HNMT_HUMAN_1_292

Histamine N-methyltransferase [Class I-like SAM-binding methyltransferase superfamily. HNMT family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (HNMT_HUMAN):9,15,16,19,22,28,29,59:62,66,89:91,94,119,120,142:144,146,147,173,179,183,193,195:198,243,246,2839,15,16,19,22,28,29,59:62,66,89:91,94,119,120,142:144,146,147,173,179,183,193,195:198,243,246,283

Full PDB list

1jqd,1jqe,2aot,2aou,2aov,2aow,2aox (redundant pocketome entry)

Contact map

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ligand
A1
F
9
Y
1
5
V
1
6
F
1
9
F
2
2
E
2
8
H
2
9
I
5
9
G
6
0
G
6
1
G
6
2
I
6
6
E
8
9
P
9
0
S
9
1
Q
9
4
T
1
1
9
S
1
2
0
I
1
4
2
Q
1
4
3
M
1
4
4
Y
1
4
6
Y
1
4
7
V
1
7
3
W
1
7
9
W
1
8
3
D
1
9
3
L
1
9
5
C
1
9
6
Q
1
9
7
Y
1
9
8
F
2
4
3
E
2
4
6
N
2
8
3
[1]1jqe.a qun,sah 54 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1jqe.b sah 26 - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2aou.b cqa 23 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2aot.b 2pm,sah 45 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2aov.a 4di,c2m 28 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2aow.a tha 15 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1jqd.a hsm,sah 34 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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