HCK_HUMAN_246_526

Tyrosine-protein kinase HCK [Protein kinase superfamily. Tyr protein kinase family. SRC subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (HCK_HUMAN):D: Protein kinase (268,269,271,276,288:290,302,305,306,309,318,320,331,333:336,339,340,343,385,386,388,398:402)268,269,271,276,288:290,302,305,306,309,318,320,331,333:336,339,340,343,385,386,388,398:402

Full PDB list

1ad5,1qcf,2c0i,2c0o,2c0t,2hck,2hk5,3vry,3vrz,3vs0,3vs1,3vs2,3vs3,3vs4,3vs5,3vs6,3vs7,4lud,4lue (redundant pocketome entry)

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1
L
2
6
8
G
2
6
9
G
2
7
1
V
2
7
6
A
2
8
8
V
2
8
9
K
2
9
0
F
3
0
2
E
3
0
5
A
3
0
6
M
3
0
9
V
3
1
8
L
3
2
0
I
3
3
1
T
3
3
3
E
3
3
4
F
3
3
5
M
3
3
6
G
3
3
9
S
3
4
0
D
3
4
3
A
3
8
5
N
3
8
6
L
3
8
8
A
3
9
8
D
3
9
9
F
4
0
0
G
4
0
1
L
4
0
2
[1]2hk5.a 1bm 32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vrz.b vrz 32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vs0.b vs0 30 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vs1.b vsa 31 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vs4.a vsf 29 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vs5.a vsg 30 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vs6.a vsh 29 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vry.a b43 28 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vs7.a ks1 24 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vs2.a vsb 36 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1qcf.a pp1 21 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4lud.a sk8 21 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4lud.b ca,sk8 22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2c0t.a ca,l3g 44 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2c0i.a l1g 44 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2hck.a que 22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2c0o.a l2g 46 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1ad5.a anp,ca 32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3vs3.a vse 36 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
Similar entries
Feedback