GSTM1_RAT_2_218

Glutathione S-transferase Mu 1 [GST superfamily. Mu family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (GSTM1_RAT):D: GST N-terminal (7,8,10,12,13,35,43,46,50,59:61,72,73)
R: Glutathione binding (7,8)
R: Glutathione binding (43,46)
R: Glutathione binding (59,60)
R: Glutathione binding (72,73)
D: GST C-terminal (105,108,112,116,208)
209,210
7,8,10,12,13,35,43,46,50,59:61,72,73,105,108,112,116,208:210
 • A2 (GSTM1_RAT):D: GST C-terminal (106)106

Full PDB list

1mtc,2gst,3fyg,3gst,4gst,5fwg,5gst,6gst,6gsu,6gsv,6gsw,6gsx,6gsy (redundant pocketome entry); 1gsb,1gsc (unprocessed)

Contact map

[download in TSV format]
   
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ligand
A1 A2
Y
7
W
8
V
1
0
G
1
2
L
1
3
M
3
5
R
4
3
W
4
6
K
5
0
N
5
9
L
6
0
P
6
1
Q
7
2
S
7
3
M
1
0
5
R
1
0
8
I
1
1
2
Y
1
1
6
I
2
0
8
F
2
0
9
S
2
1
0
D
1
0
6
[1]1mtc.b gpr 35 . . . . . . . . . . . . . . . . . F . . . .
[1]4gst.a gtd 35 . . . . . . . . . . . . . . . . . . . . . .
[1]5gst.b gdn 32 . . . . . . . . . . . . . . . . . . . . . .
[1]2gst.a gps 35 . . . . . . . . . . . . . . . . . . . . . .
[1]3fyg.b gpr 35 * . . . . . . . . . . . . . . . . . . . . .
[1]6gst.a gsh 20 . . . . . . . . . . . . . . . . . . . . . .
[1]3gst.a gpr 35 . . . . . . . . . . . . . . . . . . . . . .
[1]6gsy.a gsh 20 F . . . . . . . . . . . . . . . . . . . . .
[1]5fwg.b gpr 35 . * . . . . . * . . . . . . . . . . . . . .
[1]6gsx.a gps 35 F . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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