n1 33 . . . . . . . . . . F . . . . . . . . .
[1]2zv9.a pp2 21 . . . . . . . . . . F . . . . . . . . .
[1]3a4o.x stu 35 . . . . . . . . . . . . . . . . . . . .
[1]2zv7.a none . . . . . . . . . . F . . . . . . . . .
[1]2zv8.a anp 31 . . . . . . . . . . F . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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