HEPS_HUMAN_46_417

Serine protease hepsin [Peptidase S1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (HEPS_HUMAN):D: Peptidase S1 (187,188,203,204,206,243,252,254,301,331,347:351,353,375:381,388)187,188,203,204,206,243,252,254,301,331,347:351,353,375:381,388

Full PDB list

1o5e,1o5f,1p57,1z8g,3t2n,5ce1

Contact map

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ligand
A1
L
1
8
7
C
1
8
8
H
2
0
3
C
2
0
4
P
2
0
6
Y
2
4
3
E
2
5
2
N
2
5
4
Y
3
0
1
Q
3
3
1
D
3
4
7
A
3
4
8
C
3
4
9
Q
3
5
0
G
3
5
1
S
3
5
3
V
3
7
5
S
3
7
6
W
3
7
7
G
3
7
8
T
3
7
9
G
3
8
0
C
3
8
1
G
3
8
8
[1]5ce1.a 50k 25 . . . . . . - . . . . . . . . . . . . . . . . .
[1]1o5e.h 132 26 . . . . . . - . . . . . . . . . . . . . . . . .
[1]1o5f.h cr9 28 . . . . . . - . . . . . . . . . . . . . . . . .
[1]1p57.b cr4 19 . . . . . . - . . . . . . . . . . . . . . . . .
[1]1z8g.a aceKQLar7.0qe 41 . . * . . . . . . . . . . . . * . . . . . . . .
[1]3t2n.a none . . . . . . . . - . - - - - . . . . - - - - - .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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