HRH1_HUMAN_20_487

Histamine H1 receptor [G-protein coupled receptor 1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (HRH1_HUMAN):R: Important for agonist binding (107,108,111,112)
R: Important for agonist binding (424,428)
115,158,194,198,431,432,435,454,458
107,108,111,112,115,158,194,198,424,428,431,432,435,454,458

Full PDB list

3rze

Contact map

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ligand
A1
D
1
0
7
Y
1
0
8
S
1
1
1
T
1
1
2
I
1
1
5
W
1
5
8
T
1
9
4
N
1
9
8
F
4
2
4
W
4
2
8
Y
4
3
1
F
4
3
2
F
4
3
5
I
4
5
4
Y
4
5
8
[1]3rze.a 5eh,d7v 42 . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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