KPCA_HUMAN_157_292

Protein kinase C alpha type [Protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (KPCA_HUMAN):D: C2 (187:189,193,216,247:250)187:189,193,216,247:250
 • A2 (KPCA_HUMAN):D: C2 (203,207,208,238)203,207,208,238
Metals (Me):Ca

Full PDB list

1dsy,3gpe,3rdj,3twy,4dnl,4l1l (redundant pocketome entry)

Contact map

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ligand
A1 A2 Me
D
1
8
7
P
1
8
8
N
1
8
9
D
1
9
3
R
2
1
6
W
2
4
7
D
2
4
8
R
2
4
9
T
2
5
0
D
2
0
3
E
2
0
7
S
2
0
8
R
2
3
8
[1]1dsy.a psf 25 . . . . . . . . . . . . . Ca
[2]3rdj.a none . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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