HSD_STREX_2_255

3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase [Short-chain dehydrogenases/reductases (SDR) family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer
 • A1 (HSD_STREX):13,16,18,37,39,59:61,87:89,91:93,110,137:139,146,148,149,152,156,182:185,189,190,193,24313,16,18,37,39,59:61,87:89,91:93,110,137:139,146,148,149,152,156,182:185,189,190,193,243
 • A2 (HSD_STREX):253253

Full PDB list

1hdc,2hsd

Contact map

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ligand
A1 A2
G
1
3
R
1
6
L
1
8
D
3
7
L
3
9
L
5
9
D
6
0
V
6
1
N
8
7
A
8
8
G
8
9
S
9
1
T
9
2
G
9
3
I
1
1
0
I
1
3
7
S
1
3
8
S
1
3
9
L
1
4
6
L
1
4
8
T
1
4
9
Y
1
5
2
K
1
5
6
P
1
8
2
G
1
8
3
M
1
8
4
T
1
8
5
M
1
8
9
T
1
9
0
T
1
9
3
W
2
4
3
M
2
5
3
[1]1hdc.b cbo 41 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2hsd.c nad 44 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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