GSTM2_HUMAN_2_218

Glutathione S-transferase Mu 2 [GST superfamily. Mu family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (GSTM2_HUMAN):D: GST N-terminal (7,8,10,12,13,35,43,46,50,59:61,72,73)
R: Glutathione binding (7,8)
R: Glutathione binding (43,46)
R: Glutathione binding (59,60)
R: Glutathione binding (72,73)
D: GST C-terminal (108,112,116,166)
209,210,212
7,8,10,12,13,35,43,46,50,59:61,72,73,108,112,116,166,209,210,212
 • A2 (GSTM2_HUMAN):D: GST C-terminal (106)106

Full PDB list

1hna,1hnb,1hnc,1xw5,1ykc,2ab6,2c4j,2gtu,3gtu,3gur (redundant pocketome entry)

Contact map

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ligand
A1 A2
Y
7
W
8
I
1
0
G
1
2
L
1
3
M
3
5
R
4
3
W
4
6
K
5
0
N
5
9
L
6
0
P
6
1
Q
7
2
S
7
3
R
1
0
8
A
1
1
2
Y
1
1
6
R
1
6
6
F
2
0
9
T
2
1
0
M
2
1
2
D
1
0
6
[1]2c4j.b gso 29 . . . . . . . . . . . . . . . . . . . S . .
[1]2ab6.c gsm 21 . . . . . . . . . . . . . . . . . . . . . .
[1]3gur.c byg 40 . . . . . . . . . . . . . . . . . . . . . .
[1]1xw5.a gsh 20 . . . . . . . . . . . . . . . . . . . . . .
[1]1ykc.a gds 40 . . . . . . . . . . . . . . . . . . . . . .
[1]1hnc.c gdn 20 . . . . . . . . . . . . . . . . . . . . . .
[1]2gtu.a none . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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