KS6A3_HUMAN_398_740

Ribosomal protein S6 kinase alpha-3 [Protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (KS6A3_HUMAN):D: Protein kinase 2 (428:431,434:436,449,451,467,477,491,493:496,499,543,544,546,560,561)428:431,434:436,449,451,467,477,491,493:496,499,543,544,546,560,561
Metals (Me):Na

Full PDB list

2qr7,2qr8,4d9t,4d9u,4jg6,4jg7,4jg8,4m8t,4mao

Contact map

[download in TSV format]
   
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ligand
A1 Me
I
4
2
8
G
4
2
9
V
4
3
0
G
4
3
1
S
4
3
4
V
4
3
5
C
4
3
6
A
4
4
9
K
4
5
1
L
4
6
7
I
4
7
7
V
4
9
1
T
4
9
3
E
4
9
4
L
4
9
5
M
4
9
6
G
4
9
9
S
5
4
3
N
5
4
4
L
5
4
6
C
5
6
0
D
5
6
1
[1]4d9t.a 0jg 29 . . . . . . . . . . . . . . . . . . . . . . Na
[1]4d9u.a 0jh 32 . . . . . . * . . . . . . . . . . . . . . . Na
[1]4jg8.a 1le 33 . . . . . . * . . . . . M . . . . . . . . .
[1]4mao.a 28d 30 . . . . . . * . . . . . M . . . . . . . . . Na
[1]4jg7.a 1lc 24 . . . - . . * . . . . . . . . . . . . . . . Na
[1]4m8t.a rmm 18 . . . . . . * . . . . . M . . . . . . . . . Na
[1]4jg6.a 1lb 16 . - - - . . * . . . . . . . . . . . . . . . Na
[1]2qr7.a none . . . . . . . . . . . . . . . * . . . . . . Na
[1]2qr8.a none . . . . . . . . . . . . . . . . . . . . . . Na

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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