ILK_HUMAN_178_452_ATPsite

Integrin-linked protein kinase [Protein kinase superfamily. TKL Ser/Thr protein kinase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ILK_HUMAN):R: PH-like
mediates interaction with TGFB1I1 (200,202,204,207)
D: Protein kinase (200,202,204,207,218,220,269:272,279,323,326,339,341)
200,202,204,207,218,220,269:272,279,323,326,339,341
Metals (Me):Mn

Full PDB list

3kmu,3kmw,3rep (redundant pocketome entry)

Contact map

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ligand
A1 Me
N
2
0
0
N
2
0
2
S
2
0
4
L
2
0
7
V
2
1
8
K
2
2
0
T
2
6
9
H
2
7
0
W
2
7
1
M
2
7
2
N
2
7
9
R
3
2
3
M
3
2
6
D
3
3
9
K
3
4
1
[1]3kmu.a none . . . . . . . . . * . . * . .
[1]3rep.a atp 31 . . . . . . . . . . . . . . . Mn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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