KS6A1_HUMAN_33_353

Ribosomal protein S6 kinase alpha-1 [Protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (KS6A1_HUMAN):D: Protein kinase 1 (68:72,76,92,94,125,141:145,147,148,189,191,192,194,204,205)68:72,76,92,94,125,141:145,147,148,189,191,192,194,204,205

Full PDB list

2z7q,2z7r,2z7s

Contact map

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ligand
A1
L
6
8
G
6
9
Q
7
0
G
7
1
S
7
2
V
7
6
A
9
2
K
9
4
V
1
2
5
L
1
4
1
D
1
4
2
F
1
4
3
L
1
4
4
R
1
4
5
G
1
4
7
D
1
4
8
K
1
8
9
E
1
9
1
N
1
9
2
L
1
9
4
T
2
0
4
D
2
0
5
[1]2z7s.a p01 27 . . . . . . . . . . . . . . . . . . . . . .
[1]2z7q.a acp,mg 32 . . . . . . . . . . . . . . . . . . . . . .
[1]2z7r.a stu 35 . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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