KIT_HUMAN_550_935

Mast/stem cell growth factor receptor Kit [Protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (KIT_HUMAN):D: Protein kinase (595:601,603,621:623,640,643,644,647,653,654,668,670:674,676,677,783,788:791,796,797,799,808:811)
557
557,595:601,603,621:623,640,643,644,647,653,654,668,670:674,676,677,783,788:791,796,797,799,808:811

Full PDB list

1pkg,1t45,1t46,3g0e,3g0f,4hvs,4u0i (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1
W
5
5
7
L
5
9
5
G
5
9
6
A
5
9
7
G
5
9
8
A
5
9
9
F
6
0
0
G
6
0
1
V
6
0
3
A
6
2
1
V
6
2
2
K
6
2
3
E
6
4
0
V
6
4
3
L
6
4
4
L
6
4
7
I
6
5
3
V
6
5
4
V
6
6
8
T
6
7
0
E
6
7
1
Y
6
7
2
C
6
7
3
C
6
7
4
G
6
7
6
D
6
7
7
L
7
8
3
C
7
8
8
I
7
8
9
H
7
9
0
R
7
9
1
R
7
9
6
N
7
9
7
L
7
9
9
I
8
0
8
C
8
0
9
D
8
1
0
F
8
1
1
[1]4hvs.a 647 28 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3g0e.a b49 22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]1t46.a sti 37 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]4u0i.a 0li 39 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]1pkg.b adp,mg 28 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1t45.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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