IRE1_YEAST_644_1115

Serine/threonine-protein kinase/endoribonuclease IRE1 [Protein kinase superfamily. Ser/Thr protein kinase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (IRE1_YEAST):D: Protein kinase (680:684,687,689,700,702,729,745:751,754,801,802,804,827,828)680:684,687,689,700,702,729,745:751,754,801,802,804,827,828
Metals (Me):Mg/Si

Full PDB list

2rio,3lj0,3lj1,3lj2 (redundant pocketome entry)

Contact map

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ligand
A1 Me
L
6
8
0
G
6
8
1
Y
6
8
2
G
6
8
3
S
6
8
4
T
6
8
7
V
6
8
9
A
7
0
0
K
7
0
2
I
7
2
9
L
7
4
5
E
7
4
6
L
7
4
7
C
7
4
8
N
7
4
9
L
7
5
0
N
7
5
1
D
7
5
4
Q
8
0
1
N
8
0
2
L
8
0
4
S
8
2
7
D
8
2
8
[1]3lj1.a dki 28 . . . . . . . . . . . . . . . . . . . . . . .
[1]3lj2.a iza 23 . . . . . . . . . . . . . . . . . . . . . . .
[1]2rio.b adp 27 . . . . . . . . . . . . . . . . . . . . . . . Mg,Si

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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